Protein Alignment Mcm7 and Mcmdc2

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_006237843.1
• Gene: Mcmdc2 / 500392
• RGDID: 1561068
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 138/688 - (20%)
• Similarity: 229/688 - (33%)
• Gaps: 190/688 - (27%)

  Fly    83 ELLPSYKQQEVHAKDALDVYIE-----HRLMMESRTRNPMEQRDERNSFPSELMKRFEVGFKP-- 140
            |:....|..::..|:|..||::     .:.|.:.:..|..:|        |..:.||.:...|
  Rat     2 EITNMEKMGKLPMKEAALVYLDRSGGLQKFMDDCKYYNDSKQ--------SYAVYRFSILINPCD 58

  Fly   141 ---LSTEKAHSI--REVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGS-ETYQPVN-SL 198
               |..|..:.|  ..:||..:.:.|        |       .||..|....|. :|...:| .|
  Rat    59 VVELDAELGNHILHHPLKAAQVFQSV--------C-------FVAVKTLSLIGKLQTETQINIVL 108

  Fly   199 SFTPVHDCPS---DDCR--VNKAGGRLYLQ-------------TRGSKFVKFQEVKMQEHSDQVP 245
            ..|.:...||   |.|.  :|.|..|.|:.             |:|::|:...||.......|..
  Rat   109 KLTHLPSLPSYSLDLCEFPLNYASQRFYMMQGIVIAMTTVTKYTQGARFLCSDEVCPFSKGFQYI 173

  Fly   246 VGHIP---RSMTI----MCR------GEVTRMAQPGDHIVVS----------------------- 274
            ..|:|   .|.|:    :||      .|..:....||..::.
  Rat   174 RVHVPGATESATVRNDFLCRLCSSSLQEDRKFRVLGDKQIIEIITTKVLHAFQGDPKNQPFRFQS 238

  Fly   275 -GVFL-----PLMRTGFAQMIQGL-----LSETFLQAHRIICINKNDEISDKDAELTP--EELEE 326
             .|||     ..|:.|....|.|:     .|:|.|      |:..|        .:||  .::..
  Rat   239 LSVFLRDELVNKMKIGNEYKIIGIPVCVKTSQTAL------CVEAN--------SITPYTAKVPS 289

  Fly   327 LAQDDFYERLA---------TSLAPEIY-------GHLDVKKALLLLLVGGVDKRPDGMKIRGNI 375
            ...|:|...|:         |::...::       |..::.|  |.||:..|..|....:....:
  Rat   290 GISDNFRCLLSLTSSSCWRFTAILANVFASHIVPLGTYNLLK--LCLLMSLVQTRDCSSERENCL 352

  Fly   376 NICLMGDPGVAKSQLLGYISRLAVRSQY---------TTGRGSSGVGLTAAVMKDPLTGEMTLEG 431
            :|.::....:...:||.:...|..|...         |..|...|            ||.::::.
  Rat   353 DILVITSDTLLVDRLLNFSMNLVSRGIRHPVCTEVFPTVSRDKYG------------TGAVSIQA 405

  Fly   432 GALVLADQGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAG--------------IMTTLNARV 482
            |:.:||..|||.|.:...........:...:|.:::::...|              |..:..:.|
  Rat   406 GSALLARGGVCFIGDLTSHKKDKLEQLQSALESRSVTVFIPGKKFGDDFDQQMTFPIQCSFWSFV 470

  Fly   483 SILAAANPAFGRYNPRRTVEQNIQL---------PAALLSRFDLLWLIQDKPDRDNDLRLAKHIT 538
            .:.:::         ||.|::...|         ||.|...|.||...::.......|...:|..
  Rat   471 DMDSSS---------RRNVQKASTLIGQMDCSLIPANLAEAFGLLVNCKESSPCHPLLPTVQHTL 526

  Fly   539 YVHSHSKQPP-TRVKALDMNLMRRYINLCKRKNPTIPDELTDYIVGAYVELRREARNQKDMTFTS 602
            ......|.|| ...|........:.:...|..|.....|....|.|.|:..||...:....:..|
  Rat   527 KKAVDPKGPPYLASKQFTTEDFEKLLAFAKNLNVEFSLEAERMIHGYYLASRRIRTDSIHGSKLS 591

  Fly   603 ARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMS 640
            |..|..::.||.|.|||.|.:.|.::||..|..|.|:|
  Rat   592 ANALKYLVSLSEAHARLNLRNKVLREDVLIAALLFEIS 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	2/13 (15%)
		MCM	145..641	CDD:214631	123/616 (20%)
Mcmdc2	XP_006237843.1	MCM	<389..630	CDD:278895	57/262 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900