Protein Alignment Mcm7 and mcm4

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_944595.2
• Gene: mcm4 / 337598
• ZFINID: ZDB-GENE-030131-9544
• Length: 845
• Species: Danio rerio
• Alignment Length: 653
• Identity: 228/653 - (34%)
• Similarity: 347/653 - (53%)
• Gaps: 60/653 - (9%)

  Fly    10 RESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAVVDNCRRYT 74
            :|..:.||.:|  .|.|.::|...|..|      .:.|....||:::...|.:...   ||....
Zfish   145 KEKFQRFLQQF--TDPDSREEENAGLDL------NEPLYMQKLDEISVVGEPVLNV---NCTHIQ 198

  Fly    75 SIFSDVIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFPSELMKRFEVGFK 139
            :..:|:..:|: .|.|:.:   ...|:.:.....               :.||..:::. ::..:
Zfish   199 TFDADLYRQLI-CYPQEVI---PTFDMSVNELFF---------------DRFPDSVLEH-QIQVR 243

  Fly   140 PLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSETYQPVNSLSFTPVH 204
            |.|..|..::|.:..:.|.:|:|:.|:|.|.:::.|.|..|.:.|..|...|...|:........
Zfish   244 PYSAIKTRNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFRCQVCAFNTRVEVDRGRIAEPA 308

  Fly   205 DCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVTRMAQPGD 269
            .|  .:|....:   :.|....|.|...|.:|:||..:.:|.|..|.:..:....::....||||
Zfish   309 VC--RNCNTTHS---MALVHNRSVFSDKQMIKLQESPEDMPAGQTPHTTVVYAHNDLVDKVQPGD 368

  Fly   270 HIVVSGVFLPL-MRTGFAQMIQGLLSETFLQAHRIICINKNDEIS----DKDAE---LTPEE--- 323
            .:.::|::... ||....|.....:.:|.:.|   |...|.||..    |:|.|   .|.|.
Zfish   369 RVNITGIYRAAPMRLNPRQSQVKSVYKTHIDA---IHFRKTDEKRLHGLDEDGEQKLFTKERVAL 430

  Fly   324 LEEL-AQDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDK---RPDGMKIRGNINICLMGDPG 384
            |:|| |:.|.||||:::|||.||.|.|:||.:||.|.||..|   :......|..:||.|.||||
Zfish   431 LKELAAKPDVYERLSSALAPSIYEHEDIKKGILLQLFGGTRKDFTQTGRGNFRAEVNILLCGDPG 495

  Fly   385 VAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCIDEFDK 449
            .:|||||.|:..|..|.|||:|:|||.|||||.|||||.|.::.|:.|||||:|.|:||||||||
Zfish   496 TSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDK 560

  Fly   450 MADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAALLSR 514
            |:|..|:.:||||||||:|||||||:..||||.||||||||...::||::|..:|||||..||||
Zfish   561 MSDNTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPVESQWNPKKTTIENIQLPHTLLSR 625

  Fly   515 FDLLWLIQDKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMNLMRRYINLCKRK-NPTIPDELT 578
            |||::|:.|..|...|.|||.|:..::..|:: ....:.|||.:::.||...:.. :|.:.:|.:
Zfish   626 FDLIFLMLDPQDEAYDRRLAHHLVSLYYQSEE-QIEEEHLDMAVLKDYIAFARTTVHPRLSEEAS 689

  Fly   579 DYIVGAYVELRREARNQKDMTFTSARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMSKDS 643
            ..::.|||::|: ..:.:.|.....|.|..::||:.|.|::|.|..||..||.||.||   .:::
Zfish   690 QALIEAYVDMRK-IGSGRGMVSAYPRQLESLIRLAEAHAKVRFSGKVETIDVEEAKRL---HREA 750

  Fly   644 LNQ 646
            |.|
Zfish   751 LKQ 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	18/83 (22%)
		MCM	145..641	CDD:214631	202/511 (40%)
mcm4	NP_944595.2	MCM_N	147..269	CDD:291233	28/152 (18%)
		MCM	249..752	CDD:214631	202/515 (39%)
		P-loop_NTPase	487..626	CDD:304359	90/138 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820