Protein Alignment Mcm7 and AgaP_AGAP002581

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_312355.3
• Gene: AgaP_AGAP002581 / 3290641
• VectorBaseID: AGAP002581
• Length: 685
• Species: Anopheles gambiae
• Alignment Length: 743
• Identity: 155/743 - (20%)
• Similarity: 262/743 - (35%)
• Gaps: 225/743 - (30%)

  Fly    37 LVKLAHR---EQVLITIDLDDLAEFNESLAEAVVDNCRR--YTSIFSDVIAELLPSYKQQEVHAK 96
            |||..|.   |..|:..:.....||..:||.  .|.|.:  :.::.:|:  |..|.|    ..|.
Mosquito    80 LVKHYHDYRCEYSLLEAESSGSFEFKLNLAR--TDICLKDAWPTLQADI--EAFPEY----TIAC 136

  Fly    97 DALDVYIEHRLMMESRTRNPMEQRDERNSFPSELMKRFEVGFKPLSTEKAH------SIREVKAQ 155
            ..|.:|         ||.....|.|   .|..|.:   |:   |..|.:.|      .|..:.|.
Mosquito   137 MGLGMY---------RTVAATHQAD---PFSPETL---EI---PKITARLHLFGPEQPISTIDAS 183

  Fly   156 HIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSETYQPVNSLSFTPVHD--------------- 205
            :..||||:.|.:...:|......:..|.|..|                ||
Mosquito   184 YTDKLVTIGGTIVHDSEPIVTSTLRAYKCRYC----------------HDTIVLERHHNRHTTRQ 232

  Fly   206 --CPSDDCRVNKAGGRLYL------QTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVT 262
              |  :.|  |..||..|.      :....:.:..|:.::.:...|.....:|.::        .
Mosquito   233 WIC--EQC--NAGGGIEYCSASVLNRDEAHQLIMVQDARVSKTRCQTIEVKVPCAL--------V 285

  Fly   263 RMAQPGDHIVVSGVFLPLMRTGFAQMIQGLLSETFLQAHRIICINKNDEISDKDAELTPEELEEL 327
            ...|.||::.::||.             .:.|..|:.|   |||.|:.:....:..:...::|.:
Mosquito   286 DGLQAGDNVTITGVL-------------KIDSSKFVAA---ICIRKDLDNGTIERNVNSTDVEVI 334

  Fly   328 ----AQDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKRPDGMKIRGNINICLMGDPGVAKS 388
                ::...::.|..||.|.:.|...||...||.|          ....|:::: |:.|....||
Mosquito   335 NAIRSEACLFKLLVQSLCPAVAGLETVKAGSLLAL----------FNTTGDVHV-LLADIDSGKS 388

  Fly   389 QLL----------GYIS----RLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQ 439
            |.|          |::.    |..||.||             .:.|.|            .|..|
Mosquito   389 QKLLDSCMAASPKGFVENDPYRDEVRVQY-------------LMAKSP------------ALPGQ 428

  Fly   440 GVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQN 504
            |||||:..|||   |:.   |::|:         ::|....:.::|....|..|..:.|:....|
Mosquito   429 GVCCIERIDKM---DKL---EMLEK---------MLTDTPPQTTLLVTVMPNRGVLDTRKPFLDN 478

  Fly   505 IQLPAALLSRFDLLWLIQD---KPDR---DNDLRL---AKHITYVHSHSKQPPTRVKALDMNLMR 560
            ..||..|:.:|.|::|::|   .|:.   .:.:||   .....|..||.....|..   .|.|:.
Mosquito   479 FILPRNLMEKFALVFLMEDVIIPPEELVCSDGVRLHPETPSANYARSHCNPEFTEE---SMALLE 540

  Fly   561 RYINLCKRKNPTIPDELTDYIVGAYVELRREARNQKDMTFTSARNLLGILRLSTALARLRLSDSV 625
            |:.:           ||  |.:..::.:            |:...:..|..::.|.||:.||.::
Mosquito   541 RFFS-----------EL--YSMPHWLNI------------TNGVKMAQIKSMALARARIDLSPAI 580

  Fly   626 EKDDVAEALRLLEMS-------KDSLNQIH-EHQKGHVPNTSDRIFAIV---RELAGSGKAVKIS 679
            ..:.|.:.:|::..|       .|....:. ..:||.|...|.|.|..|   |.:....|:..:.
Mosquito   581 TTEHVMDTVRIVSRSWYDRYDTDDRAPTVQLPAKKGGVKAASIRQFLEVLRARSVEHKTKSFSLK 645

  Fly   680 DIMDRCTTKGFKPDQVDKCIDDYEELNV 707
            ::......:|. |...|:.|   |:||:
Mosquito   646 ELRALIEEEGM-PGFEDEII---EKLNI 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	17/64 (27%)
		MCM	145..641	CDD:214631	110/558 (20%)
AgaP_AGAP002581	XP_312355.3	MCM	176..595	CDD:214631	108/541 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	1	1.000	-	-		FOG0003915
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820