Protein Alignment Mcm7 and Mcm3

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_001178734.2
• Gene: Mcm3 / 316273
• RGDID: 1305168
• Length: 813
• Species: Rattus norvegicus
• Alignment Length: 772
• Identity: 241/772 - (31%)
• Similarity: 365/772 - (47%)
• Gaps: 176/772 - (22%)

  Fly     2 ARRDYAQDRESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAV 66
            |:|||..       ||       ||.:.:.:|.:::.:|....|..:.::::||...||..|..:
  Rat    15 AQRDYLD-------FL-------DDEEDQGIYQNKVRELISDNQYRLIVNVNDLRRKNEKRANRL 65

  Fly    67 VDNCRR----YTSIFSDVIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFP 127
            ::|...    :.....|.:|.:..:|.:|
  Rat    66 LNNAFEELVAFQRALKDFVASIDATYAKQ------------------------------------ 94

  Fly   128 SELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTC---DRCGS 189
               .:.|.:|.:.....|..|.|.:.:..:..:|.|.||||:|:.|:|.:|.:.:.|   .:...
  Rat    95 ---YEEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIE 156

  Fly   190 ETYQPVNSL-SFTPVHDCPSDDCRVNKAGGRLYLQTRG--SKFVKFQEVKMQEHSDQVPVGHIPR 251
            ..|..:.:| :|......|:.|...|.      |:|..  |.:...|.:.:||..::.|.|.:||
  Rat   157 RRYSDLTTLVAFPSSSVYPTKDEENNP------LETEYGLSVYKDHQTITIQEMPEKAPAGQLPR 215

  Fly   252 SMTIMCRGEVTRMAQPGDHIVVSGVF--LPLMRTGFAQMIQGLLSETFLQAHRIICINKNDEISD 314
            |:.::...::....:|||.|.|.|.:  ||..:.|:.       |.||    |.:.|..|.:...
  Rat   216 SVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGGYT-------SGTF----RTVLIACNVKQMS 269

  Fly   315 KDAE--LTPEELEELAQ------DDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKR-PDGMK 370
            ||.:  .:.:::.::.:      .|.:|:||.||||.|:||..||||:|.||:|||::. .:|..
  Rat   270 KDIQPAFSADDIAKIKKFSKTRSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSH 334

  Fly   371 IRGNINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALV 435
            |||:|||.|:|||.|||||||.|:...|.|:..|||||||||||||||..|..|||..||.||:|
  Rat   335 IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMV 399

  Fly   436 LADQGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRT 500
            |||:||.||||||||:|.|||||||||||..::||||||...||||.|:||||||.:|||:..:|
  Rat   400 LADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKT 464

  Fly   501 VEQNIQLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSH---------------------- 543
            ..:||.|..:||||||||:::.|:.|.:.|..::.|:..:|.:
  Rat   465 PMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYRAPGEQDGDALPLGSSVDILAT 529

  Fly   544 -------SKQPPTRV----------------KALDMNLMRRYINLCKRKNPTIPDELTDYIVGAY 585
                   ..|..||:                |.:....|::||::.|...||:..|...||...|
  Rat   530 DDPDFTQDDQQDTRIYEKHDNLLHGSKKKREKMVSAAFMKKYIHVAKIIKPTLTQESAAYIAEEY 594

  Fly   586 VELRREARNQKDMTFTS---ARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMSKDSLNQI 647
            ..||.:.....|...||   ||.|..::||:||.|:.|:|.:|:..|..||:.|::.:  ...::
  Rat   595 SRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA--YFKKV 657

  Fly   648 HEHQKGHVPNTSDRIFAIVRELAGSGKAVKISDIMDRCTTKGFKPDQVDKCIDDYEE 704
            .|.:|                                   |..||.:.:..::|.||
  Rat   658 LEKEK-----------------------------------KRKKPSEDESDLEDEEE 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	17/87 (20%)
		MCM	145..641	CDD:214631	210/560 (38%)
Mcm3	NP_001178734.2	MCM_N	17..129	CDD:291233	27/164 (16%)
		MCM	109..654	CDD:214631	210/563 (37%)
		P-loop_NTPase	340..479	CDD:304359	92/138 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820