Protein Alignment Mcm7 and mcm3

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_587795.1
• Gene: mcm3 / 2538838
• PomBaseID: SPCC1682.02c
• Length: 879
• Species: Schizosaccharomyces pombe
• Alignment Length: 704
• Identity: 231/704 - (32%)
• Similarity: 359/704 - (50%)
• Gaps: 124/704 - (17%)

  Fly    10 RESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAVVDNCRRYT 74
            ::.::.| .|:.:.|.|.....:|...::::.:..|..:.:::|:|.::|..||:.|:.....|.
pombe    11 KDRVRIF-QEYLEHDTDDANVTLYQEAILRMLNMGQRRLIVNIDELRDYNRELADGVLLKPLEYV 74

  Fly    75 SIFSDVIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFPSELMKRFEVGFK 139
            ..|.:.:..::.:.....|| ||..|                               |.|.|||:
pombe    75 EPFDEALRNVVSTLIDPVVH-KDLKD-------------------------------KLFYVGFR 107

  Fly   140 PLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSETYQPV------NSL 198
            ....:...:.|.::|.|:.|::::.||||||:.|:|.::.:.:.|:......::..      ..|
pombe   108 GSFGDHHVNPRTLRAMHLNKMISLEGIVTRCSFVRPKVIKSVHYCEATKRHHFKQYADATMNGGL 172

  Fly   199 SF-TPVHDCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVT 262
            || :.|:  |:.|    :.|..|.::...|.|...|.:.:||..::.|.|.:|||:.|:...::.
pombe   173 SFQSTVY--PTQD----ENGNPLSIEFGFSTFRDHQSISLQEMPERAPPGQLPRSIDILLDDDLV 231

  Fly   263 RMAQPGDHIVVSGVFLPLMRTGFAQMIQGLLSETF---LQAHRIICINKND----------EISD 314
            ...:|||.:.:.|.:     ........|..|.||   |.|:.::.:....          :|:|
pombe   232 DTVKPGDRVNIVGQY-----RSMGSKTSGNTSATFRTVLLANNVVLLGNKPGLGNVGGGALDITD 291

  Fly   315 KDAELTPEELEELA-QDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKR-PDGMKIRGNINI 377
            .|.    ..:.:|| :.:.:|.|:|||||.|||:..||:|:||||:||.:|. .:|..|||:|||
pombe   292 ADI----RNINKLARKKNVFELLSTSLAPSIYGYEYVKQAILLLLLGGTEKNLTNGTHIRGDINI 352

  Fly   378 CLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVC 442
            .::|||..||||||.::...|..:..|||||||||||||||..|..|||..||.||:||||:||.
pombe   353 LMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLADRGVV 417

  Fly   443 CIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQL 507
            ||||||||:|.||.||||||||||::||||||.|:||||.|::|||||.:|:|:.|:...|||.|
pombe   418 CIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPIYGQYDIRKDPHQNIAL 482

  Fly   508 PAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSH---SKQPPTRVK----------------- 552
            |.::|||||||:::.|..|...|..|::|:..:|.:   ..:|.|.|:
pombe   483 PDSMLSRFDLLFIVTDDIDDKKDRALSEHVLRMHRYLPPGVEPGTPVRDSLNSVLNVGATNAAGV 547

  Fly   553 -------------------------------ALDMNLMRRYINLCK-RKNPTIPDELTDYIVGAY 585
                                           .|::|.:|:||...| |.:|.:.....:||...|
pombe   548 STENVEQEVETPVWETFSSLLHANARTKKKELLNINFVRKYIQYAKSRIHPILNQATAEYITNIY 612

  Fly   586 VELRRE--ARNQKDMTFTSARNLLGILRLSTALARLRLSDSVEKDDVAEALRLL 637
            ..||.:  ..||:..:..:||.|..::|||||.|:.|||..||..|...|.::|
pombe   613 CGLRNDDLQGNQRRTSPLTARTLETLIRLSTAHAKARLSSVVEVKDAKAAEKIL 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	16/83 (19%)
		MCM	145..641	CDD:214631	207/569 (36%)
mcm3	NP_587795.1	MCM_N	17..133	CDD:291233	28/148 (19%)
		Mcm2	21..719	CDD:224162	229/693 (33%)
		P-loop_NTPase	<407..>465	CDD:304359	44/57 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810