Protein Alignment Mcm7 and mcm3

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_997732.2
• Gene: mcm3 / 192323
• ZFINID: ZDB-GENE-020419-4
• Length: 807
• Species: Danio rerio
• Alignment Length: 742
• Identity: 233/742 - (31%)
• Similarity: 361/742 - (48%)
• Gaps: 154/742 - (20%)

  Fly     2 ARRDYAQDRESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAV 66
            |:|||..       ||       ||.:.:.:|.|::.::....:..:.::|:||...||..|..:
Zfish    14 AQRDYLD-------FL-------DDDQDQGIYQSKVRQMISENKSRLIVNLNDLRRRNEKRAAKL 64

  Fly    67 VDNC----RRYTSIFSDVIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFP 127
            ::|.    ..:.....|::|.:..:|.:|
Zfish    65 LNNAFEELLAFQRALKDLVASIDATYAKQ------------------------------------ 93

  Fly   128 SELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTC---DRCGS 189
               .:.|.:|.:.....|..|.|.:.::.:|.:|.:.||||:|:.|:|.:|.:.:.|   .:...
Zfish    94 ---CEEFFIGLEGSFGSKHVSPRTLTSRLLGSMVCLEGIVTKCSLVRPKVVRSVHYCPATKKTME 155

  Fly   190 ETYQPVNSLSFTPVHDC-PSDDCRVNKAGGRLYLQTRG--SKFVKFQEVKMQEHSDQVPVGHIPR 251
            ..|..:.||...|.... |:.|...|.      |:|..  |.:...|.:.:||..::.|.|.:||
Zfish   156 RKYTDLTSLDAFPSSAIYPTKDEENNP------LETEFGLSVYKDHQTITIQEMPEKAPAGQLPR 214

  Fly   252 SMTIMCRGEVTRMAQPGDHIVVSGVF--LPLMRTGFAQMIQGLLSETFLQAHRIICINK--NDEI 312
            |:.|:...::....:|||...|.|.:  ||..:.||.       |.|| :...|.|..|  :.||
Zfish   215 SVDIILDNDLVDAVKPGDRTQVIGTYRCLPGKKGGFT-------SGTF-RTIMIACHVKQMSKEI 271

  Fly   313 SDKDAELTPEELEELAQD---DFYERLATSLAPEIYGHLDVKKALLLLLVGGVDK-RPDGMKIRG 373
            |...:.....:::...:.   :.:::||.||||.|:||..:|||:|.:|:|||:| ..:|.:|||
Zfish   272 SHYFSADDVAKIKSFCRSRSKNVFDQLARSLAPSIHGHEYIKKAILCMLLGGVEKVLENGSRIRG 336

  Fly   374 NINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLAD 438
            :||:.|:|||.|||||||.|:...|.|:..|||||||||||||||..|..|||..||.||:||.|
Zfish   337 DINVLLIGDPSVAKSQLLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLGD 401

  Fly   439 QGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQ 503
            :||.||||||||:|.|||||||||||..::||||||...||||.|:||||||.:|||:..:|..:
Zfish   402 RGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPME 466

  Fly   504 NIQLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSH------------------------- 543
            ||.|..:||||||||:::.|:.|.:.|..::.|:..:|.:
Zfish   467 NIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRDPHEQDGTALALGGTIDALATEDP 531

  Fly   544 ----------------------SKQPPTRVKALDMNLMRRYINLCKRKNPTIPDELTDYIVGAYV 586
                                  ||:...||  :....||:||::.|..:|.:..:..::|...|.
Zfish   532 DATQEEEEELQVYEKHNPLLHGSKKNKDRV--VSKAFMRKYIHVAKAISPVLTQDAANHIAEEYS 594

  Fly   587 ELRREARNQKDMTFTS---ARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMS-------- 640
            .||.:.:...|:..||   ||.|..::|||||.|:.|:|.:||..|...|:.|::.:
Zfish   595 RLRNQEQLGSDIARTSPVTARTLETLIRLSTAHAKARMSKAVELVDTEVAVELVQFAYFKKVLEK 659

  Fly   641 ---------KDSLNQIHEHQKGHVPNT 658
                     :|:.::..|.::....:|
Zfish   660 ERKRSRNGQQDAASEDEEEEEDEAQDT 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	17/87 (20%)
		MCM	145..641	CDD:214631	207/576 (36%)
mcm3	NP_997732.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820