Protein Alignment Mcm7 and AgaP_AGAP005800

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_315815.2
• Gene: AgaP_AGAP005800 / 1276468
• VectorBaseID: AGAP005800
• Length: 717
• Species: Anopheles gambiae
• Alignment Length: 718
• Identity: 553/718 - (77%)
• Similarity: 632/718 - (88%)
• Gaps: 2/718 - (0%)

  Fly     3 RRDYAQDRESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAVV 67
            :||||:|:|:||:||:||.:.:|||||.|||..||.|:|||||:.:.:||||:|.:.:.||||:.
Mosquito     2 QRDYAKDKETIKSFLAEFYREEDDGKKNFVYARQLTKIAHREQIQLVVDLDDVASYKDELAEAMQ 66

  Fly    68 DNCRRYTSIFSDVIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFPSELMK 132
            .|.|||..:|||.:.|||||||::||..||.||::|||||:|:.|...|.:.||.||:.|.||:|
Mosquito    67 VNSRRYVKLFSDAVFELLPSYKEREVTNKDTLDIFIEHRLLMQGRLHGPNDTRDARNAIPMELIK 131

  Fly   133 RFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSETYQPVNS 197
            |::|.||..|..||.|||:|||..|||||.|||||||||||||||.|||||||||||||||||.|
Mosquito   132 RYDVYFKAPSMAKAVSIRDVKADSIGKLVAVRGIVTRCTEVKPMMTVATYTCDRCGSETYQPVTS 196

  Fly   198 LSFTPVHDCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVT 262
            :||.|..:|||:|||||||||||||||||||||||||:|:|||||||||||||||:|:|||||.|
Mosquito   197 MSFKPAIECPSEDCRVNKAGGRLYLQTRGSKFVKFQEIKIQEHSDQVPVGHIPRSLTVMCRGETT 261

  Fly   263 RMAQPGDHIVVSGVFLPLMRTGFAQMIQGLLSETFLQAHRIICINKNDEISDKDAELTPEELEEL 327
            |.||||||::::|:|||:.:|||..::.|||||||:.||||:|:||:|: .:.:.|||.|||:||
Mosquito   262 RCAQPGDHVIITGIFLPIQKTGFRAVVSGLLSETFVDAHRIVCLNKSDD-GELNNELTQEELDEL 325

  Fly   328 AQDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKRPDGMKIRGNINICLMGDPGVAKSQLLG 392
            |:||||.|:|:|||||||||||||||||||||||||:.|||||||||||||||||||||||||||
Mosquito   326 AKDDFYTRIASSLAPEIYGHLDVKKALLLLLVGGVDRSPDGMKIRGNINICLMGDPGVAKSQLLG 390

  Fly   393 YISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCIDEFDKMADQDRTA 457
            ||.||||||||||||||||||||||||||||||||.||||||||||||||||||||||||:||.:
Mosquito   391 YIDRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMVLEGGALVLADQGVCCIDEFDKMADEDRVS 455

  Fly   458 IHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAALLSRFDLLWLIQ 522
            |||||||||||||||||||.||||||||||||||:||||||||:|||||||||||||||||||||
Mosquito   456 IHEVMEQQTISIAKAGIMTCLNARVSILAAANPAYGRYNPRRTIEQNIQLPAALLSRFDLLWLIQ 520

  Fly   523 DKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMNLMRRYINLCKRKNPTIPDELTDYIVGAYVE 587
            ||.||||||||||||||||||.||||:|:|.|||.|:||||.|||||.|.|..|||||||.||||
Mosquito   521 DKADRDNDLRLAKHITYVHSHGKQPPSRIKTLDMTLIRRYIALCKRKIPVITPELTDYIVNAYVE 585

  Fly   588 LRREARNQKDMTFTSARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMSKDSLNQIHEHQK 652
            |||||||.:|||||||||||||||||||||||||:|:||||||.||||||.||||||||. ||:.
Mosquito   586 LRREARNSRDMTFTSARNLLGILRLSTALARLRLADTVEKDDVKEALRLLAMSKDSLNQT-EHRD 649

  Fly   653 GHVPNTSDRIFAIVRELAGSGKAVKISDIMDRCTTKGFKPDQVDKCIDDYEELNVWQVNMGRTKI 717
            .||.||||:|||:||||||..|.||::|||:||||||:|||:||:||:.||||||||||..||||
Mosquito   650 THVQNTSDKIFALVRELAGESKTVKVADIMERCTTKGYKPDEVDECIETYEELNVWQVNQTRTKI 714

  Fly   718 TFM 720
            ||:
Mosquito   715 TFL 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	47/83 (57%)
		MCM	145..641	CDD:214631	416/495 (84%)
AgaP_AGAP005800	XP_315815.2	MCM_N	18..164	CDD:291233	82/145 (57%)
		MCM	144..639	CDD:214631	416/495 (84%)
		P-loop_NTPase	374..513	CDD:304359	130/138 (94%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	410	1.000	Domainoid score	I2035
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4323
Inparanoid	1	1.050	1128	1.000	Inparanoid score	I699
OMA	1	1.010	-	-		QHG54225
OrthoDB	1	1.010	-	-		D15169at50557
OrthoFinder	1	1.000	-	-		FOG0003915
OrthoInspector	1	1.000	-	-		oto106292
Panther	1	1.100	-	-	LDO	PTHR11630
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3219
TreeFam	1	0.960	-	-
	13	12.940