Protein Alignment Mcm7 and zmcm3

DIOPT Version :10

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_031759909.1
• Gene: zmcm3 / 100158601
• XenbaseID: XB-GENE-971646
• Length: 818
• Species: Xenopus tropicalis
• Alignment Length: 766
• Identity: 251/766 - (32%)
• Similarity: 369/766 - (48%)
• Gaps: 160/766 - (20%)

  Fly    10 RESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAVVDNCRRYT 74
            ||:.:.:| :|  .|||..:...:|.....:...|..|| |:|:|:...||..|.  :.|.|.:.
 Frog    13 REAQREYL-DF--LDDDQDQGLYHGKVRDMIGSNEHRLI-INLNDVRRKNEKRAN--LTNRRYWR 71

  Fly    75 SIF-----------------SDVIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDE 122
            .||                 .|::|.:..:|.:|
 Frog    72 LIFRLLNNAFGETIAFQRALKDLVASIDATYAKQ------------------------------- 105

  Fly   123 RNSFPSELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTC--- 184
                    .:.|.|||:.....|..|.|.:.|..:|.||.|.||||:|:.|:|.::.:.:.|
 Frog   106 --------FEEFSVGFEGSFGSKHVSPRTLTASLLGSLVCVEGIVTKCSLVRPKVLRSVHYCPAT 162

  Fly   185 DRCGSETYQPVNSLSFTPVHDC-PSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGH 248
            .:.....|..:.||...|.... |:.|...|.......|.|    :...|.:.:||..::.|.|.
 Frog   163 KKTLERKYTDLTSLEAFPSSSIYPTKDEENNPLETEYGLST----YRDHQTLSIQEMPEKAPAGQ 223

  Fly   249 IPRSMTIMCRGEVTRMAQPGDHIVVSGVF--LPLMRTGFAQMIQGLLSETFLQAHRIICINKNDE 311
            :|||:.|:...::....:|||.:.:.|::  ||..:.||.       |.||    |.|.:..|.:
 Frog   224 LPRSVDIIADDDLVDKCKPGDRVQIVGIYRCLPSKQGGFT-------SGTF----RTILLANNIK 277

  Fly   312 ISDKDAELTPE-ELEELAQ---------DDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKRP 366
            :..|  |:.|. ..:::|:         .|.:|.|:.||||.|:||..:|||:|.:|:||.:|..
 Frog   278 LMSK--EIAPTFSADDVAKIKKFCKAHSKDIFEHLSKSLAPSIHGHEYIKKAILCMLLGGNEKVL 340

  Fly   367 D-GMKIRGNINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLE 430
            | |.:|||:||:.|:|||.|||||||.|:...|.|:..|||||||||||||||..|..|||..||
 Frog   341 DNGTRIRGDINVLLIGDPSVAKSQLLRYVLYTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLE 405

  Fly   431 GGALVLADQGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRY 495
            .||:||||:||.||||||||:|.|||||||||||..::||||||...||||.|:||||||.:|||
 Frog   406 AGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIQARLNARCSVLAAANPVYGRY 470

  Fly   496 NPRRTVEQNIQLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSH----------------- 543
            :..||..:||.|..:||||||||:::.||.|.:||..:|.|:..:|.:
 Frog   471 DQYRTPMENIGLQDSLLSRFDLLFIVLDKMDAENDREIADHVLRMHRYRTPGEQDGYALPLGCSV 535

  Fly   544 ----SKQP------------------------PTRVKALDMNLMRRYINLCKRKNPTIPDELTDY 580
                :..|                        ..:.|.:.|..:|:||::.|...|.:..|..||
 Frog   536 EIFATDDPNASDVTDQELQIYEKHDNLLHGPRKNKSKIVSMQFIRKYIHVAKLIKPVLTPEAADY 600

  Fly   581 IVGAYVELRREARNQKDMTFT---SARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLE---- 638
            |...|.::|...:...|...|   :||.|..::||:||.|::|:|.::|:.|...||.|::
 Frog   601 ISQEYAKIRNHDQINNDSARTMPVTARALETMIRLATAHAKVRMSKTIERQDAETALELVQFAYF 665

  Fly   639 ---MSKDSL---NQIHEHQKGHVPNTSDRIFAIVRELAGSGKAVKISDIMD 683
               ::||..   ..:|:........:.:.|      ...|.:|.||:|..|
 Frog   666 KKVLAKDKKKTDKDLHDEILSQDSASQESI------RKSSRRAGKIADSQD 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	10..103	CDD:464206	25/109 (23%)
		MCM	145..641	CDD:475121	212/567 (37%)
zmcm3	XP_031759909.1	MCM_N	<32..115	CDD:464206	22/124 (18%)
		MCM	120..665	CDD:214631	212/561 (38%)