Protein Alignment dally and Gpc2

DIOPT Version :9

• Sequence 1: NP_001246685.1
• Gene: dally / 39013
• FlyBaseID: FBgn0263930
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_766000.1
• Gene: Gpc2 / 71951
• MGIID: 1919201
• Length: 579
• Species: Mus musculus
• Alignment Length: 616
• Identity: 134/616 - (21%)
• Similarity: 223/616 - (36%)
• Gaps: 168/616 - (27%)

  Fly    64 GSTHQCDA--VKSYFESIDIKSSGTYS-----------EKGAICGG--NCCNNATELELRDKAAG 113
            |..|..:|  |:|..|:..:..:..||           |...:|..  .||::.||.:|...|..
Mouse    19 GPGHGSEAKVVRSCAETRQVLGARGYSLNLIPPSLISGEHLQVCPQEYTCCSSETEQKLIRDAEV 83

  Fly   114 MFEQLLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEI 178
            .|..|:....|.|...|....::|.....|:..||::....|||..|.|:.....::.:.|::.:
Mouse    84 TFRGLVEDSGSFLIHTLAARHRKFNEFFREMLSISQHSLAQLFSHSYGRLYSQHAVIFNSLFSGL 148

  Fly   179 MNHLIYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQL----FPVAYHQMVHLSKNNLGDLHE 239
                   .:|...:|:           .|::.:..|:.||    ||:.:.|.         ....
Mouse   149 -------RDYYEKSGE-----------GLDDTLADFWAQLLERAFPLLHPQY---------SFPP 186

  Fly   240 DYVNCLQHNFD----EMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTD 300
            |::.||.....    .:.||||.|::::..:.:::..:...:..|.....|:|||..:   .:.:
Mouse   187 DFLLCLTRLTSTADGSLQPFGDSPRRLRLQISRALVAARALVQGLETGRNVVSEALKV---PVLE 248

  Fly   301 TCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTT 365
            .|:..|:::..||.|.|..|     ...|.|:|.||..||.:...  |:..|.|.:|
Mouse   249 GCRQALMRLIGCPLCRGVPS-----LMPCRGFCLNVAHGCLSSRG--LEPEWGGYLD-------- 298

  Fly   366 HILSDTGIINVIKHLQTYF-------------SEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSG 417
                  |::.:.:.||..|             ||.:|....|..::..||.:.||||.  |..|.
Mouse   299 ------GLLLLAEKLQGPFSFELAAESIGVKISEGLMHLQENSVKVSAKVFQECGTPH--PVQSR 355

  Fly   418 EPDARPPPHKNNVKW---ATDPDP----GMVL------FLSTIDKSKEFYTTIVDNFCDEQQH-- 467
            ...|..|..:.:..|   |.:..|    |..|      ....:.:.:.|:..:....|.:.:.
Mouse   356 SRRAPAPREEASRSWRASAEEERPTTAAGTNLHRLVWELRERLSRVRGFWAGLPVTVCGDSRMAA 420

  Fly   468 --SRDDHSCWSGDRFGDYTQLLINPGTDSQRYNPE-------VP-----FNAKAQTGKLNELVDK 518
              |::...||:|...|.|...::....:.|.:|||       ||     .:.:|.|.::.
Mouse   421 DLSQETAPCWTGVGRGRYMSPVVVGSLNEQLHNPELDTSSPDVPTRRRRLHLRAATARMK----- 480

  Fly   519 LFKIRKSIGAAAPSNSIQATHDIQNDMGEGSGGGEGQIGDD----------------------EE 561
                     |||....:. .||...| ..|||||: |..||                      .:
Mouse   481 ---------AAALGQDLD-MHDADED-ASGSGGGQ-QYADDWKAGAVPVVPPARPPRPPRPPRRD 533

  Fly   562 EYGGAHGSGD-----------GSGDGPHTPI 581
            ..|...|||.           ||..|.|||:
Mouse   534 GLGVRGGSGSARYNQGRSRNLGSSVGLHTPL 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dally	NP_001246685.1	Glypican	51..622	CDD:279494	134/616 (22%)
Gpc2	NP_766000.1	Glypican	20..559	CDD:279494	129/608 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	347..382		10/36 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	483..552		16/71 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810