Protein Alignment dally and Gpc6

DIOPT Version :10

• Sequence 1: NP_523983.1
• Gene: dally / 39013
• FlyBaseID: FBgn0263930
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001073313.1
• Gene: Gpc6 / 23888
• MGIID: 1346322
• Length: 565
• Species: Mus musculus
• Alignment Length: 598
• Identity: 138/598 - (23%)
• Similarity: 230/598 - (38%)
• Gaps: 112/598 - (18%)

  Fly    69 CDAVK-SY----FESIDIKSSGTYSEKGAICGG--NCCNNATELELRDKAAGMFEQLLHHHTSSL 126
            |..|: :|    |...||.......|...||..  .||....|.:|..::...||.|:...:..:
Mouse    30 CSEVRQAYGAKGFSLADIPYQEIAGEHLRICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFV 94

  Fly   127 RGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNS 191
            |....:..|:|.....||.:.:|...:.:|.:.|..:...:..:...|:||:..:      ||..
Mouse    95 RTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRY------YTGG 153

  Fly   192 NGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMV----HLSKNNLGDLHEDYVNCLQHNFDEM 252
            |            .||||.:..|:.:|....: |::    |.|        |||:.|:....|::
Mouse   154 N------------VNLEEMLNDFWARLLERMF-QLINPQYHFS--------EDYLECVSKYTDQL 197

  Fly   253 HPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNG 317
            .||||:|::::..:.::...:..|:..|....||.:....:   ..|..|...|:||.|||.|.|
Mouse   198 KPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKV---SPTPGCIRALMKMLYCPYCRG 259

  Fly   318 HHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQT 382
                 ....:.|..||.|||:||.|..|. ||:.|:..:|:: .||...:.....|.:|:..:..
Mouse   260 -----LPTVRPCNNYCLNVMKGCLANQAD-LDTEWNLFIDAM-LLVAERLEGPFNIESVMDPIDV 317

  Fly   383 YFSEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSGEPDARPPPHKNNVKWAT-DPDPGMVLFLST 446
            ..|||||....|..::..||.:.||.|...|   ....||..|...|.::.. :|:........|
Mouse   318 KISEAIMNMQENSMQVSAKVFQGCGQPKPAP---ALRSARSAPENFNTRFRPYNPEERPTTAAGT 379

  Fly   447 -IDK---------------------SKEFYTTIVDNFCDEQQ---HSRDDHSCWSGDRFGDYTQL 486
             :|:                     ||:.::.:....|.:::   .:.::..||:|.....|...
Mouse   380 SLDRLRTVWRTMQHSVTDIKEKLKLSKKVWSALPYTICKDERVTAGTSNEEECWNGHSKARYLPE 444

  Fly   487 LINPGTDSQRYNPEVPFNAKAQTGKLNELVDKLFKIRKSIGAAAPS----NSIQATHDIQNDMGE 547
            ::|.|..:|..||||                       .:....|.    ..|.|...:.|.:..
Mouse   445 IMNDGLTNQINNPEV-----------------------EVDITRPDTFIRQQIMALRVMTNKLKN 486

  Fly   548 GSGGGEGQIGDDEEEYGGAHGSGDGSGDGPHTPIEESEGTTTN----EVESRDSGKTSGSNPLEG 608
            ...|.:....|..:|   :.|||.|||........|.|..||.    :.:.|:. ::|.|.....
Mouse   487 AYNGNDVNFQDTSDE---SSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREE-ESSASKFSSS 547

  Fly   609 TATWMLLTLVTML 621
            ..:|.|:.:|..|
Mouse   548 LISWSLVCMVLAL 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dally	NP_523983.1	Glypican	51..622	CDD:460084	138/598 (23%)
Gpc6	NP_001073313.1	Glypican	23..532	CDD:460084	131/567 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	348..376		6/30 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	490..511		8/23 (35%)