DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dally and C03H12.1

DIOPT Version :9

Sequence 1:	NP_001246685.1	Gene:	dally / 39013	FlyBaseID:	FBgn0263930	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_510583.2	Gene:	C03H12.1 / 181659	WormBaseID:	WBGene00007284	Length:	731	Species:	Caenorhabditis elegans

Alignment Length:	449	Identity:	81/449 - (18%)
Similarity:	154/449 - (34%)	Gaps:	138/449 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 GVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRM-VPSSRMMIHQLYTEIMNHLIYTSNYTNS 191
            ||....:.|      :|..:|:|  |.|.:.:|.:: .|..:......::::..|  |.....|:
Worm   240 GVFRLQSAQ------DLTTLSKN--HDLLTILYFKIKTPPQKFQSASNFSKLAYH--YLDGDPNT 294

  Fly   192 NGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKN-----------NLGDLHEDYVNCL 245
            :     |.|..:.::.:.|.:   :||.  ..|.:|.:|..           .:.::|:|.|...
Worm   295 D-----RTIFCIVTDSQLAAQ---LQLH--NEHDLVLVSSELKLLTTHYKGWVMENVHKDLVKFS 349

  Fly   246 QH----NFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADAL--------YGEQL 298
            |.    |.:.:            |||:..|.:        |.||..::...|        ||...
Worm   350 QEAAMKNVEFL------------NLGRRFHST--------QLAEKFNQGSVLMYFTRDLNYGNAK 394

  Fly   299 TDTCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLV 363
            ....:....:...||..:  ..|..|||.      .|....||....|:|       .::.|.|
Worm   395 YKMFREIAQEYRTCPEKD--FISVDSETP------DNFDLDCSTSLKGIL-------CEANNTL- 443

  Fly   364 TTHILSDTGIINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSGEPDARPPPHKN 428
             :.::.|:.|.|.:........|.::.|:::..|:.:.:|......|:        :.....|.|
Worm   444 -SFMMIDSKIENALAAKYGADREDMVVAINSKQEITRYIKSNITRESI--------NCLIRQHHN 499

  Fly   429 NVKWATDPDPGMVLFLSTIDKSKEFYTTIVDNFCDEQQHSRDDHSCWSGD----RFGDYT-QLLI 488
            :..            .|.:.:|.|..||       :.:..:|.|:...|:    :|.|.| :||:
Worm   500 SAD------------NSFVTESTEIITT-------KTETPKDIHADAVGESSFVKFVDSTAELLL 545

  Fly   489 NPGTDSQRYNPEVPFNAKAQTGKLNELVDKLFKIRKSIGAAAPSNSIQATHDIQNDMGE 547
                                :.|:|.::     ....|..:|.|::|...|.:.|...|
Worm   546 --------------------SRKINVIL-----FMGGIWHSASSSAIAPFHLVANHFKE 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dally	NP_001246685.1	Glypican	51..622	CDD:279494	81/449 (18%)
C03H12.1	NP_510583.2	Thioredoxin_like	119..230	CDD:294274
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10822
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100