Protein Alignment dally and Gpc4

DIOPT Version :9

• Sequence 1: NP_001246685.1
• Gene: dally / 39013
• FlyBaseID: FBgn0263930
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_032176.2
• Gene: Gpc4 / 14735
• MGIID: 104902
• Length: 557
• Species: Mus musculus
• Alignment Length: 647
• Identity: 144/647 - (22%)
• Similarity: 255/647 - (39%)
• Gaps: 130/647 - (20%)

  Fly     8 LAQLLLFTLLCGFVGLSAAKHLDLDGIHHHQHHLHSATTHHRRRLQRDSRAKDAVGGSTHQCDAV 72
            :|:|.|..|||....|||:                        .|..:.::|        .|..|
Mouse     1 MARLGLLALLCTLAALSAS------------------------LLAAELKSK--------SCSEV 33

  Fly    73 KSYFES--IDIKSSGTYSEKG---AICGGN--CCNNATELELRDKAAGMFEQLLHHHTSSLRGVL 130
            :..:.|  .:...:..|...|   .||..:  ||:...|.:...::...|:.::....:.|:.:.
Mouse    34 RRLYVSKGFNKNDAPLYEINGDHLKICPQDYTCCSQEMEEKYSLQSKDDFKTVVSEQCNHLQAIF 98

  Fly   131 ETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNSNGQL 195
            .:..|:|.....||.:.:|...:.:|.|.|..:...:..:...|:.|:..:.:
Mouse    99 ASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYV------------ 151

  Fly   196 GRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQHNFDEMHPFGDIPQ 260
                .|:|  ||||.:..|:.:|.    .:|..| .|:.....::|:.|:....:::.||||:|:
Mouse   152 ----AGNV--NLEEMLNDFWARLL----ERMFRL-VNSQYHFTDEYLECVSKYTEQLKPFGDVPR 205

  Fly   261 QVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNGHHSSSRSE 325
            :::..:.::...:..|...|..|.:|:|:...:   ..|..|...||||.||.:|.|     ...
Mouse   206 KLKLQVTRAFVAARTFAQGLAVARDVVSKVSVV---NPTAQCTHALLKMIYCSHCRG-----LVT 262

  Fly   326 TKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQTYFSEAIMA 390
            .|.||.||.|:||||.|. .|.||..|:..:|:: .:|...:.....|.:|:..:....|:|||.
Mouse   263 VKPCYNYCSNIMRGCLAN-QGDLDFEWNNFIDAM-LMVAERLEGPFNIESVMDPIDVKISDAIMN 325

  Fly   391 AMHNGPELEKKVKKTCGTPSLTP---------YSSGEPDARP--PPHKNNVKWATDPDPGMVLFL 444
            ...|..::.:||.:.||.|...|         .|:.....||  |..:......|..|..:....
Mouse   326 MQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPYHPEQRPTTAAGTSLDRLVTDVK 390

  Fly   445 STIDKSKEFYTTIVDNFCDEQQ-----HSRDDHSCWSGDRFGDYTQLLINPGTDSQRYNPEVPFN 504
            ..:.::|:|::::....|::::     .:.||  ||:|.....|...:...|..:|..||||
Mouse   391 EKLKQAKKFWSSLPSTVCNDERMAAGNENEDD--CWNGKGKSRYLFAVTGNGLANQGNNPEV--- 450

  Fly   505 AKAQTGKLNELVDKLFKIRKSIGAAAPSNSIQATHDIQNDMGEGSGGGEGQIGDDEEEYGGAHGS 569
             :..|.|.:.|:     :|:          |.|...:.:.|.....|.:....|..:|     .|
Mouse   451 -QVDTSKPDILI-----LRQ----------IMALRVMTSKMKNAYNGNDVDFFDISDE-----SS 494

  Fly   570 GDGSGDG---PHTPIE------ESEGTTTNEVESRDSGKTSGSNPLEGTATWMLLTLVTMLF 622
            |:|||.|   ...|.|      :..|.:.||......|..:.:.|       .||..:.:||
Mouse   495 GEGSGSGCEYQQCPSEFEYNATDHSGKSANEKADSAGGAHAEAKP-------YLLAALCILF 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dally	NP_001246685.1	Glypican	51..622	CDD:279494	133/602 (22%)
Gpc4	NP_032176.2	Glypican	26..552	CDD:279494	134/598 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810