Protein Alignment dally and Gpc5

DIOPT Version :10

• Sequence 1: NP_523983.1
• Gene: dally / 39013
• FlyBaseID: FBgn0263930
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_036014229.1
• Gene: Gpc5 / 103978
• MGIID: 1194894
• Length: 626
• Species: Mus musculus
• Alignment Length: 645
• Identity: 160/645 - (24%)
• Similarity: 258/645 - (40%)
• Gaps: 117/645 - (18%)

  Fly    25 AAKHLD-----LDGIHHHQHHLHSATTHHRRRLQRDSRAKD---------AVGGST-----HQCD 70
            :|.||.     |..:....|....||    |..:.|:|...         |:.|||     ..|:
Mouse    44 SATHLPPALPMLGALESEDHSGEGAT----RTPRMDARTWRLGWRCLLLLALLGSTRSEGVESCE 104

  Fly    71 AVKSYFESIDIKSSGTYSEKGAICG------------------GNCCNNATELELRDKAAGMFEQ 117
            .|:..|:         :...||:.|                  ..||....|...:..|....:|
Mouse   105 EVRKLFQ---------WRLGGAVKGLPEAPRAGPDLQVCLSKNPTCCTRKMEERYQIAARQDLQQ 160

  Fly   118 LLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHL 182
            :|...:|:|:.::..||..||..:..|.:.:||.|..||...|..|...:...|.:.:|::..:|
Mouse   161 VLQTSSSTLKLLISRNAAAFQETLETLIRQAENYTSILFCNTYRNMALEAAASIQEFFTDVGLYL 225

  Fly   183 IYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQH 247
            .                  ....|.||.|..||..|||:.|:   ||....:.|....|..|::.
Mouse   226 F------------------GADVNPEEFVNRFFDSLFPLVYN---HLINPGVTDSSLQYSECIRM 269

  Fly   248 NFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYC 312
            ...::.|||:||::|...:|:|:.....|:.||....||::..|.::   .:..|...||||.||
Mouse   270 ARQDVSPFGNIPKRVMGQMGRSLLPGRTFLQALNLGIEVINTTDHIH---FSKECSRALLKMQYC 331

  Fly   313 PNCNGHHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTTHILSDT-----G 372
            |:|     .|...:|.|.|||.||:|||.|.... |:..|...:.||..      |||.     .
Mouse   332 PHC-----QSLMLSKPCMGYCLNVIRGCLAHMTE-LNPHWHAYIRSLEE------LSDAMHGTYD 384

  Fly   373 IINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSGEPDARPPPHKNNVKWATDPD 437
            :.:|:.:.....::|::.|..||.:|..:|...||.|..||..|......|...|:.:|.:....
Mouse   385 VEHVLLNFHLLVNDAVLQAHLNGQKLLDQVNTICGHPVRTPTQSPRCTFDPSKEKHGMKISARNG 449

  Fly   438 PGMVL-----FLSTIDKSKEFYTTIVDNFCDEQQHSRDDHSCWSGDRF-GDYTQLLINPGTDSQR 496
            ...:.     |::::.....||..:.|..|..:..:.:...||:|:.. ..|.|.::..|..:|.
Mouse   450 EETLANRRKEFINSLRLHGSFYGGLADQLCVNELAAPEGRPCWNGEEIVKSYAQRVVGNGIKAQS 514

  Fly   497 YNPEVPFNAKAQTGKLNELVDKLFKIRKSIGAAAPS-NSIQATHDIQNDMGEGSGGG--EGQIGD 558
            .||||  ..:.....:|:::|||..:.:.:...:|. |..:.       :..|||||  |...||
Mouse   515 ANPEV--RVRGTDPVVNQIIDKLKHVIQLLRGRSPKPNKWEL-------LQPGSGGGMLENSSGD 570

  Fly   559 DEEEYGGAHGSGDGSGDGPHTPIEESEGTTTNEVESRDSGKTSGSNPLEG----TATWML 614
            .::|.|   ..|.|||:...| ::.:..:.......:...||.|.....|    |..|:|
Mouse   571 CDDEDG---CGGSGSGEVKRT-LKITNFSCHKTSLEKACHKTKGHQRAGGCVSLTTEWLL 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dally	NP_523983.1	Glypican	51..622	CDD:460084	152/614 (25%)
Gpc5	XP_036014229.1	Glypican	93..592	CDD:460084	142/556 (26%)