Protein Alignment Prm and MYO2

DIOPT Version :9

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_014971.1
• Gene: MYO2 / 854504
• SGDID: S000005853
• Length: 1574
• Species: Saccharomyces cerevisiae
• Alignment Length: 1136
• Identity: 198/1136 - (17%)
• Similarity: 394/1136 - (34%)
• Gaps: 399/1136 - (35%)

  Fly    25 DVNIEYIQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQ 89
            |..|..|.|........|.:.|:....|.:.::.:.:   .|.|.:..|::.:...:|...|:
Yeast   302 DTKINGIDDAKEYKITVDALTLVGITKETQHQIFKIL---AALLHIGNIEIKKTRNDASLSAD-- 361

  Fly    90 FEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDK-AKF 153
             |.|.|...|||.:     |.:..::..|    ||  :|||..::.|..|..::|...||. |||
Yeast   362 -EPNLKLACELLGI-----DAYNFAKWVT----KK--QIITRSEKIVSNLNYSQALVAKDSVAKF 414

  Fly   154 QTEVYELL------------------SQIES------------------------YNKEKIVSE- 175
               :|..|                  .||.|                        |..||:..|
Yeast   415 ---IYSALFDWLVENINTVLCNPAVNDQISSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEF 476

  Fly   176 -KHISKLEVSISELNVKIEEL---------NRTVIDISSHR----SRLSQEN------------- 213
             :|:.|||   .|..|| ||:         |:..||:..::    |.|.:|:
Yeast   477 NQHVFKLE---QEEYVK-EEIEWSFIEFNDNQPCIDLIENKLGILSLLDEESRLPAGSDESWTQK 537

  Fly   214 ------------------------------IELTKDVQD-LKVQLDTVSFSKSQVISQ------- 240
                                          :::..||:. ::...||||....:|:..
Yeast   538 LYQTLDKSPTNKVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNETLI 602

  Fly   241 -----LEDARRRLEDEDR------------------RRSLLESSLHQVEIELDSVRNQLEEESEA 282
                 ||.|.::||:..:                  |:..|.|...|..|||   .|.:...:..
Yeast   603 NILEGLEKAAKKLEEAKKLELEQAGSKKPGPIRTVNRKPTLGSMFKQSLIEL---MNTINSTNVH 664

  Fly   283 RIDLERQLVKANADATSWQ---------------------------NKWNSE------------- 307
            .|    :.:|.|||..:||                           ::|..|
Yeast   665 YI----RCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLRYYILIPHE 725

  Fly   308 ----VAARAEEVEE---------------IRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASE 353
                :..:.|..||               .:.|||:..|:       :..|...|..::...:::
Yeast   726 QWDLIFKKKETTEEDIISVVKMILDATVKDKSKYQIGNTK-------IFFKAGMLAYLEKLRSNK 783

  Fly   354 VEVLIIDLEKS------NNSCRELTKSVNTLEKHNVE---LKSRLDETIILYETSQRDLKNKHAD 409
            :...|:.::|.      .....::::::..|: :|::   ::.|:::          ::|...|.
Yeast   784 MHNSIVMIQKKIRAKYYRKQYLQISQAIKYLQ-NNIKGFIIRQRVND----------EMKVNCAT 837

  Fly   410 LVRTVHELDKVKDN----NNQLTRENKKLGDDL--------HEAKGAINELNRRLHELELELRRL 462
            |::..:....::.|    ...:|...||:..:|        ||...|:. :..::...|...|.|
Yeast   838 LLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEYNAAVT-IQSKVRTFEPRSRFL 901

  Fly   463 ENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLN 527
            ..::|.:..   ::...|:|.:::.::|.||.....|                .|:.|.::|.
Yeast   902 RTKKDTVVV---QSLIRRRAAQRKLKQLKADAKSVNH----------------LKEVSYKLEN-- 945

  Fly   528 ARVIEAETRLKTEVTRIK------KKLQIQITE------------LEMSLDVANK--TNIDLQKV 572
             :|||....|.::|...|      |:||:|:.|            .|..:|:.|:  .:::|||.
Yeast   946 -KVIELTQNLASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHLIDIDNQKSKDMELQKT 1009

  Fly   573 I-----------KKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLA---GLNGELE-EVRSHL 622
            |           |...|:|.::...:::::.:.:..|::....::.|.   .|||:|: ||:|..
Yeast  1010 IENNLQSTEQTLKDAQLELEDMVKQHDELKEESKKQLEELEQTKKTLVEYQTLNGDLQNEVKSLK 1074

  Fly   623 DSANRAKRTVEL---------------QYEEAASRINELTTANVSL----VSIKSKL-----EQE 663
            :...|.:..:.|               .....||..|.:...|..|    :::||:.     ...
Yeast  1075 EEIARLQTAMSLGTVTTSVLPQTPLKDVMGGGASNFNNMMLENSDLSPNDLNLKSRSTPSSGNNH 1139

  Fly   664 LSVVASDYEEVSKELRISDERYQKVQ------VELKHVVEQVHEEQERIVKLETIKKSLEVEVKN 722
            :..::.|.|......:|::|.|:.::      .|:...:.:..|..:..|.::..|:.:....:.
Yeast  1140 IDSLSVDRENGVNATQINEELYRLLEDTEILNQEITEGLLKGFEVPDAGVAIQLSKRDVVYPARI 1204

  Fly   723 LSIRLEEV-ELNAVAGSKRIISKLEARIRDLELELE-------------EEKRRHAETIKILRK- 772
            |.|.|.|: .......|:..::::...|:.:..:|:             ..:..::..:..|..
Yeast  1205 LIIVLSEMWRFGLTKQSESFLAQVLTTIQKVVTQLKGNDLIPSGVFWLANVRELYSFVVFALNSI 1269

  Fly   773 -KERTVKEVLVQCEEDQKNLILLQDAL--DKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELE 834
             .|.|.|..:.  :|:.|..:.|...|  |......|||...|              ::.|::|:
Yeast  1270 LTEETFKNGMT--DEEYKEYVSLVTELKDDFEALSYNIYNIWL--------------KKLQKQLQ 1318

  Fly   835 AAEDRADTAESSLNIIRAKHRTFVTTSTVPG 865
                     :.::|.:       |.:.::||
Yeast  1319 ---------KKAINAV-------VISESLPG 1333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	191/1113 (17%)
MYO2	NP_014971.1	COG5022	2..1567	CDD:227355	198/1136 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910