Protein Alignment Prm and MYO4

DIOPT Version :9

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_009373.1
• Gene: MYO4 / 851204
• SGDID: S000000027
• Length: 1471
• Species: Saccharomyces cerevisiae
• Alignment Length: 940
• Identity: 175/940 - (18%)
• Similarity: 344/940 - (36%)
• Gaps: 278/940 - (29%)

  Fly   101 LKLRKLLEDVHLESEETTL-----------------LLKKKHNEIITDFQEQVEILTKNKARAEK 148
            ::::....|..|.|||..|                 ::||   :|:|..::.|..|..|:|...:
Yeast   346 IEMKMTRNDASLSSEEQNLQIACELLGIDPFNFAKWIVKK---QIVTRSEKIVTNLNYNQALIAR 407

  Fly   149 DK-AKF------------------------QTEVYELLSQIESYNKEKIVSEKHISKLEVSISEL 188
            |. |||                        |..|:..:..::.|..|..  ||: |..:..|:..
Yeast   408 DSVAKFIYSTLFDWLVDNINKTLYDPELDQQDHVFSFIGILDIYGFEHF--EKN-SFEQFCINYA 469

  Fly   189 NVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDR 253
            |.|:::      :.:.|..:|.||  |..|:    :::...:.||.:|...
Yeast   470 NEKLQQ------EFNQHVFKLEQE--EYVKE----EIEWSFIEFSDNQPCI-------------- 508

  Fly   254 RRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKW--------NSEVAA 310
              .|:|:.|        .:.:.|:|||.         :.:.:| .||.:|.        ::||.:
Yeast   509 --DLIENKL--------GILSLLDEESR---------LPSGSD-ESWASKLYSAFNKPPSNEVFS 553

  Fly   311 --RAEEVEEIRRKYQVRITELEEHIESLI------VKVNNLEKMKTRLASEVEVLIIDLEKSNNS 367
              |..:.:.|...|.|   ::|..:|..|      |.:.:|:..|. ..:.:...|:|
Yeast   554 KPRFGQTKFIVSHYAV---DVEYEVEGFIEKNRDSVSLGHLDVFKA-TTNPIFKQILD------- 607

  Fly   368 CRELTKSVNTLEKHNVELKSRLDETIILYETSQRD------LKNKHADLV-----RTVHELDKVK 421
            .||| :|.:..|:.|.|.|     .:|....||:.      .|....:|:     ..||.:..:|
Yeast   608 NREL-RSDDAPEEQNTEKK-----IMIPARLSQKKPTLGSMFKKSLGELMAIINSTNVHYIRCIK 666

  Fly   422 DNN-------------NQL----TRENKKLGDDLHEAKGAINELNRR-------------LHELE 456
            .|:             :||    ..|..::......::...:|..:|             |:..:
Yeast   667 PNSEKKPWEFDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLTDYSLWSGILYNPD 731

  Fly   457 LELRRLENERDEL-------TAAYKEA------EAGRKA--EEQRGQRLAADFNQYRHDAERRLA 506
            |....:.|....:       :|.|:..      :||..|  |:.|..::    |:.....::::.
Yeast   732 LPKEAIVNFCQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTNKM----NEICIIIQKKIR 792

  Fly   507 EKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEV-TRIKKKLQIQITEL--------------- 555
            .:...::.::...||:..|...|.:...||:..|: ||....||..|..|
Yeast   793 ARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKREYYRAAIGQIIK 857

  Fly   556 -------EMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQ---LQATLDQYAVAQRRLAG 610
                   ::.||..|:..:.:..||.:..::....:..|..::|.   :|:.: :..:|:||...
Yeast   858 LQCTCKRKLILDSVNRKFMLMAAVIIQSYIRSYGHKTDYRTLKRSSILVQSAM-RMQLARRRYIV 921

  Fly   611 LNGELEE--VRSH-----LDSANRAKRTVELQYE---EAASRINELTTANVSLVSIKSKLEQELS 665
            |..|:||  :|:.     |:.|...|.:..|..|   ::.:|:.:|...::|  :|.||..||..
Yeast   922 LQKEVEERNIRASYGIGLLEEAIEFKNSFILNLEMLNDSYTRLTQLLQGDLS--NIPSKQRQEYE 984

  Fly   666 VVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEV 730
            .:.:.|.:...:|:       .:|||:.:.:.:.:..:||..|..::            |:....
Yeast   985 TIVNGYNDKISKLK-------TLQVEIMNTLNKKNALKERKKKQSSL------------IQSHMQ 1030

  Fly   731 ELNAVAGSKRIISKLEARIRDLELEL---EEEKRRHAETIKILRKKERT---------VKEVLVQ 783
            .|.|:.|:|.  |:|...::.::.||   |....:...|.....|.::.         ||..||.
Yeast  1031 SLAAIKGNKP--SRLSDEVKSMKQELAFIENVIAQDFTTTYSANKNDKVKGLGIAGQQVKPKLVN 1093

  Fly   784 -CEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSL 847
             ...:..|..||:..:|     :|.|..:::|             .:.:::...|...|.....:
Yeast  1094 VIRRESGNPDLLELLMD-----LNCYTLEVTE-------------GYLKKVNVTEVNGDNVLGPI 1140

  Fly   848 NIIRAKHRTFVTTSTVPGSQVYIQETTRTI 877
            ::|.....:.|....:..|..:|.:...|:
Yeast  1141 HVITTVVSSLVRNGLLIQSSKFISKVLLTV 1170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	171/914 (19%)
MYO4	NP_009373.1	COG5022	2..1471	CDD:227355	175/940 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910