Protein Alignment Prm and IMH1

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_013412.1
• Gene: IMH1 / 851018
• SGDID: S000004300
• Length: 911
• Species: Saccharomyces cerevisiae
• Alignment Length: 913
• Identity: 200/913 - (21%)
• Similarity: 364/913 - (39%)
• Gaps: 254/913 - (27%)

  Fly    30 YIQDLSSLSRLEDKIRLLQDDLEVERELRQRIE-REKADLSVQVIQMSERLEEAEGGAEHQF--- 90
            :.|||:      :|..||.|  |::|..:|..| .|.|.        ||.|::    .|.:|
Yeast   101 FFQDLN------NKNNLLND--EIKRLTKQNSEIPESAS--------SETLKD----KEEEFLKK 145

  Fly    91 EANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQV---EILTKNKARAEKDKAK 152
            |.|.|.|.:  .|:|.:|.:::|.:    .::|:.|:.::..:|::   |.:.|.:..|:|.|.
Yeast   146 EQNYKNDID--DLKKKMEALNIELD----TVQKEKNDTVSGLREKIVALENILKEEREAKKQKE- 203

  Fly   153 FQTEVYELLSQIESYNKEKIVSEKHISKLEVSIS--------------ELNVKIEELNRTVIDIS 203
             :..:.||..::...|.....|...|::||.::|              |||:.::|..|.:.::.
Yeast   204 -EVSISELKEELAIKNHSLEDSRMKITELEQNLSSKSTIMEEKSSELAELNITLKEKERKLSELE 267

  Fly   204 SHRSRL----SQENI-------------------------------------------------- 214
            .....|    |.:|:
Yeast   268 KKMKELPKAISHQNVGNNNRRKKNRNKGKKNKGGITTGDISEEETVDNSINTEEYDKLKENLQEL 332

  Fly   215 -ELTKDVQDLKVQLDTVSF----SKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRN 274
             |..||.:|.|.:.:.:..    :|....||||.:.:.||..:......:.||.:...||:.||:
Yeast   333 QEKYKDCEDWKQKYEDIEAELKDAKELENSQLEKSAKELETLNTELIDTKKSLKEKNSELEEVRD 397

  Fly   275 QLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRK-------YQVRITELEEH 332
            .|.       .:..:||.|..:.....:|.|.||.....|::::|.|       |:.:.|||...
Yeast   398 MLR-------TVGNELVDAKDEIKESSSKQNEEVKTVKLELDDLRHKNATMIEAYEAKNTELRSK 455

  Fly   333 IESLIVKVNNL-----EKMKTRLASE-------VEVLIIDLEKSNNSCRELTKSVNTLEKHNVEL 385
            ||.|..||.:|     ||.|.:..|:       .|:..:..||||.: :||| |:.|..|...:.
Yeast   456 IELLSKKVEHLKNLCTEKEKEQTTSQNKVAKLNEEISQLTYEKSNIT-KELT-SLRTSYKQKEKT 518

  Fly   386 KSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNR 450
            .|.|:|.:..: :.|:|:..|..:.:|..|.  |:.:..:.|.:||:.|.:|:.:...:..|..:
Yeast   519 VSYLEEQVKQF-SEQKDVAEKSTEQLRKDHA--KISNRLDLLKKENETLHNDIAKNSNSYEEYLK 580

  Fly   451 RLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEI-EA 514
            ...:|...|..|:.:.:.|                  |.:.::.|::....:|:..|.:.:: |:
Yeast   581 ENGKLSERLNILQEKYNTL------------------QNVKSNSNEHIDSIKRQCEELNVKLKES 627

  Fly   515 IRKQTSIEIEQLN--ARVIEAETRLKTEVTRIKKKLQIQIT----ELEMSL----DVANK--TNI 567
            .:|..|:| ::||  |.:::.:||....:.|:....|...:    |||..|    |..||  ..:
Yeast   628 TKKILSLE-DELNEYANIVQDKTREANTLRRLVSDSQTDDSSKQKELENKLAYLTDEKNKLEAEL 691

  Fly   568 DLQKVIKKQSLQ-----LTELQAHY---------------------EDVQRQLQATLDQYAVAQR 606
            |||...|...||     :|||::..                     .|::|:.|||.|.
Yeast   692 DLQTSRKATELQEWKHTVTELKSEIHALKLREEGLKSEVDALKHVNNDIKRKTQATSDD------ 750

  Fly   607 RLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDY 671
                 :.:||::.|:|          :|...:|..:..||.:||..|:::.::|.::...:..:|
Yeast   751 -----SDQLEQITSNL----------KLSLSKADEKNFELQSANEKLLNLNNELNKKFDRLLKNY 800

  Fly   672 EEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVA 736
            ..:|.:|....||             |..::..|:.:..:|.            .|....:::..
Yeast   801 RSLSSQLNALKER-------------QYSDKSGRVSRSGSIG------------TLANANIDSSP 840

  Fly   737 GSKRIISKLEARIRDLELELEEEKRRHAETIK-----ILRKKER-----TVKEVLVQCEE-DQKN 790
            .:....:|||.......|||:.||......||     .|..||:     .|..:|:|.:. |:|.
Yeast   841 ANNSNPTKLEKIRSSSSLELDSEKNEKIAYIKNVLLGFLEHKEQRNQLLPVISMLLQLDSTDEKR 905

  Fly   791 LIL 793
            |::
Yeast   906 LVM 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	198/909 (22%)
IMH1	NP_013412.1	SMC_prok_B	42..>734	CDD:274008	154/691 (22%)
		GRIP	865..906	CDD:460221	10/40 (25%)