DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prm and XIE

DIOPT Version :9

Sequence 1:	NP_523982.2	Gene:	Prm / 39002	FlyBaseID:	FBgn0003149	Length:	879	Species:	Drosophila melanogaster
Sequence 2:	NP_175858.1	Gene:	XIE / 841898	AraportID:	AT1G54560	Length:	1529	Species:	Arabidopsis thaliana

Alignment Length:	898	Identity:	160/898 - (17%)
Similarity:	327/898 - (36%)	Gaps:	261/898 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 SVQVIQMSERLEEA----------EGGAE----HQFEANRKRD----------AELLKLR-KLLE 108
            ::.::.|||:.:||          .|..|    .:.:::..:|          ||||... |.||
plant   308 AMDIVGMSEKEQEAIFRVVAAILHLGNVEFTKGKEVDSSVPKDDKSKFHLNTVAELLMCDVKALE 372

  Fly   109 D-----VHLESEETTL--------------LLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQ 154
            |     |.:..||...              |.|..::.:.....|::.:.....|.:.
plant   373 DALCKRVMVTPEEVIKRSLDPQSALISRDGLAKTIYSRLFDWLVEKINVSIGQDATSR------- 430

  Fly   155 TEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTK- 218
                .|:..::.|..|   |.|..|..:..|:..|.|:::      ..:.|..::.||  |.||
plant   431 ----SLIGVLDIYGFE---SFKTNSFEQFCINFTNEKLQQ------HFNQHVFKMEQE--EYTKE 480

  Fly   219 ----------DVQDLKVQLDTVSFSKSQVISQLED------------ARRRLEDEDRRRSLLESS 261
                      |.||:   ||.:......:::.|::            |.:..:.....:..::..
plant   481 AIDWSYIEFVDNQDV---LDLIEKKPGGIVALLDEACMFPKSTHETFANKLYQTFKTHKRFIKPK 542

  Fly   262 LHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWN---------SEVAARAEEVEE 317
            |.:.:..:.....:::.:|:..:|..:..|..........:|..         .|..:::.:...
plant   543 LSRTDFAVAHYAGEVQYQSDLFLDKNKDYVIPEHQDLLGASKCPFVVGLFPPLPEETSKSSKFSS 607

  Fly   318 IRRKYQVRITELEEHIESL------IVKVNNLEK----------MKTRLASEVEVLIIDLEKSNN 366
            |..::::::.:|.|.:.|.      .||.|||.|          .:.|....:|.:.|
plant   608 IGSRFKLQLQQLMETLNSTEPHYIRCVKPNNLLKPAVFENVNIMQQLRCGGVLEAIRI------- 665

  Fly   367 SC------RELTKSVNTL-------------EK-------HNVELK----------------SRL 389
            ||      :...:.:|..             ||       .|:.||                :.|
plant   666 SCAGYPTRKPFFEFINRFGLLYPRALEGNYEEKAAAQKILDNIGLKGYQVGKTKVFLRAGQMAEL 730

  Fly   390 D--ETIILYETS---QRDLKNKHADLVRTVHELDKVKDNNNQLTRE--NKKLGDDLHEAKGAINE 447
            |  .|::|...:   ||.::...|.  |....|.|...:...|.|.  :.|:.|:|.....|:
plant   731 DARRTMVLSAAAKKIQRRIRTHQAQ--RRFILLRKATISLQALCRGRLSSKIFDNLRRQAAAV-- 791

  Fly   448 LNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEI 512
                  :::...|||.:.:     :||........ .|.|.|..|...|:|.   |:..:....|
plant   792 ------KIQKNARRLHSRK-----SYKNLHVAALV-VQTGLRAMAAHKQFRF---RKQTKAATTI 841

  Fly   513 EAIRK--QTSIEIEQLNARVIEAETRLKTEVTR------------------IKKKLQIQITELEM 557
            :|..:  :.::..::|...||.::||.:.::.|                  .|..|:.::.||..
plant   842 QAQFRCHRATLYFKKLKKGVILSQTRWRGKLARRELRQLKMASRETGALKEAKDMLEKKVEELTY 906

  Fly   558 SLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNG----ELEEV 618
            ...:..::.:||:   ::::.::.:||:..|::::::..|              ||    |.|..
plant   907 RAQLEKRSRVDLE---EEKNQEIKKLQSSLEEMRKKVDET--------------NGLLVKEREAA 954

  Fly   619 RSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDE 683
            :..::.|.......::..|: ..:|..||.   .:..:|:.||||.........:..:....|::
plant   955 KKAIEEAPPVVTETQVLVED-TQKIEALTE---EVEGLKANLEQEKQRADDATRKFDEAQESSED 1015

  Fly   684 RYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVEL---NAVAGSKRIISK- 744
            |.:|    |:...::..:.||.:.:||  :|...:|.:|..:|.:.|.:   ..::|..|.|.:
plant  1016 RKKK----LEDTEKKAQQLQESVTRLE--EKCNNLESENKVLRQQAVSIAPNKFLSGRSRSILQR 1074

  Fly   745 --------LEARIRDLELELEEEKRRHAETI-----KILRKKERTVKEVLVQC 784
                    ::|| ..|:|......||....:     |.|.:|::..:|:|::|
plant  1075 GSESGHLSVDAR-PSLDLHSHSINRRDLSEVDDKPQKSLNEKQQENQELLIRC 1126

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	160/898 (18%)
XIE	NP_175858.1	Myosin_N	14..51	CDD:280832
		MYSc	66..734	CDD:214580	74/457 (16%)
		MYSc_Myo11	79..723	CDD:276835	72/446 (16%)
		type_I_hlyD	723..>980	CDD:130902	53/293 (18%)
		ApoLp-III_like	<889..1026	CDD:304399	28/161 (17%)
		TPR_MLP1_2	907..1054	CDD:285204	32/173 (18%)
		bZIP	<1016..1052	CDD:304365	10/41 (24%)
		MyosinXI_CBD	1114..1495	CDD:271259	4/13 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910