DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prm and XIA

DIOPT Version :9

Sequence 1:	NP_523982.2	Gene:	Prm / 39002	FlyBaseID:	FBgn0003149	Length:	879	Species:	Drosophila melanogaster
Sequence 2:	NP_171954.1	Gene:	XIA / 839480	AraportID:	AT1G04600	Length:	1730	Species:	Arabidopsis thaliana

Alignment Length:	856	Identity:	188/856 - (21%)
Similarity:	324/856 - (37%)	Gaps:	232/856 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 LESEETTLLLKKKHNEIIT--------------DFQEQVEILTKNKARAEKDK------------ 150
            :::::...|::||...||.              .|.:::....||..|..|.|
plant   486 IDNQDVLDLIEKKPGGIIALLDEACMFPRSTHDTFAQKLYQTFKNHKRFGKPKLAQTDFTICHYA 550

  Fly   151 --AKFQTEVYELLSQIESYNKEKIVSEKHISKLEVS----ISELNVKIEELNRTVIDISSHRSRL 209
              ..:|||::  |.:    ||:.:|.| |.:.|..|    :|.|...:.|       .||..|:.
plant   551 GDVTYQTELF--LDK----NKDYVVGE-HQALLSSSDCSFVSSLFPPLPE-------ESSKTSKF 601

  Fly   210 SQENIELTKDVQDLKVQLDTVS-----------------FSKSQVISQL------EDAR------ 245
            |....:..:.:|.|...|.|..                 |....::.||      |..|
plant   602 SSIGSQFKQQLQSLLESLSTTEPHYIRCVKPNNLLKPDIFENINILHQLRCGGVMEAIRISCAGY 666

  Fly   246 --RRLEDE--DRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLE-----RQLVKANADATSWQ 301
              |:..:|  .|.|.|...:......|:|:.:..|     |::||:     :..|...|...:..
plant   667 PTRKPFNEFLTRFRILAPETTKSSYDEVDACKKLL-----AKVDLKGFQIGKTKVFLRAGQMAEM 726

  Fly   302 NKWNSEVAARAEEV-------EEIRRKY---QVRITELEEHIESLIVKVNNLEKMKTRLASEVEV 356
            :...:||...:..:       .:.|:|:   |...||::......:.:| ..|.|:...||
plant   727 DAHRAEVLGHSARIIQRNVLTYQSRKKFLLLQAASTEIQALCRGQVARV-WFETMRREAAS---- 786

  Fly   357 LIIDLEKS------NNSCRELTKSVNTLE--------KHNVELKSRLDETIILYETSQRDLKNKH 407
              :.::|.      .|:.:.|..|..:::        :..::|:.:...|||:....:|.|  .|
plant   787 --LRIQKQARTYICQNAYKTLCSSACSIQTGMRAKAARIELQLRKKRRATIIIQSQIRRCL--CH 847

  Fly   408 ADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAI-NELNRRLHELELELRRLENERDELTA 471
            ...|||                           .|.|| .:...|:.....|||.|:       .
plant   848 QRYVRT---------------------------KKAAITTQCGWRVKVARRELRNLK-------M 878

  Fly   472 AYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEA---IRKQTSIEIEQLNARVIEA 533
            |.||..|                   ..||:.:|..:.||:.:   :.||..:|||:..::.|||
plant   879 AAKETGA-------------------LQDAKTKLENQVEELTSNLELEKQMRMEIEEAKSQEIEA 924

  Fly   534 ETRLKTEVTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQL-----------TELQAHY 587
            ...:.|::     |||::.|:...|.:::     |||.|:....|||           ::||:..
plant   925 LQSVLTDI-----KLQLRDTQETKSKEIS-----DLQSVLTDIKLQLRDTQETKSKEISDLQSAL 979

  Fly   588 EDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVS 652
            :|:|.::: .|.:.......||..|.:|:|..|.|.  |:...: |.:|||.:....|.....|.
plant   980 QDMQLEIE-ELSKGLEMTNDLAAENEQLKESVSSLQ--NKIDES-ERKYEEISKISEERIKDEVP 1040

  Fly   653 LVS----IKSKLE-QELSVVASDYEEVSKEL-RISDERYQKVQVELKHVVEQVHEEQERIVKLET 711
            ::.    ||.:.| |:|..:.|..||...|| |..||....:..:||   |.|..:.|.:..||.
plant  1041 VIDQSAIIKLETENQKLKALVSSMEEKIDELDRKHDETSPNITEKLK---EDVSFDYEIVSNLEA 1102

  Fly   712 IKKSLEVEVKNLSIRLEEVELNAVAGSK--RIISKLEARIRDLELE------LEEEKRRHAETIK 768
            ..:.|:..|.:|..::.|...|:....:  :.|.|.|:...|..::      |.:|.:...:.:.
plant  1103 ENERLKALVGSLEKKINESGNNSTDEQEEGKYILKEESLTEDASIDNERVKKLADENKDLNDLVS 1167

  Fly   769 ILRKK----ERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGVS-QQTTTRVRR 828
            .|.||    |:..:|....|||      .|:.|||..|..|::.......:|.|| .:|..::||
plant  1168 SLEKKIDETEKKYEEASRLCEE------RLKQALDAETGLIDLKTSMQRLEEKVSDMETAEQIRR 1226

  Fly   829 FQRELEAAEDR 839
            .|..:.:|..|
plant  1227 QQALVNSASRR 1237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	188/856 (22%)
XIA	NP_171954.1	Myosin_N	11..47	CDD:280832
		MYSc	59..727	CDD:214580	51/259 (20%)
		MYSc_Myo11	75..719	CDD:276835	50/251 (20%)
		SPEC	869..1036	CDD:295325	52/206 (25%)
		TACC	974..1189	CDD:282818	56/221 (25%)
		MyosinXI_CBD	1278..1699	CDD:271259
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910