DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prm and XIJ

DIOPT Version :9

Sequence 1:	NP_523982.2	Gene:	Prm / 39002	FlyBaseID:	FBgn0003149	Length:	879	Species:	Drosophila melanogaster
Sequence 2:	NP_001319790.1	Gene:	XIJ / 824985	AraportID:	AT3G58160	Length:	1242	Species:	Arabidopsis thaliana

Alignment Length:	869	Identity:	161/869 - (18%)
Similarity:	312/869 - (35%)	Gaps:	235/869 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 LESEETTLLLKKKHNEIIT--------------DFQEQVEILTKNKARAEKDK--------AKFQ 154
            :::::...|::||...||.              .|.|::....|:..|..|.|        ..:.
plant   485 VDNKDVVDLIEKKPGGIIALLDEACMLPKSTPETFSEKLYHTFKDHKRFMKPKLTRSDFTLVHYA 549

  Fly   155 TEVYELLSQIESYNKEKIVSE---------------------KHISKLEVSI--SELNVKIEELN 196
            .:|.....|....||:.:|:|                     |..||.:.|.  :...:::::|.
plant   550 GDVQYQSDQFLDKNKDYVVAEHQDLLNASKCSFVSGLFPPLPKESSKSKFSSIGARFKLQLQQLM 614

  Fly   197 RTVIDISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKSQVISQ------LEDARRRLEDEDRRR 255
            .|:.....|..|..:.|..|...|           |..:.|:.|      ||..|.:.......|
plant   615 ETLNSTEPHYIRCVKPNNLLQPTV-----------FDNANVLHQLRSGGVLEAIRVKCAGYPTNR 668

  Fly   256 SLLESSLHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRR 320
            :.:|.....:.:..:.::.:.|.|...:..||::      ..|.:| ...|:|..||.::.|:..
plant   669 TFIEFLNRFLILAPEILKGEYEAEVACKWILEKK------GLTGYQ-IGKSKVFLRAGQMAELDA 726

  Fly   321 KYQVRITELEEHIESLIVKVNNLEKMKTRLASEVEVLI------IDLEKSNNSCRELTKSVNTLE 379
            .....:.|....|:.         :::|||..|..||:      |......|..|:::|.:.. |
plant   727 HRTRVLGESARMIQG---------QVRTRLTRERFVLMRRASVNIQANWRGNIARKISKEMRR-E 781

  Fly   380 KHNVELKSRLDETIILYETSQRDL-KNKHADL-----VRTV---HELDKVKDNNNQLTRENKKLG 435
            :..::::..|...|     :::|. |.|.:.|     |||:   ||.      ..:||.....:.
plant   782 EAAIKIQKNLRRQI-----AKKDYGKTKSSALTLQSGVRTMAARHEF------RYKLTTRAATVI 835

  Fly   436 DDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHD 500
            ........||::..:        |:|       ::...|....||.|.:|.||...||
plant   836 QAYWRGYSAISDYKK--------LKR-------VSLLCKSNLRGRIARKQLGQSKQAD------- 878

  Fly   501 AERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITELEMSLDVANKT 565
                   :.||.|   |:..:|:.......::....|.:|          |..:.|.......|.
plant   879 -------RKEETE---KERKVELSNRAEEAVDMSFVLHSE----------QSDDAESGHGRKAKL 923

  Fly   566 NIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKR 630
            :|:.:..:.|.|:..:| |:..|::..:.:..|               .:|....|.|.::
plant   924 SIESEDGLDKSSVLHSE-QSDDEELGHERKTKL---------------SIESEDGHSDQSD---- 968

  Fly   631 TVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHV 695
            ..|:::|.....          .:..:..:|:.. |:.||.   |.:..|..:|..|..::.:..
plant   969 DEEIEHERKTKH----------CIQAEDGIEKSY-VMHSDQ---SDDEEIGHKRKTKHSIQAEDG 1019

  Fly   696 VEQ---VHEEQ---ERIVKLETIKKSLEVE--VKNLSIRLEEVELNAVAGSKRIISKLEARIRDL 752
            :|:   ||.:|   |.|......|.:::||  ::...:...|...|..:    ::|::.:.|||.
plant  1020 IEKSFVVHSDQSDDEEIGHERKTKHAIQVEDGIQKSFVTCSEKPYNTFS----VVSQITSPIRDT 1080

  Fly   753 ELE------------LEEEK-------RRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDAL 798
            |:|            |:.||       |:.||..::..::.:       :.||.::.:..|||:|
plant  1081 EIESLTAEVEMLKALLQVEKQRADISERKCAEARELGERRRK-------RLEETERRVYQLQDSL 1138

  Fly   799 DKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRTFVTTSTV 863
            ::....::   .|.|:.:.:.:..:.............:|.||::|:|.........||...|
plant  1139 NRLLYSMS---DQFSQLKSILRSPSMSASTMASAPVVRDDLADSSENSEASSSDSDFTFPAPS-- 1198

  Fly   864 PGS-----------QVYIQETTRT 876
            |.|           ||.:|:.:.|
plant  1199 PSSDNFSTFNPNQLQVIVQDLSTT 1222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	152/833 (18%)
XIJ	NP_001319790.1	Myosin_N	9..46	CDD:397036
		MYSc_Myo11	74..717	CDD:276835	44/249 (18%)
		IQ	829..849	CDD:197470	2/19 (11%)
		DUF460	<1081..>1142	CDD:421465	14/67 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910