DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prm and ATM1

DIOPT Version :9

Sequence 1:	NP_523982.2	Gene:	Prm / 39002	FlyBaseID:	FBgn0003149	Length:	879	Species:	Drosophila melanogaster
Sequence 2:	NP_001154628.2	Gene:	ATM1 / 821534	AraportID:	AT3G19960	Length:	1176	Species:	Arabidopsis thaliana

Alignment Length:	1008	Identity:	177/1008 - (17%)
Similarity:	343/1008 - (34%)	Gaps:	357/1008 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SSKYSYRATS--TGPG---TADVNIEYIQDLSSLSRLEDKI-------------RLLQDDLE--- 52
            |..||..::|  :|.|   ||.:.::|:..|...|.:|.:|             :.|::|..
plant   262 SMTYSISSSSGESGAGKTETAKIAMQYLAALGGGSGIEYEILKTNPILEAFGNAKTLRNDNSSRF 326

  Fly    53 ---VERELRQRIEREKADLSVQVIQMSERLEEAEG------------------------------ 84
               :|....:..:...|.:...:::.|..::.|||
plant   327 GKLIEIHFSESGKISGAQIQTFLLEKSRVVQCAEGERSYHIFYQLCAGASPALREKLNLTSAHEY 391

  Fly    85 ---GAEHQFEANRKRDAELL-KLRKLLEDVHLESEET------------------TLLLKKKHNE 127
               |..:.:..|...|||.. .:::.|:.||:..|:.                  |::..:.|.|
plant   392 KYLGQSNCYSINGVDDAERFHTVKEALDIVHVSKEDQESVFAMLAAVLWLGNVSFTVIDNENHVE 456

  Fly   128 IITD----------------------------------FQEQVEILTKNKARAEKD--------- 149
            .:.|                                  ..|....|:|...|...|
plant   457 PVADESFLFHSLGSWCWKQECLLHNMCLSTVAKLIGCNINELTLTLSKRNMRVRNDTIVQKLTLP 521

  Fly   150 -----KAKFQTEVYELLSQ--IESYNKEKIVSEKHISKLEVSISELNV-KIEELNRTVID---IS 203
                 :......:|..|..  :|..||...|.::...:   |||.|:: ..|..::...:   |:
plant   522 QAIDARDALAKSIYSCLFDWLVEQINKSLAVGKRRTGR---SISILDIYGFESFDKNSFEQFCIN 583

  Fly   204 SHRSRLSQE------NIELTKDVQDLKVQLDTVSFSKSQ------------VISQLED------- 243
            ....||.|.      .:|..:.:|| .:....|.|..:|            ::|.|::
plant   584 YANERLQQHFNRHLFKLEQEEYIQD-GIDWTRVDFEDNQNCLSLFEKKPLGLLSLLDEESTFPNG 647

  Fly   244 --------ARRRLEDE----------------------------DRRRSLLESSLHQVEIELDSV 272
                    .::.|:..                            ::.|.||.|...|:   |.|.
plant   648 TDLTLANKLKQHLQSNSCFRGDKGKLFTVVHYAGEVTYETTGFLEKNRDLLHSDSIQL---LSSC 709

  Fly   273 RNQLEE--ESEARIDLERQLV-------KANADATSWQNKWNSEVAARAEEVEEIRRKYQV--RI 326
            ...|.:  .|...|..|:.:|       .|::...|...|:.|::             :|:  |:
plant   710 SCLLPQAFASSMLIQSEKPVVGPLYKAGGADSQRLSVATKFKSQL-------------FQLMQRL 761

  Fly   327 TELEEHIESLIVKVNNLEK----------MKTRLASEVEVLIIDLEKSNNSCRELTKS---VNTL 378
            .....|....| |.||::.          .:.|....:|||          |:...|.   :..|
plant   762 GNTTPHFIRCI-KPNNIQSPGVYEQGLVLQQLRCCGVLEVL----------CKGPYKRFFIIAIL 815

  Fly   379 EKHNV--ELKSRLDETIILYETSQ----RDLKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDD 437
            .:.|:  |: .::..|.:.:.|.|    .|.:|      ||:|.:.:|:.:...
plant   816 HQFNILPEM-YQVGYTKLFFRTGQIGVLEDTRN------RTLHGILRVQSSFRG----------- 862

  Fly   438 LHEAKGAINELNRRLHELELELR--RLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHD 500
             ::|:..:.||.|.:..|:..:|  ::..|..||...:|.|...:...:.:..|:     ||:..
plant   863 -YQARCLLKELKRGISILQSFVRGEKIRKEFAELRRRHKAAATIQSQVKSKIARI-----QYKGI 921

  Fly   501 AE--------------RRLA----------EKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEV 541
            |:              ||.:          .|..|:..:..:.|: :.:|..||::||..|:
plant   922 ADASVVIQSAIRGWLVRRCSGDIGWLKSGGAKTNELGEVLVKASV-LSELQRRVLKAEAALR--- 982

  Fly   542 TRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQR 606
                        |.|...|:..:.   ||:...:.|...|::::..|..|:|:::.....::|::
plant   983 ------------EKEEENDILQQR---LQQYENRWSEYETKMKSMEEIWQKQMRSLQSSLSIAKK 1032

  Fly   607 RLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDY 671
            .||     :|:...:.|::..|....:  ::.::::....|:..|.  |....:...|||:.
plant  1033 SLA-----VEDSARNSDASVNASDATD--WDSSSNQFRSQTSNGVG--SRLQPMSAGLSVIG--- 1085

  Fly   672 EEVSKELRISDERYQKVQV---ELKHVVE----QVHEEQERIVKLETIKKSLEVEVKNLSIRLEE 729
                   |:::|..|:.||   :.|.:||    ||....:...:|..:|:..|...|:...||.|
plant  1086 -------RLAEEFEQRAQVFGDDAKFLVEVKSGQVEANLDPDRELRRLKQMFETWKKDYGGRLRE 1143

  Fly   730 VELNAVAGSKRIISKLEARIRDLELELEEEKRR 762
            .:|        |:|||.:  .:....:|:.||:
plant  1144 TKL--------ILSKLGS--EESSGSMEKVKRK 1166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	168/978 (17%)
ATM1	NP_001154628.2	MYSc	160..847	CDD:214580	99/616 (16%)
ATM1	NP_001154628.2	MYSc_Myo8	179..835	CDD:276834	96/604 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910