Protein Alignment Prm and Myo28B1

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Alignment Length: 1015
• Identity: 180/1015 - (17%)
• Similarity: 328/1015 - (32%)
• Gaps: 359/1015 - (35%)

  Fly    29 EYIQDLSSLSRLEDK--IRLLQD------------------------DLEVERELRQRIEREKAD 67
            |.::|:.:|..|::.  :|.||:                        .:...||::....:..|:
  Fly    67 EDVEDMITLGDLQEYTILRNLQNRYAKQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAE 131

  Fly    68 LSVQVIQMS-------ERLEE-------AEGGAEHQFEANRKRDAELLKLRKLLEDVHLESEETT 118
            |...:..:|       :||:|       .|.||.                         ::|.|.
  Fly   132 LPPHIFAISDNAFQRLQRLKENQCVVISGESGAG-------------------------KTESTK 171

  Fly   119 LLLK------KKH----------NEIITDFQEQVEILTKNKAR---------------------- 145
            |:|:      .||          |.|:..|.....:...|.:|
  Fly   172 LILQYLAAISGKHSWIEQQIIEANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQ 236

  Fly   146 --AEKDKAKFQTE-------VYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVID 201
              .||.:..||:.       .|.:|:.:.:..:|::                  |::|.:.:...
  Fly   237 YLLEKSRIVFQSRDERNYHIFYCMLAGLSTAERERL------------------KLQEQSPSQYH 283

  Fly   202 ISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVE 266
            ..:.....:.......||..|::..:..:||...:|.|.|              |||.:.||
  Fly   284 YLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSIL--------------SLLAAILH--- 331

  Fly   267 IELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEE 331
              |.::|....|.:        .|..|..|.|              ..::.:.:...:.|:.|..
  Fly   332 --LGNLRFTATEVA--------NLATAEIDDT--------------PNLQRVAQLLGIPISALNA 372

  Fly   332 HIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILY 396
            .:....:.|:. |.:.|.|:.|..:     |..:...:.|...:      .|.:..|::|||
  Fly   373 ALTQRTIFVHG-EHVTTSLSKEAAI-----EGRDAFVKSLYDGI------FVRIVRRINETI--- 422

  Fly   397 ETSQRDLKNKHADL-VRTVHELD----KVKDNNN--QLTRENKKLGDDLHEAKGAINELNRRL-- 452
                    ||..|. :.::..||    :..|||:  ||                .||..|..|
  Fly   423 --------NKQVDQPMNSIGVLDIFGFENFDNNSFEQL----------------CINYANENLQQ 463

  Fly   453 ----HELELELRRLENERDELTAAYKEAEAGRKAEEQRGQR------LAADFNQYRHDAERRLAE 507
                |..::|....:||  .:...:.|.:..::..:..|.:      |..:.:::....::.|.|
  Fly   464 FFVGHIFKMEQDEYQNE--HINWQHIEFQDNQQILDLIGMKPMNLMSLIDEESKFPKGTDQTLLE 526

  Fly   508 K--------DEEIEAIRKQTSI-------EIEQLNARVIEAETR------LKTEVTRIKKKLQIQ 551
            |        ...::....|||:       .:...|......:.|      |:|.|.|...|..:.
  Fly   527 KLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQRSTNKYLVD 591

  Fly   552 ITELEMSLDVANK---------TNIDLQKVIKKQSLQLTELQAH-----------YEDVQRQLQA 596
            |...||.:|.|.|         .::|:        |..|..|||           |::.:
  Fly   592 IFPHEMPMDTAKKQPTLCVKFRNSLDM--------LMRTLSQAHPYFIRCIKPNEYKEPK----- 643

  Fly   597 TLD-QYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKL 660
            ..| :..|.|.|.:|:. |...:|........|.|....:|......:..|...:.      .||
  Fly   644 NFDKELCVRQLRYSGMM-ETARIRRAGYPIRHAYRAFVERYRLLVPPVGPLEQCDC------RKL 701

  Fly   661 EQELSVVA----SDYEEVSKELRISDE-----RYQKVQVELKHVVEQVHEEQERIVKLETIKKSL 716
            .:::..||    ||.:....:|.:.||     ..|:.|:.||.:| .:.....|::....:|:..
  Fly   702 ARQICEVALPADSDRQYGKTKLFLRDEDDASLELQRSQLMLKSIV-TIQRGIRRVLFRRYMKRYR 765

  Fly   717 EVEVK-------NLSIRLEEV------ELNAVAGSKRIISKLE-ARIRDLELE------------ 755
            |..:.       .|..|..:|      .|.|...::::.:|.. .|.|.::|:
  Fly   766 EAIITVQRYWRGRLQRRKYQVMRQGFHRLGACIAAQQLTTKFTMVRCRTIKLQALSRGYLVRKDF 830

  Fly   756 ----LEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQE 816
                ||..|:...       |||..:|  |.:.:|.:: |:.||               ||.||:
  Fly   831 QKKLLERRKQNQL-------KKEELLK--LAKMKEAEE-LLRLQ---------------QLKEQK 870

  Fly   817 GVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRT 856
             ..:|...:.:|.|.|.....:.|.....::..::.|.||
  Fly   871 -EREQREQQEKRLQEEQRLKAEAAARNALAMAAVQQKRRT 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	175/1005 (17%)
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	133/789 (17%)
		IQ	765..785	CDD:197470	3/19 (16%)
		Atrophin-1	<820..>946	CDD:460830	24/116 (21%)
		MyTH4	1031..1239	CDD:470587
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020