Protein Alignment Prm and didum

DIOPT Version :9

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_724569.1
• Gene: didum / 35680
• FlyBaseID: FBgn0261397
• Length: 1800
• Species: Drosophila melanogaster
• Alignment Length: 877
• Identity: 164/877 - (18%)
• Similarity: 329/877 - (37%)
• Gaps: 263/877 - (29%)

  Fly    25 DVNIEYIQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLS---VQVIQMSERLEEAEGGA 86
            ::.:::|||       |||.|.....:.........:|:.:|:|.   :.::|...|
  Fly   745 NIVMKWIQD-------EDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVR-------- 794

  Fly    87 EHQFEANRKRDAELLKLRKLLEDV------HLESEETT--------LLLKK-------------- 123
              :|...|    :.|:::|::..:      :|..|.|.        |:|.|
  Fly   795 --RFVYRR----QFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRL 853

  Fly   124 KHNEIITDFQEQVE-ILTKNKARAEKD---KAKFQTEVYELLSQIESYNK------------EKI 172
            :|:  |:..|.... :|.:||..|.:|   ..:.|..|...|:: .:|.|            .:.
  Fly   854 RHS--ISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALAR-RAYQKRRRNIIICQAAIRRF 915

  Fly   173 VSEKHISKLEV---SISELNVKIEELNRTVIDISSHRSRLSQENIEL---TKDVQDLKVQLDTVS 231
            ::.:...:::.   :||.:..|...|...:|.:......|:::|..|   |.::..||::|:.
  Fly   916 LARRKFKRMKAEAKTISHMENKYMGLENKIISMQQRIDELNRDNSNLKHKTSEISVLKMKLEL-- 978

  Fly   232 FSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQLVKANAD 296
              |..:.::.::.:...:|:|:   |:|:...|:|.|.|.....|||...|
  Fly   979 --KKTLEAEFKNVKAACQDKDK---LIEALNKQLEAERDEKMQLLEENGHA-------------- 1024

  Fly   297 ATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLE----KMKTRLASEVEVL 357
                |.:|.|:.....:|.||:||:           |:.:|....|.|    ..:.|:.:|
  Fly  1025 ----QEEWISQKQTWRQENEELRRQ-----------IDEIIDMAKNAEVNQRNQEDRMLAE---- 1070

  Fly   358 IIDLEKSNNSCRELTKSVNTLEKHNVELKSRL---------------------DETIILYETSQR 401
             ||..:.|.:.:...|....:|..|..||..|                     :|..:.|.:::.
  Fly  1071 -IDNRELNEAYQRAIKDKEVIENENFMLKEELSRLTAGSFSLHARKASNASSQNEDDVGYASAKN 1134

  Fly   402 DLK-NKHADL----------------VRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELN 449
            .|. |:..||                :|::  |::.|..:..|..:..||     .::....|.:
  Fly  1135 TLDINRPPDLLSKNYSYNDSTSLVVKLRSI--LEEEKQKHKVLQEQYIKL-----SSRHKPTEDS 1192

  Fly   450 RRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEA 514
            .|:.|||:|..:|.:|.|:|..:.|.   |.:..|...|..|.      .:..||..|:..:::|
  Fly  1193 FRVSELEVENEKLRSEYDQLRTSIKH---GVEINELNAQHAAL------QEEVRRRREECIQLKA 1248

  Fly   515 I-----RKQTSIEIEQLNAR------VIEA-------ETRLKTEVTRIKKKLQIQITELEMSLDV 561
            :     :...|:|.|.|..|      ::||       ..:|::|:..|.::...::.|:...::.
  Fly  1249 VLLQQSQSMRSLEPESLQMRGNDVNELMEAFHSQKLINRQLESELKAITEEHNSKLVEMTQEIER 1313

  Fly   562 ANKTNIDLQKVI-----KKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSH 621
            .|....:||||:     :.:...:..|:.:...::|:||..:.|:.:.|..|...|.:|:..|
  Fly  1314 LNNEKDELQKVMFESIDEFEDSNVDTLRQNDRYLRRELQKAVAQFLLVQEELKLANAKLKAYR-- 1376

  Fly   622 LDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVV---ASDYEEVSKEL----- 678
             ....:.:..:|   ||.....:..|:|:|.....|.|.:....::   :||.:::.:.|
  Fly  1377 -QDGGQLEHKIE---EEMIRNKSNGTSADVGANVTKQKSQNPQGLMKFHSSDLDKILQRLLSALT 1437

  Fly   679 --------------------RISD---------ERYQKVQVELKHVVEQVHEEQERIVKL----- 709
                                |.:|         |...|..:::|.:....|..:.|::.|
  Fly  1438 PRTVVGLLPGFPAYLIFMCIRYTDLTNADDDVRELLSKFVIQIKKMHRTPHPIENRVIWLVNSIT 1502

  Fly   710 ------------ETIK----KSLEVEVKNLSI 725
                        |.:|    |..:.::||.::
  Fly  1503 LLNLMKQYGDVDEYVKFNTEKQNQQQLKNFNL 1534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	161/868 (19%)
didum	NP_724569.1	MYSc	65..778	CDD:214580	8/39 (21%)
		MYSc_Myo5	84..767	CDD:276831	7/28 (25%)
		IQ	900..922	CDD:197470	1/21 (5%)
		GBP_C	<971..1086	CDD:303769	33/155 (21%)
		coiled coil	1049..1068	CDD:293879	4/18 (22%)
		coiled coil	1077..1086	CDD:293879	1/8 (13%)
		JAKMIP_CC3	<1190..1299	CDD:292653	29/117 (25%)
		Myo5_CBD	1424..1792	CDD:271254	15/111 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840