Protein Alignment Prm and Myh14

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_001094160.1
• Gene: Myh14 / 308572
• RGDID: 1306821
• Length: 2000
• Species: Rattus norvegicus
• Alignment Length: 875
• Identity: 220/875 - (25%)
• Similarity: 406/875 - (46%)
• Gaps: 48/875 - (5%)

  Fly    15 RATSTGPGTADVNIEYIQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERL 79
            ||...|...|       |.|.||...:..:...|:|||.||..|.:.|:::.||..::..:...|
  Rat  1119 RAEEEGGARA-------QLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEALRGEL 1176

  Fly    80 EEAEGGAEHQFEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKA 144
            |:.......|.|...||:.|:.:|:|.||:.....|.....|:::|::.:.:..||:|...:.|:
  Rat  1177 EDTLDSTNAQQELRSKREQEVTELKKTLEEEARTHEVAMQELRQRHSQALVELTEQLEQARRGKS 1241

  Fly   145 RAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVK-----------IEELNRT 198
            ..||.:...:.||.||.:::.|....:...|:...:||..:.|:..:           .|:|.|.
  Rat  1242 VWEKTRLSLEAEVSELKTELSSLQTSRQEGEQKRRRLESQLQEVQGRSSDSERARAEAAEKLQRA 1306

  Fly   199 VIDISSHRSRLSQ---ENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLES 260
            .:::.|..:.||:   :.|.|:|::              |...|||.|.:..|::|.|.:..|.|
  Rat  1307 QVELESVSTALSEAESKAIRLSKEL--------------SSAESQLHDTQELLQEETRAKLALGS 1357

  Fly   261 SLHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVR 325
            .:..:|.|...:|.|:|||..||....|:|....|..:.|:.: ..|.||..|..||.||:....
  Rat  1358 RVRALEAEAAGLREQMEEEVVARERAGRELQTTQAQLSEWRRR-QEEEAAVLEAGEEARRRAARE 1421

  Fly   326 ITELEEHIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLD 390
            ...|.:.:......|..||:.:.||..|::...:||.:.......|.|.....::...|.|:.:.
  Rat  1422 AETLAQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVL 1486

  Fly   391 ETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHEL 455
            ..:...|..:.:.:.:.|..:.....|::.::...:|.|:|:.|..:|.....:.:::.:.:|||
  Rat  1487 RAVEDRERVEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHEL 1551

  Fly   456 ELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTS 520
            |...|..|....:|.....|.|....|.|....||.......:...||.|..:|:..|..|:|.:
  Rat  1552 ERARRVAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRRQLA 1616

  Fly   521 IEIEQLNARVIEAETRLKTEVTRI--KKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTEL 583
               :||....:|.:...|.....:  :|||::::.||:.....|.:...:..|.:||...|:.||
  Rat  1617 ---KQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSAAGQGKEEAVKQLKKMQAQMKEL 1678

  Fly   584 QAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTT 648
            ....|:.:...:........:::||.||..|:..::..|.:::||:|..:...:|.|..:.....
  Rat  1679 WREVEETRSSREEMFTLSRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVASGNL 1743

  Fly   649 ANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIK 713
            :..:.:..|.:||..|..:..:.||......:..:.|:|:.::::.:..::..|:....|.|:.:
  Rat  1744 SKAATLEEKRQLEGRLGQLEEELEEEQNNSELLKDHYRKLVLQVETLTTELSAERSFSAKAESGR 1808

  Fly   714 KSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVK 778
            :.||.:::.|..||.|.:..|.|..|.:|:.||:::...|.:||:|.|....:.|::|:.|:.:|
  Rat  1809 QQLERQIQELRARLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLK 1873

  Fly   779 EVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTA 843
            ||::|.:|:::....|:|.|:||..::...:|||.|.|..:.:.....||.|||||...:.|::.
  Rat  1874 EVVLQVDEERRVADQLRDQLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESM 1938

  Fly   844 ESSLNIIRAKHR----TFVTTSTVPGSQVY 869
            ...:..:|.:.|    || ||.||  .||:
  Rat  1939 NREVTTLRNRLRRGPLTF-TTRTV--RQVF 1965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	206/834 (25%)
Myh14	NP_001094160.1	MYSc_Myh14_mammals	115..792	CDD:276893
		Myosin_tail_1	869..1949	CDD:460256	211/854 (25%)