Protein Alignment Prm and Myo18b

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_001419354.1
• Gene: Myo18b / 304551
• RGDID: 1594542
• Length: 2551
• Species: Rattus norvegicus
• Alignment Length: 915
• Identity: 199/915 - (21%)
• Similarity: 359/915 - (39%)
• Gaps: 183/915 - (20%)

  Fly    78 RLEEAEGGAEHQFEANRKR-----DAELLKL----------RKLLEDVHLESEETTLLLKKKHNE 127
            ||..| |.|||...|..:|     |..|||.          ||.:|:: |:    ||.|:||
  Rat  1245 RLHRA-GYAEHMGLAQFRRRFQALDPALLKRLDLTSEGLDERKAVEEL-LQ----TLDLEKK--- 1300

  Fly   128 IITDFQEQVEILTKNKARAEKDKAK--------FQTEVYELLSQIESYNKEKI------------ 172
            .:.....||.:.....:|.|:.:.|        ||......||: :.|.|.||
  Rat  1301 AVAVGHSQVFLKAGVVSRLERQREKLVSRNIVLFQAACRGFLSR-QEYKKLKIRRLAALCIQKNL 1364

  Fly   173 ---------------VSEKHISKLEVSISELNVKIEE---LNRTVIDISSHRSRLSQENIELTKD 219
                           .|.:.:....:|..:|..|.||   |.:.:.:..:.||.|.|....|...
  Rat  1365 TVFLKVKDWPWWGLLASLRPLLSSTLSTEQLRAKEEELTLLRQKLQNSENSRSELRQSADLLESK 1429

  Fly   220 VQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARI 284
            :.||..:|....|........||..|.......|....|::...||:..|..|:.|| ||::.||
  Rat  1430 IADLTSELADERFKGDVACQALESERAERLQALREVQELKAKYQQVQDALGGVQKQL-EEAQQRI 1493

  Fly   285 DLERQLVKANADATSWQNKW------NSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNL 343
            .......|....|..||.:.      |..:..|.::.||.........||||:.:..|.......
  Rat  1494 QTANLEEKPTGGADEWQMRLDCAQLENDFLRKRLQQCEERLDSEMKARTELEQKLGELQSAYEEA 1558

  Fly   344 EKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKH----NVELKSRLDETIILYETSQRDLK 404
            :|...:|..:...|..|||.:...........:.|||.    :::|...|.|:  ::|.|.|:..
  Rat  1559 KKTAHQLRRKCHHLTWDLEDTRVLLENQQSRNHDLEKRQKKFDLQLAQALGES--MFEKSLREKV 1621

  Fly   405 NKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINEL-------NRRLHEL-----EL 457
            ::....||  .||.:::....|..:|..||.:::...:|...||       |:.:..|     ||
  Rat  1622 SRENSGVR--WELGQLQQQLEQKEQEASKLKEEVERLQGQKRELLNCASVGNQGVASLKERVWEL 1684

  Fly   458 ELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIR------ 516
            |...||.|:     ...:.|...|..||..||...:..:.:...::...:::||:|.:|
  Rat  1685 ESNALEQEK-----VRSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKR 1744

  Fly   517 -KQTSIEIE-------------------------QLNARVIEAETRLKTEVTR---IKKKLQIQI 552
             :|..:::|                         |:..|..:.|.||:.::.|   :...:|:.:
  Rat  1745 LRQLEMQLEQEYEEKQAALHEKHDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLL 1809

  Fly   553 TELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEE 617
            ..:|.|     ||:|..:::.|..| ||.:.:|..||..:..:.              |..:||.
  Rat  1810 ATIEDS-----KTSISKEELEKVHS-QLEQSEAKCEDALKTQKV--------------LTADLES 1854

  Fly   618 VRSHLDSANRAKRTVE-----LQYEEA--ASRINE-------LTTANVSLVSIKSKLEQELSVVA 668
            :.|.|::..|:|..|:     ||:|.|  ..||:|       |...:..|::..:....::..:.
  Rat  1855 MHSELENVTRSKSLVDEQLYRLQFERADLLKRIDEDQDDLNGLMQKHKDLIAQSAADIGQIQELQ 1919

  Fly   669 SDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELN 733
            ...||..||.:...|:.|..|:.::: :||...|:..:.:.|.|...||.:.:...::::..|:
  Rat  1920 LQLEEAKKEKQKLWEQLQVAQLRIQY-LEQSTVERAIVSRQEAIICDLESKTEFQKVQMKRFEV- 1982

  Fly   734 AVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDAL 798
                       |..|:||..:::.||..|..:.....|:..:..::.|.:.:.:.:.|:..::..
  Rat  1983 -----------LVIRLRDSMIKMGEELSRAVKAEAQQRENSQYYQQRLEELKAEMQELVQREEEA 2036

  Fly   799 DKSTAKINIYRRQLSE-QEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRTFVTTST 862
            .:...::..|..:|:. ::.:.....|.:||. .:|:||.:...:::|....:    :|.|..|:
  Rat  2037 SRRCMEMEKYVEELAAVRQTLQTDLETSIRRI-ADLQAALEEVASSDSDTESV----QTAVDCSS 2096

  Fly   863 VPGSQ 867
            ..|.:
  Rat  2097 RSGKE 2101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	195/899 (22%)
Myo18b	NP_001419354.1	PTZ00449	<223..561	CDD:185628
		COG5022	547..2077	CDD:227355	194/885 (22%)
		MYSc_Myo18	577..1312	CDD:276837	24/75 (32%)