Protein Alignment Prm and unc-54

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_493596.1
• Gene: unc-54 / 259839
• WormBaseID: WBGene00006789
• Length: 1963
• Species: Caenorhabditis elegans
• Alignment Length: 847
• Identity: 291/847 - (34%)
• Similarity: 491/847 - (57%)
• Gaps: 20/847 - (2%)

  Fly    38 SRLED-----------------KIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGG 85
            |||||                 :|..|:::||.||:.|.:.:|.|:||..::.::.|:|:|..|.
 Worm  1101 SRLEDEQALVSKLQRQIKDGQSRISELEEELENERQSRSKADRAKSDLQRELEELGEKLDEQGGA 1165

  Fly    86 AEHQFEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDK 150
            ...|.|.|:||:|||.|||:.||:.::..|.....|:|||.:.:.:..:|::.|.|.||:.||||
 Worm  1166 TAAQVEVNKKREAELAKLRRDLEEANMNHENQLGGLRKKHTDAVAELTDQLDQLNKAKAKVEKDK 1230

  Fly   151 AKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIE 215
            |:...:..:|.:|::.....|:.:||...:.|:.::||..|.:|.:|.:.|.:|.:.||..||.:
 Worm  1231 AQAVRDAEDLAAQLDQETSGKLNNEKLAKQFELQLTELQSKADEQSRQLQDFTSLKGRLHSENGD 1295

  Fly   216 LTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEES 280
            |.:.::|.:.|::.::..|||:.||||:|||..::|.|.|..:.:.....:.|.:.::..||||.
 Worm  1296 LVRQLEDAESQVNQLTRLKSQLTSQLEEARRTADEEARERQTVAAQAKNYQHEAEQLQESLEEEI 1360

  Fly   281 EARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEK 345
            |.:.::.|||.|||||...|:.::..|...:|:|:|:.:|:...:|.||:|.:::...|..:|||
 Worm  1361 EGKNEILRQLSKANADIQQWKARFEGEGLLKADELEDAKRRQAQKINELQEALDAANSKNASLEK 1425

  Fly   346 MKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADL 410
            .|:||..:::...:|:|::|.....|.|.....:|...|.:.:.|:.....:.:||||:|...||
 Worm  1426 TKSRLVGDLDDAQVDVERANGVASALEKKQKGFDKIIDEWRKKTDDLAAELDGAQRDLRNTSTDL 1490

  Fly   411 VRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKE 475
            .:..:..:::.:....|.||||.|..::.:....:.|..|.:||::..:||||.|::||..|..|
 Worm  1491 FKAKNAQEELAEVVEGLRRENKSLSQEIKDLTDQLGEGGRSVHEMQKIIRRLEIEKEELQHALDE 1555

  Fly   476 AEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTE 540
            |||..:|||.:..|...:.:|.|.:.|:|:.||:||.|..||..:..:|.:.|. :|.|.:.|.|
 Worm  1556 AEAALEAEESKVLRAQVEVSQIRSEIEKRIQEKEEEFENTRKNHARALESMQAS-LETEAKGKAE 1619

  Fly   541 VTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQ 605
            :.||||||:..|.|||::||.|||.|.|.||.:|:...|:.|||...|:.||....|.:|:..|:
 Worm  1620 LLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQVEEEQRNGADTREQFFNAE 1684

  Fly   606 RRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASD 670
            :|...|..|.||:....::|.||::..|.:..:|..:.||......||.|.|.|||.|:..:.:|
 Worm  1685 KRATLLQSEKEELLVANEAAERARKQAEYEAADARDQANEANAQVSSLTSAKRKLEGEIQAIHAD 1749

  Fly   671 YEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAV 735
            .:|...|.:.::||.:|...:...:.|::.:|||....::.::|.||.::|.:.:||:|.|..|:
 Worm  1750 LDETLNEYKAAEERSKKAIADATRLAEELRQEQEHSQHVDRLRKGLEQQLKEIQVRLDEAEAAAL 1814

  Fly   736 AGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDK 800
            .|.|::|:|||.|:|:||.||:.|:||..:..|.|.:.:|.|:|:..|.:||:||...|||.:||
 Worm  1815 KGGKKVIAKLEQRVRELESELDGEQRRFQDANKNLGRADRRVRELQFQVDEDKKNFERLQDLIDK 1879

  Fly   801 STAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRTFVTTSTVPG 865
            ...|:...::|:.|.|.::.....:.::...:||.||:|||.||:||:.:|:|.|  .:.|..||
 Worm  1880 LQQKLKTQKKQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLSKMRSKSR--ASASVAPG 1942

  Fly   866 SQ 867
            .|
 Worm  1943 LQ 1944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	285/831 (34%)
unc-54	NP_493596.1	Myosin_N	28..72	CDD:460670
		MYSc_class_II	95..775	CDD:276951
		Myosin_tail_1	853..1932	CDD:460256	285/831 (34%)