Protein Alignment Prm and Myh8

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_001093955.1
• Gene: Myh8 / 252942
• RGDID: 620356
• Length: 1937
• Species: Rattus norvegicus
• Alignment Length: 825
• Identity: 294/825 - (35%)
• Similarity: 491/825 - (59%)
• Gaps: 1/825 - (0%)

  Fly    31 IQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRK 95
            ||....:..|:.:|..|::::|.||..|.:.|::::|||.::.::|||||||.|....|.|.|:|
  Rat  1105 IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKK 1169

  Fly    96 RDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYEL 160
            |:.|..|||:.||:..|:.|.|:..|:|||.:.:.:..||::.|.:.|.:.||:|::.:.|:.:|
  Rat  1170 RETEFQKLRRDLEEATLQHEATSAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMEIDDL 1234

  Fly   161 LSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKV 225
            .|..|:..|.|...||....||..:|||..|.||..|.:.::::.|:||..|..|.::.:.:...
  Rat  1235 SSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDA 1299

  Fly   226 QLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQL 290
            .:..:|.||.....|:|:.:|:||:|.:.::.|..:|.....:.|.:|.|.|||.|.:.:|:|.|
  Rat  1300 LVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 1364

  Fly   291 VKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVE 355
            .|||::...|:.|:.::...|.||:||.::|...|:...|||:|::..|..:|||.|.||.:|||
  Rat  1365 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVE 1429

  Fly   356 VLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKV 420
            .|::|:|::|.:|..|.|.....:|...|.:.:.:||....|:.|::.:....:|.:..:..::.
  Rat  1430 DLMLDVERTNAACAALDKKQRNFDKVLSEWRQKYEETQAELESCQKESRTLSTELFKVKNAYEES 1494

  Fly   421 KDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQ 485
            .|....|.||||.|..::.:....|.|..:.:||||...:::|.|:.|:.||.:||||..:.||.
  Rat  1495 LDQLETLRRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEG 1559

  Fly   486 RGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQI 550
            :..|:..:.||.:.:.:|::|||||||:.: |:..|.:.:.....::||.|.:.:..|:|||::.
  Rat  1560 KILRIQLELNQVKSEIDRKIAEKDEEIDQL-KRNHIRVVETMQSTLDAEIRSRNDALRVKKKMEG 1623

  Fly   551 QITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGEL 615
            .:.|:|:.|:.||:...:..:..:.....|.:.|.|.:|..|..:...:|.|:.:||...|..|:
  Rat  1624 DLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688

  Fly   616 EEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRI 680
            ||:|:.|:...|:::..|.:..:|:.|:..|.|.|.||::.|.|||.::|.:.|:.|||.:|.|.
  Rat  1689 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRN 1753

  Fly   681 SDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKL 745
            ::|:.:|...:...:.|::.:||:....||.:||:||..||:|..||:|.|..|:.|.|:.|.||
  Rat  1754 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818

  Fly   746 EARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRR 810
            |||:|:||.|:|.|::|:||.:|.|||.||.|||:..|.|||:||::.|||.:||..||:..|:|
  Rat  1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKR 1883

  Fly   811 QLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHR 855
            |..|.|..|.....:.|:.|.|||.||:|||.|||.:|.:|.|.|
  Rat  1884 QAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	290/818 (35%)
Myh8	NP_001093955.1	Myosin_N	35..79	CDD:460670
		Motor_domain	102..769	CDD:473979
		Myosin_tail_1	849..1926	CDD:460256	292/821 (36%)