Protein Alignment Prm and myo-2

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_510092.2
• Gene: myo-2 / 181404
• WormBaseID: WBGene00003514
• Length: 1947
• Species: Caenorhabditis elegans
• Alignment Length: 815
• Identity: 267/815 - (32%)
• Similarity: 454/815 - (55%)
• Gaps: 1/815 - (0%)

  Fly    41 EDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRKRDAELLKLRK 105
            |.:::.|.|.|..|::.|||.:|.:||...:..:::|:||:.......|.|..:|:||||.|||:
 Worm  1128 EARVKDLHDQLADEKDARQRADRSRADQQAEYDELTEQLEDQARATAAQIELGKKKDAELTKLRR 1192

  Fly   106 LLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYELLSQIESYNKE 170
            .||:..|:..|...:||||.::.|.:..:|:|.|.|.|.|.||:|...|.|..|..:.::...|.
 Worm  1193 DLEESGLKFGEQLTVLKKKGSDAIQELSDQIEQLQKQKGRIEKEKGHMQREFDESSAALDQEAKL 1257

  Fly   171 KIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKS 235
            :...|:.....||.:.||.:|.:|.:|.:.|..|.:.||:.||.:|.:.|::|:.::...:..|.
 Worm  1258 RADQERIAKGYEVRLLELRLKADEQSRQLQDFVSSKGRLNSENSDLARQVEELEAKIQAANRLKL 1322

  Fly   236 QVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSW 300
            |..::|:.|:|:.|:|.|.|..|.:....:..||:.::..:|:|...:.:..|||.||:.:...|
 Worm  1323 QFSNELDHAKRQAEEESRERQNLSNLSKNLARELEQLKESIEDEVAGKNEASRQLSKASVELDQW 1387

  Fly   301 QNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSN 365
            :.|:.:|....|:|.:|::::...:.:|:::.:::...|:..||..::||.:|.:...::.|...
 Worm  1388 RTKFETEGLIGADEFDEVKKRQNQKTSEIQDALDACNAKIVALENARSRLTAEADANRLEAEHHA 1452

  Fly   366 NSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRE 430
            .:...|.|.....:|...|.|.::|:..:..:.:|||.:....:..:...:.|.:.|....|.||
 Worm  1453 QAVSSLEKKQKAFDKVIDEWKKKVDDLYLELDGAQRDARQLSGEAHKLRGQHDTLADQVEGLRRE 1517

  Fly   431 NKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFN 495
            ||.|.|:..:...:::|..|..|.|...|||||.|::||.....||||..::||.:..|...:.:
 Worm  1518 NKSLSDETRDLTESLSEGGRATHALSKNLRRLEMEKEELQRGLDEAEAALESEESKALRCQIEVS 1582

  Fly   496 QYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITELEMSLD 560
            |.|.:.|:|:|||:||.|..||.....|:.:.| .:::||:.|:|:.|:||||:..|.|||::||
 Worm  1583 QIRAEIEKRIAEKEEEFENHRKVHQQTIDSIQA-TLDSETKAKSELFRVKKKLEADINELEIALD 1646

  Fly   561 VANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSHLDSA 625
            .|||.|.|.||.|::...|:.|||...::.|::.:...:....|:|:||....|.||:...|::.
 Worm  1647 HANKANEDAQKNIRRYLDQIRELQQTVDEEQKRREEFREHLLAAERKLAVAKQEQEELIVKLEAL 1711

  Fly   626 NRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQV 690
            .||:|.||...:|.....|||.:.||:|.:.||:|:.|::::.||..|...||..|::|.::...
 Worm  1712 ERARRVVESSVKEHQEHNNELNSQNVALAAAKSQLDNEIALLNSDIAEAHTELSASEDRGRRAAS 1776

  Fly   691 ELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELE 755
            :...:.|.:..|||:..:||..||.||..||:|..|.:..|...:.|..:.|.|.|.|::..:.:
 Worm  1777 DAAKLAEDLRHEQEQSQQLERFKKQLESAVKDLQERADAAEAAVMKGGAKAIQKAEQRLKAFQSD 1841

  Fly   756 LEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGVSQ 820
            ||.|.||..|..|.|.:.:|.|:|...|..||:||...||:.::|.|||:.:.::||.|.|..:.
 Worm  1842 LETESRRAGEASKTLARADRKVREFEFQVAEDKKNYDKLQELVEKLTAKLKLQKKQLEEAEEQAN 1906

  Fly   821 QTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHR 855
            ...::.|..|..||.||:|||:||..|..||::.|
 Worm  1907 SHLSKYRTVQLSLETAEERADSAEQCLVRIRSRTR 1941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	266/811 (33%)
myo-2	NP_510092.2	COG5022	27..1478	CDD:227355	101/349 (29%)
		MYSc_class_II	95..782	CDD:276951
		SMC_prok_B	1097..1936	CDD:274008	264/808 (33%)