Protein Alignment Prm and myo-3

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_506065.2
• Gene: myo-3 / 179676
• WormBaseID: WBGene00003515
• Length: 1969
• Species: Caenorhabditis elegans
• Alignment Length: 853
• Identity: 285/853 - (33%)
• Similarity: 486/853 - (56%)
• Gaps: 22/853 - (2%)

  Fly    27 NIEYIQDLSSLSRLEDKIR-------LLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEG 84
            |.:..::.|.:::|:..|:       .|:::||.||..||:.:|.:::...::.:::||||:..|
 Worm  1104 NAKLAENNSIIAKLQRLIKELTARNAELEEELEAERNSRQKSDRSRSEAERELEELTERLEQQGG 1168

  Fly    85 GAEHQFEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKD 149
            ....|.|||:||:||:.|||:..|:..|..|.....|:|:|.:.:.:..||:|.|.|.||::|.:
 Worm  1169 ATAAQLEANKKREAEIAKLRREKEEDSLNHETAISSLRKRHGDSVAELTEQLETLQKLKAKSEAE 1233

  Fly   150 KAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENI 214
            |:|.|.::.|.....:|..:.:...||.:..:||..|||..|.:|.:|.:.|.::.::||:.||.
 Worm  1234 KSKLQRDLEESQHATDSEVRSRQDLEKALKTIEVQYSELQTKADEQSRQLQDFAALKNRLNNENS 1298

  Fly   215 ELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEE 279
            :|.:.::::..||:::...||.:.|||::.||..::|.|.|..|.::...:|.|...:|..|:||
 Worm  1299 DLNRSLEEMDNQLNSLHRLKSTLQSQLDETRRNYDEESRERQALAATAKNLEHENTILREHLDEE 1363

  Fly   280 SEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLE 344
            :|::.||.||:.|.||:...|:.:::||...:.||:|..::..|:::.||.:..|.|..|:.:.|
 Worm  1364 AESKADLTRQISKLNAEIQQWKARFDSEGLNKLEEIEAAKKALQLKVQELTDTNEGLFAKIASQE 1428

  Fly   345 KMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHN-------VELKSRLDETIILYETSQRD 402
            |::.:|..:::....|:||:       ...|...|||.       .|.|.:.|:.....:.:|||
 Worm  1429 KVRFKLMQDLDDAQSDVEKA-------AAQVAFYEKHRRQFESIIAEWKKKTDDLSSELDAAQRD 1486

  Fly   403 LKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERD 467
            .:....||.:.....|::.:..:...||||.|..::.:....:.|..|.:.||:..:|:||.|::
 Worm  1487 NRQLSTDLFKAKTANDELAEYLDSTRRENKSLAQEVKDLTDQLGEGGRSVAELQKIVRKLEVEKE 1551

  Fly   468 ELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIE 532
            ||..|..||||..:|||.:..|...:.:|.|.:.|:|:.||:||.|..|:.....:|.:.| .:|
 Worm  1552 ELQKALDEAEAALEAEEAKVLRAQIEVSQIRSEIEKRIQEKEEEFENTRRNHQRALESMQA-TLE 1615

  Fly   533 AETRLKTEVTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQAT 597
            |||:.|.|..||||||:..|.:||::||.||:...|.||.|||....:.|||...|:.|||....
 Worm  1616 AETKQKEEALRIKKKLESDINDLEIALDHANRAYADAQKTIKKYMETVQELQFQIEEEQRQKDEI 1680

  Fly   598 LDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQ 662
            .:|:..:::|.|.|..|.:|:....::|.||:|..|.:..|...:.|:|.....:|...:.|||.
 Worm  1681 REQFLASEKRNAILQSEKDELAQQAEAAERARRNAEAECIELREQNNDLNAHVSALTGQRRKLEG 1745

  Fly   663 ELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRL 727
            ||....::.||::.||:.:.|:.||...:...:.|::.:|||..:.:|.|:|.||:::|.:.|||
 Worm  1746 ELLAAHAELEEIANELKNAVEQGQKASADAARLAEELRQEQEHSMHIERIRKGLELQIKEMQIRL 1810

  Fly   728 EEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLI 792
            ::.|..|:.|.|:||::||||||.:|.||:.|:|||.:|.|..||.||.||||..|..|::||..
 Worm  1811 DDAENAALKGGKKIIAQLEARIRAIEQELDGEQRRHQDTEKNWRKAERRVKEVEFQVVEEKKNEE 1875

  Fly   793 LLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRTF 857
            .|.:.:||...|:.|::||:.|.|.|:.....:.:....:.|.||:|||.||::|:.:|.|.|..
 Worm  1876 RLTELVDKLQCKLKIFKRQVEEAEEVAASNLNKYKVLTAQFEQAEERADIAENALSKMRNKIRAS 1940

  Fly   858 VTTSTVPG 865
            .:.:...|
 Worm  1941 ASMAPPDG 1948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	281/832 (34%)
myo-3	NP_506065.2	COG5022	32..1420	CDD:227355	100/315 (32%)
		MYSc_class_II	100..779	CDD:276951
		SMC_prok_B	1182..1933	CDD:274008	258/758 (34%)