Protein Alignment Prm and Myh6

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: XP_006518740.1
• Gene: Myh6 / 17888
• MGIID: 97255
• Length: 1939
• Species: Mus musculus
• Alignment Length: 832
• Identity: 291/832 - (34%)
• Similarity: 498/832 - (59%)
• Gaps: 15/832 - (1%)

  Fly    31 IQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRK 95
            :|....|...:.:|..|:::||.||..|.::|:.::|||.::.::|||||||.|....|.|.|:|
Mouse  1104 LQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKK 1168

  Fly    96 RDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYEL 160
            |:||..|:|:.||:..|:.|.|...|:|||.:.:.:..||::.|.:.|.:.||:|::|:.|:.::
Mouse  1169 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1233

  Fly   161 LSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKV 225
            .|.:|...|.|...||....||...:|..||:||..|::.|.::.|::|..||.||.:.:::.:.
Mouse  1234 TSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA 1298

  Fly   226 QLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQL 290
            .:..::..|.....|:||.:|:||:|.:.::.|..:|.....:.|.:|.|.|||.||:.:|:|.|
Mouse  1299 LISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVL 1363

  Fly   291 VKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVE 355
            .|||::...|:.|:.::...|.||:||.::|...|:.:.||.:|::..|.::|||.|.||.:|:|
Mouse  1364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIE 1428

  Fly   356 VLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKV 420
            .|::|:|:||.:...|.|.....:|...|.|.:.:|:....|:||::.::...:|.:..:..::.
Mouse  1429 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493

  Fly   421 KDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQ 485
            .::.....||||.|.:::.:....:.|..:.:||||...::||.|:.||.:|.:||||..:.||.
Mouse  1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEG 1558

  Fly   486 RGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQI 550
            :..|...:|||.:.:.||:|||||||:|..::.....::.|... ::||||.:.|..|:|||::.
Mouse  1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTS-LDAETRSRNEALRVKKKMEG 1622

  Fly   551 QITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATL-------DQYAVAQRRL 608
            .:.|:|:.|..||:...:.||.:|..       |||.:|.|.||...:       :..|:.:||.
Mouse  1623 DLNEMEIQLSQANRIASEAQKHLKNS-------QAHLKDTQLQLDDAVHANDDLKENIAIVERRN 1680

  Fly   609 AGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEE 673
            ..|..||||:|:.::...|:::..|.:..|.:.|:..|.:.|.||::.|.|:|.:|:.:.::.||
Mouse  1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEE 1745

  Fly   674 VSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGS 738
            ..:|.|.::|:.:|...:...:.|::.:||:....||.:||::|..:|:|..||:|.|..|:.|.
Mouse  1746 AVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG 1810

  Fly   739 KRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTA 803
            |:.:.|||||:|:||.|||.|::|:||::|.:||.||.:||:..|.|||:|||:.|||.:||...
Mouse  1811 KKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQL 1875

  Fly   804 KINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHR 855
            |:..|:||..|.|..:....::.|:.|.||:.||:|||.|||.:|.:|||.|
Mouse  1876 KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	287/825 (35%)
Myh6	XP_006518740.1	Myosin_N	32..76	CDD:460670
		MYSc_class_II	99..768	CDD:276951
		Myosin_tail_1	848..1925	CDD:460256	288/828 (35%)