Protein Alignment Prm and Myh1

DIOPT Version :9

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_109604.1
• Gene: Myh1 / 17879
• MGIID: 1339711
• Length: 1942
• Species: Mus musculus
• Alignment Length: 819
• Identity: 292/819 - (35%)
• Similarity: 492/819 - (60%)
• Gaps: 1/819 - (0%)

  Fly    37 LSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRKRDAELL 101
            :..|:.:|..|::::|.||..|.:.|::::|||.::.::|||||||.|....|.|.|:||:||..
Mouse  1115 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1179

  Fly   102 KLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYELLSQIES 166
            |:|:.||:..|:.|.|...|:|||.:.:.:..||::.|.:.|.:.||:|::.:.|:.:|.|.:|.
Mouse  1180 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMEV 1244

  Fly   167 YNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKVQLDTVS 231
            .:|.|...||....||..:|||..|.||..|.:.::::.|.||..|:.|.::.:.:....:..:|
Mouse  1245 ISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEKDSLVSQLS 1309

  Fly   232 FSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQLVKANAD 296
            ..|.....|:|:.:|:||:|.:.:|.|..:|.....:.|.:|.|.|||.||:.:|:|.:.|||::
Mouse  1310 RGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSE 1374

  Fly   297 ATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVEVLIIDL 361
            ...|:.|:.::...|.||:||.::|...|:.:.|||:|::..|..:|||.|.||.:|||.|:||:
Mouse  1375 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDV 1439

  Fly   362 EKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQ 426
            |::|.:|..|.|.....:|...|.|.:.:||....|.||::.::...:|.:..:..::..|:...
Mouse  1440 ERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKESRSLSTELFKIKNAYEESLDHLET 1504

  Fly   427 LTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLA 491
            |.||||.|..::.:....|.|..:|:||||...:::|.|:.||.||.:||||..:.||.:..|:.
Mouse  1505 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQ 1569

  Fly   492 ADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITELE 556
            .:.||.:.:.:|::|||||||:.: |:..|.:.:.....::||.|.:.:..|:|||::..:.|:|
Mouse  1570 LELNQVKSEIDRKIAEKDEEIDQL-KRNHIRVVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1633

  Fly   557 MSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSH 621
            :.|:.:|:...:..:..:.....|.:.|.|.:|..|..:...:|.|:.:||...|..|:||:|:.
Mouse  1634 IQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRAT 1698

  Fly   622 LDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQ 686
            |:...|:::..|.:..:|:.|:..|.|.|.||::.|.|||.::|.:..:.|::.:|.|.::|:.:
Mouse  1699 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAK 1763

  Fly   687 KVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRD 751
            |...:...:.|::.:||:....||.:||:||..||:|..||:|.|..|:.|.|:.|.|||||:|:
Mouse  1764 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRE 1828

  Fly   752 LELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQE 816
            ||.|:|.|::|:.|.||.|||.||.|||:..|.|||:||::.|||.:||..:|:..|:||..|.|
Mouse  1829 LEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKVKAYKRQAEEAE 1893

  Fly   817 GVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHR 855
            ..|.....:.|:.|.|||.||:|||.|||.:|.:|.|.|
Mouse  1894 EQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSR 1932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	290/815 (36%)
Myh1	NP_109604.1	Myosin_N	35..73	CDD:367160
		MYSc_Myh1_mammals	100..773	CDD:276875
		Actin-binding. /evidence=ECO:0000250	662..684
		Actin-binding. /evidence=ECO:0000250	764..778
		Myosin_tail_1	853..1930	CDD:366712	290/815 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1156..1175		10/18 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810