Protein Alignment Prm and unc-15

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_001379131.1
• Gene: unc-15 / 172491
• WormBaseID: WBGene00006754
• Length: 872
• Species: Caenorhabditis elegans
• Alignment Length: 867
• Identity: 430/867 - (49%)
• Similarity: 592/867 - (68%)
• Gaps: 9/867 - (1%)

  Fly    14 YRATST----GPGTADVNIEY----IQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSV 70
            ||:.|.    .|..|.....:    :.||.||:||||||||||:|||.|||||.|:|||:|||||
 Worm     4 YRSPSAALLKSPSQAAFGAPFGSMSVADLGSLTRLEDKIRLLQEDLESERELRNRVERERADLSV 68

  Fly    71 QVIQMSERLEEAEGGAEHQFEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQ 135
            |||.:::|||:|||..:.|.|:||||:.||.|||||||:..||||:...:|:|||.:...|:|:|
 Worm    69 QVIALTDRLEDAEGTTDSQIESNRKREGELSKLRKLLEESQLESEDAMNVLRKKHQDSCLDYQDQ 133

  Fly   136 VEILTKNKARAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVI 200
            :|.|.|..|:.::::.:.|.||.||.:.|:...|:|..:||...:.|...:||..|:|:||:.|.
 Worm   134 IEQLQKKNAKIDRERQRVQHEVIELTATIDQLQKDKHTAEKAAERFEAQANELANKVEDLNKHVN 198

  Fly   201 DISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQV 265
            |::..|.||..||.:|.|:|.|.|||||.:...|..:..|||:|||||||.:|.||.|:|.||||
 Worm   199 DLAQQRQRLQAENNDLLKEVHDQKVQLDNLQHVKYTLAQQLEEARRRLEDAERERSQLQSQLHQV 263

  Fly   266 EIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELE 330
            ::||||||..|:|||.||.|.|.:|..||.:.|.|::|:::|||...||||::|:|...:..|.|
 Worm   264 QLELDSVRTALDEESIARSDAEHKLNLANTEITQWKSKFDAEVALHHEEVEDLRKKMLQKQAEYE 328

  Fly   331 EHIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIIL 395
            |.||.::.|::.|||.|:||.|||||||:||||:.|:...|.::...||:...|||.|:||..:.
 Worm   329 EQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNTIALLERAREQLERQVGELKVRIDEITVE 393

  Fly   396 YETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELR 460
            .|.:||:|:..:|:|.:..|..:|..:....|.||||||.|:|||||.|:.:.||:||||:||..
 Worm   394 LEAAQRELRAVNAELQKMKHLYEKAVEQKEALARENKKLHDELHEAKEALADANRKLHELDLENA 458

  Fly   461 RLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQ 525
            ||..|..||..|.|||:|.|:..|.|.||..|:....|.:.||||.||:||:||:||....||::
 Worm   459 RLAGEIRELQTALKEADAQRRDAENRAQRALAELQALRIEMERRLQEKEEEMEALRKNLQFEIDR 523

  Fly   526 LNARVIEAETRLKTEVTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDV 590
            |.|.:.:||.|:|:|::|:|||.|.:|.||||::|..|:.||:.||.|||||.||..|||..||.
 Worm   524 LIAALADAEARMKSEISRLKKKYQAEIAELEMTVDNLNRANIEAQKTIKKQSEQLKILQASLEDT 588

  Fly   591 QRQLQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVS 655
            |||||..|||||:|||::|.|:.||||.::.||:|.||::..|:..|||..||::|.:.|.:|.|
 Worm   589 QRQLQQVLDQYALAQRKVAALSAELEECKTALDNAIRARKQAEVDLEEANGRISDLISINNNLTS 653

  Fly   656 IKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEV 720
            ||:|||.|||...:|.:||:|||..:|||..:...:....|||:|||||..:|::.::||||.:|
 Worm   654 IKNKLETELSTAQADLDEVTKELHAADERANRALADAARAVEQLHEEQEHSMKIDALRKSLEEQV 718

  Fly   721 KNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCE 785
            |.|.::::|.|..|:.|.||:|:|||.||||||..|:||.|||.||...||||:|.:|||....:
 Worm   719 KQLQVQIQEAEAAALLGGKRVIAKLETRIRDLETALDEETRRHKETQNALRKKDRRIKEVQQLVD 783

  Fly   786 EDQKNLILLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNII 850
            |:.||.::.||..|:.|.|:||.:|||:|.|.|:.|...||||:|.|||.||.|||.|||||::|
 Worm   784 EEHKNFVMAQDTADRLTEKLNIQKRQLAESESVTMQNLQRVRRYQHELEDAEGRADQAESSLHLI 848

  Fly   851 RAKHRTFVTTSTVPGSQVYIQE 872
            |||||:.|.|.. ..|::::.|
 Worm   849 RAKHRSSVVTGK-SSSKIFVTE 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	416/818 (51%)
unc-15	NP_001379131.1	Myosin_tail_1	<32..839	CDD:460256	407/806 (50%)