Protein Alignment Prm and Mhcl

DIOPT Version :10

• Sequence 1: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: XP_061515843.1
• Gene: Mhcl / 1270789
• VectorBaseID: AGAMI1_011631
• Length: 2419
• Species: Anopheles gambiae
• Alignment Length: 881
• Identity: 195/881 - (22%)
• Similarity: 368/881 - (41%)
• Gaps: 176/881 - (19%)

  Fly    37 LSRLEDKIRLLQDDLEVEREL-----------RQRIEREK-ADLSVQVIQMSER--LEEAEGG-- 85
            |..||.|    :|||..:|.:           |:|:.|.: .:|:|:.||.:.|  |:..:..
Mosquito  1356 LGALEAK----RDDLLSDRVIQLQAHCRGYLARRRLARRRLQELAVKCIQRNVRAFLKVRDWPWW 1416

  Fly    86 ----------AEHQFEANRK-RDAELLKLRKLLEDVHLESEE---TTLLLKKKHNEIITDFQEQ- 135
                      |.|:.|...| ...||.::|..||.:..|..|   |...|:.:.::|.::..|:
Mosquito  1417 RLLVRVTPLLAVHRTEEQLKAATVELQQVRAKLEKIESERNELKATNHKLEARLSDITSELTEEH 1481

  Fly   136 --VEILTKNKARAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRT 198
              ..::|:..|....::.:.:.||.|..|:   |...:..|||...:|..:.||||...::.
Mosquito  1482 SSSNLITERLAAETSERLRLEKEVKEYESK---YRHLQESSEKMEMELLCAKSELNCDFDDC--- 1540

  Fly   199 VIDISSHRSRLSQENIELTKDVQDLK---VQLDTVSFSKS------QVISQLEDARRRLEDEDRR 254
                    |.|.:  .:.|.|..||.   |..|....:||      :|..:||..::||:.:..
Mosquito  1541 --------STLGE--YDSTGDGADLPLGGVPADGAELAKSYRLRYERVARELEFTKKRLQTQHE- 1594

  Fly   255 RSLLESSLHQVEIELDSVRNQLEE---ESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVE 316
                    |.:| :|..::.|||:   ::...::.:||:|.          :|..:......|:.
Mosquito  1595 --------HDLE-QLVGLKKQLEKKLADAYEEVEEQRQVVA----------QWKRKAQKMTNEMN 1640

  Fly   317 EIRRKY----------QVRITELEEHIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCREL 371
            ::|..|          :.|..:.:...::|........:.|.|:|.|.:||:.:..|...:..::
Mosquito  1641 DLRMLYEEQNSRNNLLEKRQRKFDAECQTLQDSARQERQAKERMAREKDVLMAEKCKLEQTVSDI 1705

  Fly   372 TKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRENKKLGD 436
            ...:...|:....|:..|||......|.:               |:.::|...|:|.|..|:..:
Mosquito  1706 RLELELKEEKVTALQQELDEMAFGGGTEE---------------EIAQLKRQKNELDRRCKEQDE 1755

  Fly   437 DLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDA 501
            :|.|..|.|..|.:....||:.   ||..|.|   |.|||:
Mosquito  1756 ELDEMAGQIQLLEQAKLRLEMS---LETSRKE---ARKEAQ------------------------ 1790

  Fly   502 ERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITELEMSLDVANKTN 566
                 ::|:|:|.||..:..:|:.|..: :|.|...:|::.|.|.:|:.::..|| ..|.|
Mosquito  1791 -----QRDDEMEEIRGASYKKIKSLECQ-LEQEHEERTQLLRDKHELERKLASLE-DQDRA---- 1844

  Fly   567 IDLQKVIKKQSLQLTELQAH-YEDVQRQLQATLDQY---AVAQRRLAGLNGELEEVRSHLDSANR 627
               ::..::..:|..:..|. |..:.|..|:.||:.   :.::..:..|..:||:..|...:|.:
Mosquito  1845 ---ERAAEEAMVQRLKRDARKYRALLRDAQSQLDRAKGDSASKALVRQLRNQLEDAESARVAALK 1906

  Fly   628 AKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVEL 692
            |::.:|.:.::|.....|...|       :::.|...:|...|..|:..::..::|...::..:.
Mosquito  1907 ARQVLEGELQDAQLLFEETQRA-------RNEAEDRATVAQRDRAELQAQIDENEEEMAELMKKY 1964

  Fly   693 KHVVEQVHEEQE-------RIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIR 750
            ...|:|:..||.       |:.:||..||||:.:|..|:.|||.||......:.....:||.|.:
Mosquito  1965 SATVKQLSSEQSLIAEYELRVSELEGEKKSLKEQVVELATRLESVETIGEPSNSMAFKRLELRTK 2029

  Fly   751 DLE--LELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLS 813
            :||  ||.|:..|...| |::.|.|: :::::..:..:.:......||||.|....:...|.:||
Mosquito  2030 ELESRLEFEQATRARIE-IQLARHKD-SLEKLQGELSQARNREAQAQDALKKGQKMVRELRDELS 2092

  Fly   814 EQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNI 849
            ......|:...:.:..::.:|.||....:|.:.|.:
Mosquito  2093 TLANRDQEGLLKRKELEKRIETAESETASARADLRL 2128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	195/881 (22%)
Mhcl	XP_061515843.1	None