DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prm and LOC100495690

DIOPT Version :9

Sequence 1:	NP_523982.2	Gene:	Prm / 39002	FlyBaseID:	FBgn0003149	Length:	879	Species:	Drosophila melanogaster
Sequence 2:	XP_031750519.1	Gene:	LOC100495690 / 100495690	-ID:	-	Length:	1137	Species:	Xenopus tropicalis

Alignment Length:	829	Identity:	275/829 - (33%)
Similarity:	493/829 - (59%)	Gaps:	11/829 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NIEYIQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFE 91
            |.||      |:.:|:    |:::||.||.:|.:||::::||:.:|..:.::|||..|.|..|.|
Frog   265 NKEY------LAHIEE----LEEELEAERNIRAKIEKQRSDLANEVDDLHDKLEETAGFASSQVE 319

  Fly    92 ANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTE 156
            .|:||:.||::||:.||:..|:||.|...|:|||...:.:..||.|.:.:.:.:.||:|...:.|
Frog   320 INKKREVELVRLRQELEEALLQSEGTASALRKKHAASLVEATEQHESMQRARMKLEKEKQNLKGE 384

  Fly   157 VYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQ 221
            :.||.:..|:..|.|..|:..:.|:|..:||.|.|.|||.:.:.|.::.:::|..||.:|:..|:
Frog   385 LEELAATAENLQKAKTSSDAQLRKMEDLLSEANYKNEELQKLITDQNNSKNKLFVENSDLSHQVE 449

  Fly   222 DLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDL 286
            :|:.::..::.:|..:.||.||.:::|::|.:.::....:|..:::|.:.::.|||||.|::.:|
Frog   450 ELESRISQLNRTKLLLASQTEDLKKQLDEETKAKTTALGNLGNLKLECELLKEQLEEELESKSEL 514

  Fly   287 ERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLA 351
            :||:.|.|:|.|.|:.::.:|...|.||:||.::|...|:.|.||.:|:..:|.:||||.|.||.
Frog   515 QRQISKLNSDNTHWRTRYENEAIHRTEELEETKKKLTARLQEAEEAVEATQMKCSNLEKTKQRLQ 579

  Fly   352 SEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHE 416
            .|:|.:.:||||:|.:...|.|....::|...|.:.:.::.....:.||::.:....:|.:....
Frog   580 GEIEDVCMDLEKANTASEALDKKQRMIDKQITEWRQKFEDVHSSLDASQKECRLYTTELFKIKTA 644

  Fly   417 LDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRK 481
            .::..:....|.||||.|.:::.:....:.:..:...||:...::.|.|::|:..||:||||..:
Frog   645 FEETHEQVMALKRENKTLQEEIADLTEQLRDAGKNTLELQKSKKKSEMEKEEMQVAYEEAEAALE 709

  Fly   482 AEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKK 546
            .||.:..||..:..|.:.|.:||:.:|:||:||.||.....:|.|.|. ::.|.:.:.|.||:||
Frog   710 VEEAKVVRLQLEITQLKADIDRRVQDKEEELEATRKNHQRTLESLQAS-LDTEVKGRAEATRLKK 773

  Fly   547 KLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGL 611
            ||:..|.|||:.|:.:||...:|.|::|||..||.:||...|:...|.:..:::..:.:||...|
Frog   774 KLENDINELEIQLENSNKNTGELVKLVKKQQQQLKDLQTQMEEEAHQHEQEIEERNLLERRNGVL 838

  Fly   612 NGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSK 676
            ..||||:|:.:::::|:::..|.:..|.:.:.|||......:...|.|.:..:..|.::.|::..
Frog   839 VSELEELRNAVEASDRSQKAQEQELMEISEKCNELQNQLQCISLAKKKQDANMQQVTAENEDLLN 903

  Fly   677 ELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRI 741
            |||.::||.:|...|...:.|::|.||:....|:.|||.||.:::.|:..:||.|...:...|::
Frog   904 ELRNAEERAKKSAAETSRIAEELHHEQDLTHHLQKIKKGLESQIRELNANIEEAEQMTLKDGKKL 968

  Fly   742 ISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKIN 806
            |.|||.::::||.|||.|:::||||.|.|:|.||.:||::.|.|||||.....|:.:::..:|:.
Frog   969 IQKLEGKVKELETELELEQKKHAETTKTLKKYERRMKELVFQAEEDQKTQQRSQELVERLQSKLK 1033

  Fly   807 IYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHR 855
            .|:|...|.|..:.....:.|:...||:.||:|||.||::|:.||.|:|
Frog  1034 TYKRMAEEAEEQANLNLNKYRKTINELDDAEERADIAEAALSKIRTKNR 1082

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	270/818 (33%)
LOC100495690	XP_031750519.1	Myosin_tail_1	<229..1080	CDD:396244	273/825 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22988
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010