Protein Alignment h and HES7

DIOPT Version :9

• Sequence 1: NP_001014577.1
• Gene: h / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_016880721.1
• Gene: HES7 / 84667
• HGNCID: 15977
• Length: 265
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 78/365 - (21%)
• Similarity: 114/365 - (31%)
• Gaps: 129/365 - (35%)

  Fly     1 MVTGVTAANMTNVLGTAVVPAQLKETPLKS---------DRRSN-------KPIMEKRRRARINN 49
            |..|..:..:...||...:..|....|:.:         ||..|       ||::|||||.|||.
Human     1 MSKGAGSGPIPPTLGPRNIRLQASREPVHTGSGGAMVTRDRAENRDGPKMLKPLVEKRRRDRINR 65

  Fly    50 CLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQQAADP-----------KI 103
            .|.||:.|:|:.|:....|:.|||||:|||..|.:|:|  |.:.....||.|           .:
Human    66 SLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRE--RSRVEPPAAAAPGVPRSPVQDAEAL 128

  Fly   104 VNKFKAGFADCVNEVSRFP-GIEPAQRRRLLQHLSNCINGVKTELHQQQRQQQQQSIHAQMLPSP 167
            .:.:.:||.:|:..::.|. ...||.|.:|.                       .::|..:.|.|
Human   129 ASCYLSGFRECLLRLAAFAHDASPAARAQLF-----------------------SALHGYLRPKP 170

  Fly   168 PSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQ 232
            |.....|.:..|..|
Human   171 PRPKPVDPRPPAPRP-------------------------------------------------- 185

  Fly   233 QQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANS 297
                .|..||.|...|..|:.|:....|....:...:.....||...||...:.....||.|...
Human   186 ----SLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQ 246

  Fly   298 SYEPMDIKPSVIQRVPMEQQPLSLVIKKQIKEEEQPWRPW 337
            ...|         :.|:...|..             ||||
Human   247 DGAP---------KAPLPPPPAF-------------WRPW 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
h	NP_001014577.1	HLH	29..88	CDD:238036	30/74 (41%)
		ORANGE	106..141	CDD:128787	8/35 (23%)
HES7	XP_016880721.1	HLH	49..108	CDD:238036	29/60 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810