DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment h and hes2.2

DIOPT Version :9

Sequence 1:	NP_001014577.1	Gene:	h / 38995	FlyBaseID:	FBgn0001168	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001038818.1	Gene:	hes2.2 / 751634	ZFINID:	ZDB-GENE-060825-55	Length:	172	Species:	Danio rerio

Alignment Length:	157	Identity:	55/157 - (35%)
Similarity:	83/157 - (52%)	Gaps:	25/157 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQ 96
            |::.||::||:||||||:.|:.||.|||..|.||..|:||||||||||.||:.|.::|     ..
Zfish     9 RKTLKPLLEKKRRARINDSLDRLKALILPLTGKDNCRYSKLEKADILEMTVRFLTDIQ-----TT 68

  Fly    97 QAADPKIVNKFKAGFADCVNEVS-RFP--GIEPAQRRRLLQHL-----------SNCINGVKTEL 147
            .:.|..:  .|..|:..|:..|| |.|  .::...|.|:...:           .||.  .::..
Zfish    69 PSKDTAV--SFTEGYTTCLQRVSARLPQTSLDAETRHRVNDFIQRSVMPKTPACQNCC--AQSSR 129

  Fly   148 HQQQRQQQQQSIHAQMLPSPPSSPEQD 174
            ...|.||:.|::.:.  .|..::|:||
Zfish   130 MMSQIQQKLQNLKSS--SSRSTNPKQD 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
h	NP_001014577.1	HLH	29..88	CDD:238036	34/55 (62%)
h	NP_001014577.1	ORANGE	106..141	CDD:128787	11/48 (23%)
hes2.2	NP_001038818.1	HLH	6..67	CDD:238036	35/62 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1427802at2759
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920