DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment h and hes5.1

DIOPT Version :9

Sequence 1:	NP_001014577.1	Gene:	h / 38995	FlyBaseID:	FBgn0001168	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001037880.1	Gene:	hes5.1 / 733463	XenbaseID:	XB-GENE-481135	Length:	154	Species:	Xenopus tropicalis

Alignment Length:	157	Identity:	52/157 - (33%)
Similarity:	75/157 - (47%)	Gaps:	30/157 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KSDRRSNKPIMEKRRRARINNCLNELKTLI-LDATKKDPARHSKLEKADILEKTVKHLQELQRQQ 92
            |...:..|||:||.||.||||.:.:||.|: .:..|::|  :.|||||||||..|.:||:.:.|.
Frog    14 KEKNKLRKPIVEKMRRDRINNSIEQLKALLEKEFHKQEP--NVKLEKADILEMAVSYLQQQKSQS 76

  Fly    93 AAMQQAADPKIVNKFKAGFADCVNEVSRFPGIEPAQ---RRRLLQHLSNCINGVKTELHQQQRQQ 154
            ..:     .|:...:|.||:.|:.|..:|....|..   :.:||:||                 |
Frog    77 PNL-----AKLEQDYKQGFSSCLREAVQFLCYYPESGETQMKLLKHL-----------------Q 119

  Fly   155 QQQSIHAQMLPSPPSSPEQDSQQGAAA 181
            ..|.:....|...||  ..||:|.|.|
Frog   120 APQKLSVAPLTYIPS--VSDSKQAALA 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
h	NP_001014577.1	HLH	29..88	CDD:238036	29/59 (49%)
h	NP_001014577.1	ORANGE	106..141	CDD:128787	11/37 (30%)
hes5.1	NP_001037880.1	HLH	14..75	CDD:238036	29/62 (47%)
hes5.1	NP_001037880.1	Hairy_orange	84..121	CDD:295407	12/53 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910