Protein Alignment h and Heyl

DIOPT Version :9

• Sequence 1: NP_001014577.1
• Gene: h / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_038933.2
• Gene: Heyl / 56198
• MGIID: 1860511
• Length: 326
• Species: Mus musculus
• Alignment Length: 322
• Identity: 83/322 - (25%)
• Similarity: 126/322 - (39%)
• Gaps: 84/322 - (26%)

  Fly    16 TAVVPAQLKETPLKSDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEK 80
            |...|:|::.      |:..:.|:|||||.|||:.|:||:.|:..|.:|..:  ||||||::|:.
Mouse    34 TTPSPSQMQA------RKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQM 90

  Fly    81 TVKHLQELQRQQAAMQQAADPKIVNKFKAGFADCVNEVSRFPGI--------EPAQRRRLLQHLS 137
            ||.||:.|..........|....|:....||.:|:.||.|:.|:        :|. |.|||.||
Mouse    91 TVDHLKMLHASGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSHADPV-RIRLLSHL- 153

  Fly   138 NCINGVKTELHQQQRQQQQQSIHAQMLPSP-------------------PSSPEQDSQQGAAAPY 183
                               :|..|:|.|||                   |..|..:||
Mouse   154 -------------------KSYAAEMEPSPTTTSALAFPVWPWSFLHSCPGLPSLNSQ------- 192

  Fly   184 LFGIQQTASGYFLP---------NGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLA 239
             ..|.....|..||         :.::..|...|.|:|.......||.:......:....::..|
Mouse   193 -LAILGRVPGPVLPSISSPPYPISALRSAPVHRPAGTIPPTRRNLLPSRGVTSTQRAHLPERPAA 256

  Fly   240 VAAAAAAAAAAQQQPMLVSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEP 301
            ....|..|.||:.   :|.:|..:.:|...:..|.   ::..||.||     |.|:..:..|
Mouse   257 PPPTALDARAARS---IVPIPPCSPTTAPGAGKSD---DNVSGSISS-----PCPSGPTGRP 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
h	NP_001014577.1	HLH	29..88	CDD:238036	27/58 (47%)
		ORANGE	106..141	CDD:128787	14/42 (33%)
Heyl	NP_038933.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		8/27 (30%)
		Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250	42..111		29/76 (38%)
		HLH	44..100	CDD:238036	28/57 (49%)
		ORANGE	115..162	CDD:128787	17/67 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	223..260		6/36 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	272..306		9/41 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830923
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740