Protein Alignment h and Hes6

DIOPT Version :9

• Sequence 1: NP_001014577.1
• Gene: h / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_062352.1
• Gene: Hes6 / 55927
• MGIID: 1859852
• Length: 224
• Species: Mus musculus
• Alignment Length: 325
• Identity: 77/325 - (23%)
• Similarity: 111/325 - (34%)
• Gaps: 139/325 - (42%)

  Fly    29 KSDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQA 93
            :.||::.||::||:||||||..|.||: |:|..|:.    .:|||.|::||.||:.:|...|.:|
Mouse    23 RGDRKARKPLVEKKRRARINESLQELR-LLLAGTEV----QAKLENAEVLELTVRRVQGALRGRA 82

  Fly    94 AMQQAADPKIVNKFKAGFADCVNEVSRFPGIEPAQRRRLLQHLSNCINGVKTELHQQQRQQQQQS 158
            ..::....:...:|.||:..|::||..|              :|.|                 |:
Mouse    83 REREQLQAEASERFAAGYIQCMHEVHTF--------------VSTC-----------------QA 116

  Fly   159 IHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQ 223
            |.|                            |.|.
Mouse   117 IDA----------------------------TVSA------------------------------ 123

  Fly   224 QQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTAST-GSASSHSSAGYESAPGSSSSC 287
               :||.|                       :|.|||.|..|: ......|.||   .||.|...
Mouse   124 ---ELLNH-----------------------LLESMPLREGSSFQDLLGDSLAG---LPGGSGRS 159

  Fly   288 SY----APPSPANSSYEPMD--------IKPSVIQRVPMEQQPL---SLVIKKQIKEEEQPWRPW 337
            |:    :|.||.:|...|.|        |..:.:.|||.|...|   ||......:..:..||||
Mouse   160 SWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVSTSLGSLTAARRAQSVWRPW 224

  Fly   338  337
            Mouse   225  224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
h	NP_001014577.1	HLH	29..88	CDD:238036	27/58 (47%)
		ORANGE	106..141	CDD:128787	9/34 (26%)
Hes6	NP_062352.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		2/7 (29%)
		bHLH_SF	24..81	CDD:412148	28/61 (46%)
		Hairy_orange	96..134	CDD:400076	19/152 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..209		20/65 (31%)
		WRPW motif	221..224		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810