Protein Alignment hry and hey1

DIOPT Version :10

• Sequence 1: NP_523977.2
• Gene: hry / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001007911.1
• Gene: hey1 / 493293
• XenbaseID: XB-GENE-486694
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 296
• Identity: 77/296 - (26%)
• Similarity: 116/296 - (39%)
• Gaps: 78/296 - (26%)

  Fly    32 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQ 96
            |:..:.|:|||||.||||.|:||:.|:..|.:|..:  :|||||:||:.||.||:.|........
 Frog    49 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTAGGKGY 111

  Fly    97 QAADPKIVNKFKAGFADCVNEVSRFPGI-------EPAQRRRLLQHLSN------CINGVKTEL- 147
            ..|....::....||.:|:.||:|:..|       :|. |.||:.||:|      ..|...|.:
 Frog   112 FDAHALAMDYRSLGFRECLAEVARYLSIIEGMDTTDPL-RVRLVSHLNNYASQREAANTAHTGIG 175

  Fly   148 ------------HQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGM 200
                        |........|:.|.....:..|:......:...:|:    .:|:|
 Frog   176 HIPWGGTFAHHPHLSHPLLLAQTAHTSANSTSSSTEAHHQNRLPGSPH----AETSS-------- 228

  Fly   201 QVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTAS 265
            ..:|   |||:||.|||                           ..|::....|:|.||...:|.
 Frog   229 LRVP---PNGNIASVLP---------------------------VVASSKLSPPLLSSMASLSAF 263

  Fly   266 TGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEP 301
            ..|..|....       |.:|.|...|:|:...|.|
 Frog   264 PFSFGSFHLL-------SPNSLSPTTPTPSGKPYRP 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hry	NP_523977.2	bHLH-O_hairy_like	30..88	CDD:381483	28/55 (51%)
		ORANGE	106..141	CDD:128787	14/47 (30%)
hey1	NP_001007911.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		1/2 (50%)
		bHLH_SF	40..121	CDD:469605	30/73 (41%)
		ORANGE	119..165	CDD:128787	14/46 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	199..232		5/44 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..300		5/15 (33%)
		YRPW motif	290..293		2/3 (67%)