Protein Alignment hry and ref-1

DIOPT Version :10

• Sequence 1: NP_523977.2
• Gene: hry / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_496204.1
• Gene: ref-1 / 174585
• WormBaseID: WBGene00004334
• Length: 367
• Species: Caenorhabditis elegans
• Alignment Length: 396
• Identity: 75/396 - (18%)
• Similarity: 128/396 - (32%)
• Gaps: 134/396 - (33%)

  Fly    23 LKETPLKSDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQE 87
            |..||..:...:.|...||:||..||..:.||:.||     ::.:.:.|:.:.|:|.:.|:.:..
 Worm     3 LISTPPPAYAHNRKTSQEKKRRDEINAKIKELQLLI-----QNESDNEKMTQGDVLNRAVEVVSR 62

  Fly    88 LQRQQAAMQQAADPKIVNKFKAGFAD----------------------CVNEVSRFPGIEPAQRR 130
            ::.:......       |..:.||.|                      |.:.|.|.......:|.
 Worm    63 METESPGPSS-------NPNRKGFFDGFRSIESLTYSFIKSLGVNSDVCQDFVQRAKQFFDRERS 120

  Fly   131 RLLQHLSNCINGVKTELHQQQRQQQQQSIHAQM-LPSPPSSP------------------EQD-- 174
            .||..:|.          :.:|:.:.:.:|:.| ..|..|||                  |||
 Worm   121 SLLSTVSG----------KSKRRSESEILHSSMSYRSQSSSPSTSESGITIDRKEVKKNREQDRR 175

  Fly   175 SQQGAAAPYL--FGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQ 237
            .:||.|...|  |.|:...........||.:.|      :.:::  :..|.::...:....|:|.
 Worm   176 DRQGEAFDALKNFIIENKLMTSHQVEKMQRLNT------LDIII--AYIQNKKHNFVSRSDQEQS 232

  Fly   238 LAVAAAAAAAAAAQQ-----------------------------QPM------------------ 255
            |...|.|.....|:.                             :|:
 Worm   233 LYAHAIAEGKKTAKNIAFQFFKSDRHLVVRCADLEKFFEFSLSPKPLFGFPSMPIPIPPPSFPIF 297

  Fly   256 ------LVSMPQRTASTGSASSHS-SAGYESAPGSSSSCSYAPPSPA----NSSYEPMDIKPSVI 309
                  ...||....:|...|..| |...:|.|.||.:.|.:..:|:    ||:..|...:.|.:
 Worm   298 PFRPFPFFPMPMAPMATSPKSQQSPSYSLDSPPPSSDTSSSSIETPSTPNENSNSNPKASRKSKL 362

  Fly   310 QRVPME 315
            .| |.|
 Worm   363 FR-PWE 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hry	NP_523977.2	bHLH-O_hairy_like	30..88	CDD:381483	15/57 (26%)
		ORANGE	106..141	CDD:128787	10/56 (18%)
ref-1	NP_496204.1	HLH	20..66	CDD:197674	14/50 (28%)
		HLH	170..217	CDD:197674	12/54 (22%)