Protein Alignment hry and Hes5

DIOPT Version :10

• Sequence 1: NP_523977.2
• Gene: hry / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_006538625.3
• Gene: Hes5 / 15208
• MGIID: 104876
• Length: 415
• Species: Mus musculus
• Alignment Length: 245
• Identity: 61/245 - (24%)
• Similarity: 100/245 - (40%)
• Gaps: 79/245 - (32%)

  Fly    13 VLGT----AVVPAQLKETPLKS-----------------------DRRSNKPIMEKRRRARINNC 50
            |||:    :..|..::..||:|                       ..|..||::||.||.|||:.
Mouse   189 VLGSRSRQSGTPGSVRSAPLRSLIASRAPGMAPSTVAVEMLSPKEKNRLRKPVVEKMRRDRINSS 253

  Fly    51 LNELKTLILDATKKDPARH---SKLEKADILEKTVKHLQELQ----------------------- 89
            :.:||.|:    :::.|||   ||||||||||..|.:|:..:
Mouse   254 IEQLKLLL----EQEFARHQPNSKLEKADILEMAVSYLKHSKGEPGACARLLLPADVAPTARAPL 314

  Fly    90 ---RQQAAMQQAADPKIVNK-FKAGFADCVNEVSRFPGIEPAQ--RRRLLQHLSNCINGVKTELH 148
               |...|...||.||.::: :..|::.|:.|..:|..:..|.  :.:||.|.
Mouse   315 MPLRLPTAFAAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHF------------ 367

  Fly   149 QQQRQQQQQSIHAQMLPSPPSSPE-QDSQQGAAAPYLFGIQQTASGYFLP 197
               ::....:..|:..|:|.::|: ..|...|||..:...:|.|.|.:.|
Mouse   368 ---QRPPAPAAPAKEPPAPGAAPQPARSSAKAAAAAVSTSRQPACGLWRP 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hry	NP_523977.2	bHLH-O_hairy_like	30..88	CDD:381483	29/83 (35%)
		ORANGE	106..141	CDD:128787	8/37 (22%)
Hes5	XP_006538625.3	bHLH-O_HES5	236..292	CDD:381467	28/59 (47%)
		ORANGE	334..369	CDD:128787	8/49 (16%)