DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pex7 and pex7

DIOPT Version :9

Sequence 1:	NP_001137914.1	Gene:	Pex7 / 38994	FlyBaseID:	FBgn0035922	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001343038.1	Gene:	pex7 / 5802962	PomBaseID:	SPAC17D4.01	Length:	308	Species:	Schizosaccharomyces pombe

Alignment Length:	316	Identity:	94/316 - (29%)
Similarity:	153/316 - (48%)	Gaps:	33/316 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GYSLRFSPFEANYLLLATSQLYGLAGGGSLFLLEQNSNTNSSSTDGQSLG-ELCR-LEWSDGLFD 75
            |.|::|||...|.:.:|....|||.|.|.|::           .|....| ::|: .:..|.||.
pombe    11 GESVQFSPLVENKIAVAAVTHYGLGGSGRLYI-----------HDVTPKGIQVCQHYDVEDSLFG 64

  Fly    76 VAWCPYAADIAATASGDGSLQIWCGLDGESASNQLT-PKQPLICLQEHKNEVYSLDWGEKWNYHT 139
            |.|.....:......|||||:::          .|| |.:|:...:|||.|:.::|.... :...
pombe    65 VRWSQNCENQVYACCGDGSLRLF----------DLTMPSKPIHKWKEHKAEIVAIDTNTV-DRRI 118

  Fly   140 LLSGSWDCTLKLWDCNRQNSITTF-VGHNDLIYGAKFSPLIANLFASVSTDGHLNLWNSLDF-AG 202
            :::||||.|:|||..|..||:.|. .|.|..|..........||....|:||....|   || :.
pombe   119 VVTGSWDGTIKLWLGNLPNSVQTLNNGSNSRILTVATHYSSPNLLGYTSSDGLCKFW---DFRSS 180

  Fly   203 KPLMSIEAHASEALCCDWSHFDRNVLVTGGSDGLIRGWDLRKMRTHVFELYSGEFAVRRLACSPH 267
            ...||||. .::..|.:||..:..::.|..::.|:..:|:..::|.:..|...:.|||.:..|..
pombe   181 DKFMSIEI-PNQITCMNWSKSNHRMVYTADNNNLVYCYDIANLKTPLSVLSGHQLAVRSIKSSNS 244

  Fly   268 SAAVLASANYDFTTRIWNLERGESAQEVNARHTEFVCGLDWNPHRTHQ-LADCGWD 322
            :..:||:|:||.|:||::.|:....::|:. |:|||..:||:...... :|..|||
pombe   245 AHDLLATASYDMTSRIFDPEQHSCIRKVDL-HSEFVRDVDWSDFGDGSWIASVGWD 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex7	NP_001137914.1	WD40	53..328	CDD:295369	81/276 (29%)
		WD40 repeat	74..121	CDD:293791	12/47 (26%)
		WD40	<85..>328	CDD:225201	73/242 (30%)
		WD40 repeat	126..164	CDD:293791	13/38 (34%)
		WD40 repeat	171..209	CDD:293791	10/38 (26%)
		WD40 repeat	215..251	CDD:293791	7/35 (20%)
		WD40 repeat	259..296	CDD:293791	12/36 (33%)
		WD40 repeat	303..328	CDD:293791	7/21 (33%)
pex7	NP_001343038.1	WD40	35..>306	CDD:225201	84/292 (29%)
		WD40 repeat	65..101	CDD:293791	11/45 (24%)
		WD40 repeat	106..143	CDD:293791	13/37 (35%)
		WD40 repeat	151..185	CDD:293791	8/36 (22%)
		WD40 repeat	192..230	CDD:293791	7/37 (19%)
		WD40 repeat	236..273	CDD:293791	12/36 (33%)
		WD40 repeat	279..305	CDD:293791	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0277
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I1514
OMA	1	1.010	-	-		QHG53887
OrthoFinder	1	1.000	-	-		FOG0006273
OrthoInspector	1	1.000	-	-		oto101034
orthoMCL	1	0.900	-	-		OOG6_102912
Panther	1	1.100	-	-	LDO	PTHR46027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R904
SonicParanoid	1	1.000	-	-		X5222
TreeFam	1	0.960	-	-
	12	11.860