DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex7 and Pex7

DIOPT Version :9

Sequence 1:	NP_001137914.1	Gene:	Pex7 / 38994	FlyBaseID:	FBgn0035922	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001029319.1	Gene:	Pex7 / 308718	RGDID:	1308483	Length:	318	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	137/324 - (42%)
Similarity:	185/324 - (57%)	Gaps:	20/324 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RHGYSLRFSPFEANYLLLATSQLYGLAGGGSLFLLEQNSNTNSSSTDGQSLGELCRLEWSDGLFD 75
            ||||::.|||:....|..|.:|.||:||.|:|.:|:||.:         .|......:|:|||||
  Rat    12 RHGYAVEFSPYLPGRLACAAAQHYGIAGCGTLLVLDQNES---------GLQIFRSFDWNDGLFD 67

  Fly    76 VAWCPYAADIAATASGDGSLQIWCGLDGESASNQLTPKQPLICLQEHKNEVYSLDWGEKWNYHTL 140
            |.|......:..|.|||||||:|   |...|:.      ||...:||..||||:||.:..:...:
  Rat    68 VTWSENNEHVLVTCSGDGSLQLW---DTAKATG------PLQVYKEHTQEVYSVDWSQTRDEQLV 123

  Fly   141 LSGSWDCTLKLWDCNRQNSITTFVGHNDLIYGAKFSPLIANLFASVSTDGHLNLWNSLDFAGKPL 205
            :|||||.|:|:||....||:.||.||..:||...:||.|...|||.|.|..|.:|: :...|..:
  Rat   124 VSGSWDQTVKVWDPTVGNSLCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWD-VKTTGVRI 187

  Fly   206 MSIEAHASEALCCDWSHFDRNVLVTGGSDGLIRGWDLRKMRTHVFELYSGEFAVRRLACSPHSAA 270
            : |.||.:|.|.|||..::.|:||||..|..:||||||.:|..||||....:|:||:..||..|:
  Rat   188 V-IPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHAS 251

  Fly   271 VLASANYDFTTRIWNLERGESAQEVNARHTEFVCGLDWNPHRTHQLADCGWDSLANVYTPQCLS 334
            ||||.:||||.|.||..:.:...|....||||.||||.:.....::|||.||....:|.|.||:
  Rat   252 VLASCSYDFTVRFWNFSKPDPLLETVEHHTEFTCGLDLSLQSPTEVADCSWDETVKIYNPVCLA 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex7	NP_001137914.1	WD40	53..328	CDD:295369	114/274 (42%)
		WD40 repeat	74..121	CDD:293791	17/46 (37%)
		WD40	<85..>328	CDD:225201	105/242 (43%)
		WD40 repeat	126..164	CDD:293791	17/37 (46%)
		WD40 repeat	171..209	CDD:293791	12/37 (32%)
		WD40 repeat	215..251	CDD:293791	18/35 (51%)
		WD40 repeat	259..296	CDD:293791	17/36 (47%)
		WD40 repeat	303..328	CDD:293791	9/24 (38%)
Pex7	NP_001029319.1	WD40 repeat	15..60	CDD:293791	16/44 (36%)
		WD40	<41..311	CDD:225201	114/269 (42%)
		WD40	63..310	CDD:238121	108/246 (44%)
		WD40 repeat	65..104	CDD:293791	17/38 (45%)
		WD40 repeat	110..148	CDD:293791	14/37 (38%)
		WD40 repeat	153..190	CDD:293791	17/36 (47%)
		WD40 repeat	197..234	CDD:293791	14/36 (39%)
		WD40 repeat	240..278	CDD:293791	20/37 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0277
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H242
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3027
OMA	1	1.010	-	-		QHG53887
OrthoDB	1	1.010	-	-		D350307at33208
OrthoFinder	1	1.000	-	-		FOG0006273
OrthoInspector	1	1.000	-	-		oto96649
orthoMCL	1	0.900	-	-		OOG6_102912
Panther	1	1.100	-	-	LDO	PTHR46027
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5222
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770