DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arr2 and arr3b

DIOPT Version :9

Sequence 1:	NP_523976.1	Gene:	Arr2 / 38993	FlyBaseID:	FBgn0000121	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_957086.1	Gene:	arr3b / 796867	ZFINID:	ZDB-GENE-030616-74	Length:	362	Species:	Danio rerio

Alignment Length:	359	Identity:	142/359 - (39%)
Similarity:	214/359 - (59%)	Gaps:	16/359 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KVFKKATPNGKVTFYLGRRDFIDHIDYCDPVDGVIVVEPDYLKNRKVFGQLATTYRYGREEDEVM 70
            ||:||.:.||.:..|||||||:||::..|.||||:.::|..|..|||:.|||..:|||||:.:|:
Zfish     3 KVYKKTSGNGSLCLYLGRRDFVDHVESVDSVDGVLKIDPSGLNGRKVWVQLACAFRYGREDLDVI 67

  Fly    71 GVKFSKELILCREQIVPMTNPNMEMTPMQEKLVRKLGSNAYPFTFHFPPNSPSSVTLQQEGDDNG 135
            ||.|.|::.:.|.|:.|........|||||.|::|.|...:||||..|.:.|.||:||...:|.|
Zfish    68 GVSFRKDIWIKRIQMYPFEGTKPPNTPMQEALLKKAGDQGHPFTFDIPVHLPCSVSLQPAPEDAG 132

  Fly   136 KPLGVEYTIRAFVGDSE---DDRQHKRSMVSLVIKKLQYAP--LNRGQRLPSSLVSKGFTFSNGK 195
            ||.||:|.::|::.:.|   |::..|:....|:|:|:||||  |..|   |.:.::|.|..::..
Zfish   133 KPCGVDYEVKAYIANEEDNIDEKVEKKDTCRLIIRKIQYAPAELAAG---PKADINKQFITADKP 194

  Fly   196 ISLEVTLDREIYYHGEKTAATVQVSNNSKKSVKSIKCFIVQHTEITMVNAQFSKHVAQLETKEGC 260
            |.:||::::|:||||:.....|:|:|.:.|.||.||..|.|.|:: ::.|....|...|..:.|.
Zfish   195 IHMEVSMEKELYYHGDPIPIKVKVNNETSKVVKKIKINIFQITDV-VIYAADKYHKCVLNEEFGD 258

  Fly   261 PITPGANLTKTFYLIPLAANNKDRHGIALDGHLKDEDVNLASSTMVQEGKSTGDACGIVISYSVR 325
            .|...:...|.:.:.||..|||::.|:||||.|||||.||||||::...... ...|:|:||.::
Zfish   259 QINANSTFEKEYSVTPLLVNNKEKRGLALDGRLKDEDTNLASSTLLIPDMDK-QMQGVVVSYKIK 322

  Fly   326 I--KLNCGTLGGEMQTDV----PFKLLQPAPGTI 353
            :  .:..|.||....:||    |..|:.|.|..|
Zfish   323 VILMMGGGLLGSLTSSDVTAELPLVLMSPKPAEI 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr2	NP_523976.1	Arrestin_N	17..172	CDD:278754	68/157 (43%)
Arr2	NP_523976.1	Arrestin_C	192..350	CDD:214976	58/163 (36%)
arr3b	NP_957086.1	Arrestin_N	16..172	CDD:278754	68/155 (44%)
arr3b	NP_957086.1	Arrestin_C	192..353	CDD:214976	58/162 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030