DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arr2 and saga

DIOPT Version :9

Sequence 1:	NP_523976.1	Gene:	Arr2 / 38993	FlyBaseID:	FBgn0000121	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_956853.1	Gene:	saga / 792319	ZFINID:	ZDB-GENE-040426-1538	Length:	392	Species:	Danio rerio

Alignment Length:	383	Identity:	157/383 - (40%)
Similarity:	239/383 - (62%)	Gaps:	13/383 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFKKATPNGKVTFYLGRRDFIDHIDYCDPVDGVIVVEPDYLKNRKVFGQLATTYRYGREED-EVM 70
            ||||.:.:..|..|:|:|||:|.:|..|||||||:::|:.|:.:|.:..|:..:||||::| ||:
Zfish     7 VFKKISKDKSVGVYMGKRDFVDRVDSVDPVDGVILIDPEQLRGKKAYVTLSCVFRYGRDDDAEVL 71

  Fly    71 GVKFSKELILCREQIVPMTNPNME--MTPMQEKLVRKLGSNAYPFTFHFPPNSPSSVTLQQEGDD 133
            |:.|.||:.:...|:.|......:  :|.:||||:||||.|||||.|.||.|.|.||.||....|
Zfish    72 GISFRKEIYISTRQVYPALQDKEQCILTKVQEKLLRKLGDNAYPFFFEFPDNLPCSVGLQPAPKD 136

  Fly   134 NGKPLGVEYTIRAFVGDSEDDRQHKRSMVSLVIKKLQYAPLNRGQRLPSSLVSKGFTFSNGKISL 198
            .||...||:.::||..:|:|.:..|||.|.|:|:|:||||...|. .||...::.|..|:..:.|
Zfish   137 VGKHCAVEFEVKAFCAESQDAKVRKRSSVGLMIRKVQYAPEKLGP-APSVETTRDFLMSDKPLHL 200

  Fly   199 EVTLDREIYYHGEKTAATVQVSNNSKKSVKSIKCFIVQHTEITM-VNAQFSKHVAQLETKEGCPI 262
            |.:|:::.|||||.....|:::|.|.|:|::|...:.|:..:.: .|..:.|.||..::  |..:
Zfish   201 EASLEKQTYYHGEPINVRVKINNQSNKNVRNIILSVEQNANVVLYCNDNYMKVVATEDS--GHSV 263

  Fly   263 TPGANLTKTFYLIPLAANNKDRHGIALDGHLKDEDVNLASSTMVQEGKSTGDACGIVISYSVRIK 327
            ..||.|.|.:.|:||.|||::|.||||||.||.||.|||||::::||... :..||::||.|.:|
Zfish   264 DSGAKLEKVYTLLPLLANNRERRGIALDGKLKHEDTNLASSSIIKEGVQK-EVLGIMVSYRVVVK 327

  Fly   328 LNCGTLGG--EMQTDVPFKLLQPAPGTIEKKRSNAMKKMKSIEQHRN-VKGYYQDDDD 382
            |..|.:.|  |:..::||:|:.|.|..:  |.|.|.::|...|..|. :||..:|:|:
Zfish   328 LIVGGMMGSSEVGVELPFQLMHPKPDAV--KESEAEEEMVFEEFKRTYLKGMPEDEDE 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr2	NP_523976.1	Arrestin_N	17..172	CDD:278754	72/157 (46%)
Arr2	NP_523976.1	Arrestin_C	192..350	CDD:214976	63/160 (39%)
saga	NP_956853.1	Arrestin_N	17..175	CDD:304627	72/157 (46%)
saga	NP_956853.1	Arrestin_C	194..352	CDD:214976	63/160 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3865
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930