DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arr2 and Arr3

DIOPT Version :9

Sequence 1:	NP_523976.1	Gene:	Arr2 / 38993	FlyBaseID:	FBgn0000121	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_001177922.1	Gene:	Arr3 / 171107	RGDID:	621385	Length:	381	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	142/400 - (35%)
Similarity:	239/400 - (59%)	Gaps:	36/400 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFKKATPNGKVTFYLGRRDFIDHIDYCDPVDGVIVVEPDYLKNRKVFGQLATTYRYGREEDEVMG 71
            ||||.:.|||.:.|||:|||:|.:|..:|:||||:|:|:|||.||:|.:|...:||||::.:|:|
  Rat     4 VFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVILVDPEYLKGRKMFVRLTCAFRYGRDDLDVIG 68

  Fly    72 VKFSKELILCREQIVPMTNPNME--MTPMQEKLVRKLGSNAYPFTFHFPPNSPSSVTLQQEGDDN 134
            :.|.|:|.:..:|:.|....:::  :|.:||:|:.|||.||||||.....|.|.|||||...:|:
  Rat    69 LTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPEDS 133

  Fly   135 GKPLGVEYTIRAFVGDSEDDRQHKRSMVSLVIKKLQYAPLNRGQRLPSSLVSKGFTFSNGKISLE 199
            |||.||::.:::|..::.:::..|...|.||::|:|::.|..|.. |.:...:.|..|:..:.|:
  Rat   134 GKPCGVDFEVKSFCAENLEEKISKSDSVQLVVRKVQFSALEPGPG-PWAQTIRSFFLSSQPLQLQ 197

  Fly   200 VTLDREIYYHGEKTAATVQVSNNSKKSVKSIKCFIVQHTEITMVNA-QFSKHVAQLETKEGCPIT 263
            ..:|||::||||..:..|.::|.:.|.::.||..::|.|::.:.:. :::|.|...|..|  .:.
  Rat   198 AWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVIQITDVVLYSLDKYTKTVFIREFTE--TVA 260

  Fly   264 PGANLTKTFYLIPLAANNKDRHGIALDGHLKDEDVNLASSTMVQEGKSTGDACGIVISYSVRIKL 328
            ..::.::||.:.||.|.|:.:.|:||||.||.||.||||||:::.|.:. :..||::||.|::.|
  Rat   261 ANSSFSQTFAVTPLLAANRQKQGLALDGKLKHEDTNLASSTILRPGMNK-ELLGILVSYKVKVNL 324

  Fly   329 NC---GTLGGEMQTDV----PFKLLQPAPGTIEKKRSNAMKKMKSIEQHRNVKGYYQDDDDNIVF 386
            ..   |.|||...:||    |..|:.|.|...|:..:.:                    .::||.
  Rat   325 MVSYGGILGGLPASDVGVELPLILIHPKPPHGERAVATS--------------------SEDIVV 369

  Fly   387 EDFAKMRMNN 396
            |:|  |:.|:
  Rat   370 EEF--MQQNS 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr2	NP_523976.1	Arrestin_N	17..172	CDD:278754	66/156 (42%)
Arr2	NP_523976.1	Arrestin_C	192..350	CDD:214976	57/165 (35%)
Arr3	NP_001177922.1	Arrestin_N	14..171	CDD:278754	66/156 (42%)
Arr3	NP_001177922.1	Arrestin_C	190..353	CDD:214976	57/165 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920