Protein Alignment Arr2 and Arr3

DIOPT Version :10

• Sequence 1: NP_523976.1
• Gene: Arr2 / 38993
• FlyBaseID: FBgn0000121
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: XP_006527925.1
• Gene: Arr3 / 170735
• MGIID: 2159617
• Length: 494
• Species: Mus musculus
• Alignment Length: 399
• Identity: 138/399 - (34%)
• Similarity: 227/399 - (56%)
• Gaps: 53/399 - (13%)

  Fly     6 KVFKKATPNGKVTFYLGRRDFIDHIDYCDPVDGVIVVEPDYLKNRK-VFGQLATTYRYGREEDEV 69
            :||||.:.|||.:.|||:|||:|.:|..:|:|||::|:|:||:.|| ||.:|...:||||::.:|
Mouse    48 RVFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVVLVDPEYLEGRKSVFVRLTCAFRYGRDDLDV 112

  Fly    70 MGVKFSKELILCREQIVPMTNPNME--MTPMQEKLVRKLGSNAYPFTFHFPPNSPSSVTLQQEGD 132
            :|:.|.|:|.:..:|:.|....:::  :|.:||:|:.|||.||||||.....|.|.|||||...:
Mouse   113 IGLTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPE 177

  Fly   133 DNGKPLGVEYTIRAFVGDSEDDRQHKRSMVSLVIKKLQYAPLNRGQRLPSSLVSKGFTFSNGKIS 197
            |:|||.||::.:::|..::.:::..|...|.||::|:|::.|..|.. ||:...:.|..|:..:.
Mouse   178 DSGKPCGVDFEVKSFCAENLEEKIPKSDSVQLVVRKVQFSALEPGPG-PSAQTIRSFFLSSQPLQ 241

  Fly   198 LEVTLDREIYYHGEKTAATVQVSNNSKKSVKSIKC------------------------------ 232
            |:..:|||::||||..:..|.::|.:.|.::.||.
Mouse   242 LQAWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAGLSKYVVSSYHTRSYQRAVSWSHVGDQLI 306

  Fly   233 --------FIVQHTEITMVNA-QFSKHVAQLETKEGCPITPGANLTKTFYLIPLAANNKDRHGIA 288
                    .:||.|::.:.:. :::|.|...|..|  .:...::.::||.:.||.|.|..:.|:|
Mouse   307 GHLLSLTFSVVQTTDVVLYSLDKYTKTVFVQEFTE--TVAANSSFSQTFAVTPLLAANCQKQGLA 369

  Fly   289 LDGHLKDEDVNLASSTMVQEGKSTGDACGIVISYSVRIKLNC---GTLGGEMQTDV----PFKLL 346
            |||.||.||.||||||:::.|.:. :..||::||.||:.|..   |.|||...:||    |..|:
Mouse   370 LDGKLKHEDTNLASSTILRPGMNK-ELLGILVSYKVRVNLVVSYGGILGGLPASDVGVELPVILI 433

  Fly   347 QPAPGTIEK 355
            .|.|...|:
Mouse   434 HPKPSPGER 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arr2	NP_523976.1	Arrestin_N	17..172	CDD:425619	65/157 (41%)
		Arrestin_C	192..350	CDD:214976	59/203 (29%)
Arr3	XP_006527925.1	Arrestin_N	59..215	CDD:451447	64/155 (41%)
		Arrestin_C	236..437	CDD:214976	59/203 (29%)