DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arr2 and arrb2

DIOPT Version :9

Sequence 1:	NP_523976.1	Gene:	Arr2 / 38993	FlyBaseID:	FBgn0000121	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	XP_031753380.1	Gene:	arrb2 / 100101741	XenbaseID:	XB-GENE-481084	Length:	426	Species:	Xenopus tropicalis

Alignment Length:	402	Identity:	174/402 - (43%)
Similarity:	262/402 - (65%)	Gaps:	18/402 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SVKVFKKATPNGKVTFYLGRRDFIDHIDYCDPVDGVIVVEPDYLKNRKVFGQLATTYRYGREEDE 68
            :|:||||::||.|:|.|||:|||:||:|..||||||::|:.||||:|||:..|...:|||||:.:
Frog    24 AVRVFKKSSPNCKLTVYLGKRDFVDHLDRVDPVDGVVLVDTDYLKDRKVYVTLTCAFRYGREDLD 88

  Fly    69 VMGVKFSKELILCREQIV-PMTNPNMEMTPMQEKLVRKLGSNAYPFTFHFPPNSPSSVTLQQEGD 132
            |:|:.|.|:|.:.:.|.. |:......:|.:||:|::|||..|:||.|..|.|.|.|||||...:
Frog    89 VLGLSFRKDLFISKFQAYPPLPEEKKPLTRLQERLIKKLGEQAHPFFFTIPQNLPCSVTLQPGPE 153

  Fly   133 DNGKPLGVEYTIRAFVGDSEDDRQHKRSMVSLVIKKLQYAPLNRGQRLPSSLVSKGFTFSNGKIS 197
            |.||..||:|.||||...:.:::.|||:.|.|||:|:|:||...|.: |.:..::.|..|:..:.
Frog   154 DTGKACGVDYEIRAFCAKTMEEKMHKRNSVRLVIRKVQFAPEKPGPQ-PVAETTRHFLMSDRSLH 217

  Fly   198 LEVTLDREIYYHGEKTAATVQVSNNSKKSVKSIKCFIVQHTEITMVN-AQFSKHVAQLETKEGCP 261
            ||.:||:|:|||||.....|.|:|||.|:||.:|..:.|:.:|.:.: ||:...|||:|..:  .
Frog   218 LEASLDKELYYHGEPINVNVHVTNNSSKTVKRVKVSVRQYADICLFSTAQYKCPVAQIEQDD--Q 280

  Fly   262 ITPGANLTKTFYLIPLAANNKDRHGIALDGHLKDEDVNLASSTMVQEGKSTGDACGIVISYSVRI 326
            :||.:...|.:.|.||.:||:::.|:||||.||.||.||||||:|:|| |:.:..||::||.|::
Frog   281 VTPSSTFCKVYTLTPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEG-SSKEVLGILVSYRVKV 344

  Fly   327 KLNCGTLGGEMQTDVPFKLLQPAP------GTIEKKRSNAMKKMKSIEQHRNVKGYYQDDDDNIV 385
            || ..:.||::..::||.|:.|.|      ...|..:::|......||...|   :.||||  ||
Frog   345 KL-VVSRGGDVAVELPFVLMHPKPPENISRPLSEYPQTDAPVDTNLIEFDTN---FAQDDD--IV 403

  Fly   386 FEDFAKMRMNNV 397
            |||||::|:..:
Frog   404 FEDFARLRLKGL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr2	NP_523976.1	Arrestin_N	17..172	CDD:278754	75/155 (48%)
Arr2	NP_523976.1	Arrestin_C	192..350	CDD:214976	68/158 (43%)
arrb2	XP_031753380.1	Arrestin_N	37..193	CDD:395268	75/155 (48%)
arrb2	XP_031753380.1	Arrestin_C	212..367	CDD:214976	68/158 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110