Protein Alignment Cdc6 and ORC1A

DIOPT Version :10

• Sequence 1: NP_648247.1
• Gene: Cdc6 / 38989
• FlyBaseID: FBgn0035918
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_567440.1
• Gene: ORC1A / 827121
• AraportID: AT4G14700
• Length: 809
• Species: Arabidopsis thaliana
• Alignment Length: 860
• Identity: 189/860 - (21%)
• Similarity: 313/860 - (36%)
• Gaps: 311/860 - (36%)

  Fly    12 SISKATAASPLPPSTQTP-RRSEVWKRRQPKKVLADSDEEEEVVTAIYDLTSPVSENNENRNVLN 75
            |.|..:...|..|.|.|| |||   .|...:|:...:|.        .||  |..|:.|..|::.
plant    29 SPSSTSLTPPQTPETLTPLRRS---SRHVSRKINLGNDP--------IDL--PGKESVEEINLIR 80

  Fly    76 KMDKISRRRTSQVQVAQ-----------SELPKTP-RS-TKKTVQSAGSSRAKR----------- 116
            |    .|:||:.:.||:           |..|.:| || ||||      .:.||
plant    81 K----PRKRTNDIVVAEKSKKKKIDPEVSFSPVSPIRSETKKT------KKKKRVYYNKVEFDET 135

  Fly   117 -------------EEENREATARFLEGEQDSEV-------------------DPLHG-------- 141
                         |:.|.:.     |.|:|.|:                   |.|.|
plant   136 EFEIGDDVYVKRTEDANPDE-----EEEEDPEIEDCQICFKSHTNTIMIECDDCLGGFHLNCLKP 195

  Fly   142 ----------------------------SPPKQRKL-QPLPQHLISPSRLLDRLSIDERQEEEVE 177
                                        .||:.:|| :.:.:.|:|......|:   |:..:||:
plant   196 PLKEVPEGDWICQFCEVKKSGQTLVVVPKPPEGKKLARTMKEKLLSSDLWAARI---EKLWKEVD 257

  Fly   178 ATTH---------KTETAEQQPKHQAKDE-----------------------AKPRPKQQED--- 207
            ...:         ..||...:.:|..|.|                       .|...|...|
plant   258 DGVYWIRARWYMIPEETVLGRQRHNLKRELYLTNDFADIEMECVLRHCFVKCPKEFSKASNDGDD 322

  Fly   208 -------------------PLAQKQQEKPPTKQPNKNQTKEKSN--IQTNEETQQNNLPSPSRNK 251
                               .||...::........|.:..:.|:  |:.::|.....: |.|:..
plant   323 VFLCEYEYDVHWGSFKRVAELADGDEDSDQEWNGRKEEEIDYSDEEIEFDDEESVRGV-SKSKRG 386

  Fly   252 YQNARR--------------------------------VLNSAETQNLPGRESQLQELREFFSNH 284
            ..|:|:                                :|.:...::||.|..:::|:..|....
plant   387 GANSRKGRFFGLEKVGMKRIPEHVRCHKQSELEKAKATLLLATRPKSLPCRSKEMEEITAFIKGS 451

  Fly   285 L-ESQTSG-SLYVSGQPGTGKT-ACLSLLLRDPDFSKRLQR------------VYINCTSIASVG 334
            : :.|..| .:|:.|.|||||| :.||::       |.|:.            |.||...:||..
plant   452 ISDDQCLGRCMYIHGVPGTGKTISVLSVM-------KNLKAEVEAGSVSPYCFVEINGLKLASPE 509

  Fly   335 AVYKKLCTELQLKVSGRTE--RDHLEAIQRHLKTAKRM-------LLLVLDEIDQLCTSRQEVLY 390
            .:|..:...|    ||...  :..|:::.......|::       .:|::||:|.|.|..|.|||
plant   510 NIYSVIYEGL----SGHRVGWKKALQSLNERFAEGKKIGKENEKPCILLIDELDVLVTRNQSVLY 570

  Fly   391 TIFEWPALPGSRILLVGIANSLDLTDRALMRLNARCELKPRLMHFPPYSKQQIVEIFKSRLAEAE 455
            .|.:||..|.|:::::||||::||.::.|.|:::|..:: ||. |.||:.:|:.||..:||   |
plant   571 NILDWPTKPNSKLVVLGIANTMDLPEKLLPRISSRMGIQ-RLC-FGPYNHRQLQEIISTRL---E 630

  Fly   456 VLDVFPPVTLQLLAAKVSAISGDVRRALDIGRRVVEIAEQQKRDGEKEFNMKALQLEGKDAVEAK 520
            .::.|....::..:.||:|||||.||||:|.||..|:|         ::.:|      |..:.||
plant   631 GINAFEKTAIEFASRKVAAISGDARRALEICRRAAEVA---------DYRLK------KSNISAK 680

  Fly   521 EKQDTLKPVQVTQVAAVLNKVYGASQNLEEDIEASFPLQQKLMLCTLVLMLRNERNKDISMGRLH 585
            .:...:..|:|     .:.:::.|.   ...:..|.....::.|..:|                |
plant   681 SQLVIMADVEV-----AIQEMFQAP---HIQVMKSVSKLSRIFLTAMV----------------H 721

  Fly   586 EVYR---------RVCAKRNILALDQAE-FTG-------TVDLVETRGILRIMRKKEPRLHKVLL 633
            |:|:         ||....:.:.|...| |.|       ..||.|.|.:|....:|. ||.|:.|
plant   722 ELYKTGMAETSFDRVATTVSSICLTNGEAFPGWDILLKIGCDLGECRIVLCEPGEKH-RLQKLQL 785

  Fly   634 QWDEEEVHAALSDKQ 648
            .:..::|..||.|.:
plant   786 NFPSDDVAFALKDNK 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc6	NP_648247.1	CDC6	256..646	CDD:441083	116/462 (25%)
ORC1A	NP_567440.1	BAH_plant_2	187..341	CDD:240069	19/156 (12%)
		PTZ00112	<419..723	CDD:240274	94/358 (26%)