Protein Alignment Cdc6 and cdc6

DIOPT Version :10

• Sequence 1: NP_648247.1
• Gene: Cdc6 / 38989
• FlyBaseID: FBgn0035918
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001120805.1
• Gene: cdc6 / 402825
• ZFINID: ZDB-GENE-050506-131
• Length: 561
• Species: Danio rerio
• Alignment Length: 638
• Identity: 216/638 - (33%)
• Similarity: 326/638 - (51%)
• Gaps: 96/638 - (15%)

  Fly    24 PSTQTPRRSEVWKRRQPKKVLADSDEEEEVVTAIYDLTSPVSENNENRNVLNKMDKISRRRTSQV 88
            |:.|.|||.......:||    .|.|.:     :.|.|:|:|.  ....|.|.:......|...:
Zfish    10 PTLQFPRRKSSRLGSRPK----SSCENK-----VDDKTTPLSP--RKAIVGNSLGVCQSPRNKVL 63

  Fly    89 QVAQSE-LPKTPRSTKKTVQSAGSSRAKREEENREATARFLEGEQDSEVDPLHGSPPKQRKLQPL 152
            ....|| ||.:||  |:|....|.        |..|:              :.||||||| ..|
Zfish    64 NSPLSERLPLSPR--KRTGDENGC--------NLPAS--------------MLGSPPKQR-CAP- 102

  Fly   153 PQHLISPSRLLDRLSIDERQEEEVEATTHKTETAEQQPKHQAKDEAKPRPKQQEDPLAQKQQEKP 217
               |.||.    :||.:|           .|......|        :|.....:.||:
Zfish   103 ---LCSPR----KLSFNE-----------NTPVLSSPP--------RPILSSHKVPLS------- 134

  Fly   218 PTKQPNKNQTKEKS--NI--QTNEETQQNNLPSPSRNKYQNARRVLNSAETQNLPGRESQLQELR 278
            |..:|:..:..|.|  ||  :|..::....|....::.:|:.::.|::|..:.|..||::...:.
Zfish   135 PISRPSPTRLNETSCTNIIPRTEGKSPVMRLFPMKKSGFQSVKQALHTAVPERLLSREAERAAIV 199

  Fly   279 EFFSNHLESQTSGSLYVSGQPGTGKTACLSLLLRDPD-FSKRLQRVYINCTSIASVGAVYKKLCT 342
            .|..||:.::...|||:||.|||||||||:.:|::.. ..|.:|.|.|||.::.|..|::..|..
Zfish   200 SFLQNHVVAEKPSSLYISGAPGTGKTACLNCVLQEQKALLKGIQTVVINCMNLRSSHAIFPLLGE 264

  Fly   343 ELQLKVSGRTERDHLEAIQRHLKTAKRMLLLVLDEIDQLCTSRQEVLYTIFEWPALPGSRILLVG 407
            :|::.......|     ::::|.::...:||||||:|||.:..|||||||||||.||.||:.|:|
Zfish   265 QLEVPKGNSQAR-----LEKYLTSSGPTVLLVLDEMDQLDSKSQEVLYTIFEWPYLPKSRVCLIG 324

  Fly   408 IANSLDLTDRALMRLNARCELKPRLMHFPPYSKQQIVEIFKSRLAEAEVLDVFPPVTLQLLAAKV 472
            |||:||||||.|.||.|:...:|:|::|||||.:::..|.:.||.:.....|.....:|..|.||
Zfish   325 IANALDLTDRILPRLQAKPHCRPKLLNFPPYSHEELNAIVQDRLTQVSGEGVLDAAAVQFCARKV 389

  Fly   473 SAISGDVRRALDIGRRVVEIAEQQKRDGEKEFNMKALQLEGKDAVEAKEKQDTLKPVQVTQVAAV 537
            ||:|||.|:||||.||.|||.|...|.          ::..:....:|     :..|.|.|||.|
Zfish   390 SAVSGDARKALDICRRAVEIVEAGDRS----------KMASEPTASSK-----VSRVSVPQVARV 439

  Fly   538 LNKVYGASQNLEEDIEASFPLQQKLMLCTLVLMLRNERNKDISMGRLHEVYRRVCAKRNILALDQ 602
            |::|||...........||||||||::|.|:|::||.::|:|.:|:|.|||.::|.:|.:..:.|
Zfish   440 LSEVYGDRMASSSGDGESFPLQQKLLVCCLLLIIRNGKSKEIQLGKLCEVYSKLCKQRQVGGVGQ 504

  Fly   603 AEFTGTVDLVETRGILRIMRKKEPRLHKVLLQWDEEEVHAALSDKQLIASILS 655
            .|......|:|:||||.:.:.|:.||.|:.|:.:|.:|..||.|:.|:.|||:
Zfish   505 TECLSLCSLLESRGILTLKKAKDARLTKISLKIEERDVEHALKDRTLLGSILA 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc6	NP_648247.1	CDC6	256..646	CDD:441083	156/390 (40%)
cdc6	NP_001120805.1	PHA03132	11..>229	CDD:222997	75/287 (26%)
		CDC6	184..548	CDD:441083	154/383 (40%)